Human Apoptosis Protease Activating Factor-1, APAF-1 ELISA Kit from Bioassay Technology Laboratory

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis