Fig 1: Markers of tubular damage (urinary CysC and KIM-1) in patients with ADHF at day 3 of hospitalisation. Box plot diagrams [median (IQR)] refer to (A) cystatin C (CysC) and (B) Kidney Injury Molecule 1 (KIM-1) in the subgroups of patients with ADHF as described in Figure 4A. (C,D) Spearman correlation (Rho) between urinary VDBP levels and CysC and KIM-1, respectively, in all patients with ADHF. (E) ROC curve analyses (C-Statistics) for the prediction of renal function deterioration presentation in patients with ADHF (N = 34). AUC indicates area under the curve.