X-CLARITY™ Hydrogel Solution Kit from Logos Biosystems

Product Specs
ItemX-CLARITY™ Hydrogel Solution Kit
CompanyLogos Biosystems
Price Supplier Page View Company Product Page
Catalog NumberC1310X
Quantity1 kit
ApplicationsTissue Clearing
TypeReagents
Components1 x 1 L X-CLARITY™ Hydrogel Solution 1 x 2.5 g X-CLARITY™ Polymerization Initiator

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Logos Biosystems

8F, 18 Gosan-ro 148beon-gil

Gunpo-si, Gyeonggi-do 15850

Korea, Republic of (South Korea)

Phone: +82-31-478-4185
Fax: +82-31-360-4277

Email: sales@logosbio.com

Company Profile

Website: www.logosbio.com

(1) Comparative Analysis of Clearing Methods for 3D Imaging of the Vasculature in Mineralized Mouse TissuesiScienceApril 17, 2026Azeez O. Ishola, Athira Pillai, Taeyong Ahn, RE-JOIN Consortium, Chih-Wei Hsu, Brendan Lee, Nele Haelterman, Joshua D. WytheX-CLARITY Hydrogel Solution with 0.25% (w/v) of polymerization initiator VA-044 (Logos Biosystems, C1310X) and incubated at 4°C for 24 hr. Cross-linking of the hydrogel was then thermally induced at 37°C under

(2) Optimization of Tissue Clearing Methods and Imaging Conditions for 3D Visualization of the Vasculature of the Adult Murine KneebioRxivJune 28, 2025Azeez O. Ishola, Athira Pillai, Taeyong Ahn, RE-JOIN Consortium, Chih-Wei Hsu, Brendan Lee, Nele A Haelterman, Joshua D. WytheX-CLARITY Hydrogel Solution with 0.25% (w/v) of polymerization initiator VA-044 (Logos Biosystems, C1310X) and incubated at 4°C for 24 hr. Cross-linking of the hydrogel was then induced thermally by incubating

(3) Fast formation and maturation enhancement of human liver organoids using a liver-organoid-on-a-chipFrontiers in Cell and Developmental BiologyAugust 14, 2024Jae Hee Byeon, Da Jung Jung, Hyo-Jeong Han, Woo-Chan Son, Gi Seok Jeongthe hLOs, a clearing step was carried out. In brief, the fixed organoids were embedded in hydrogel (C1310X X-Clarity Hydrogel Solution Kit, Logos Biosystems, Inc., Anyang, Korea) and incubated at 4°C for 1 day.

(4) Pre-hypertrophic chondrogenic enhancer landscape of limb and axial skeleton developmentNature CommunicationsJune 6, 2024Fabrice Darbellay, Anna Ramisch, Lucille Lopez-Delisle, Michael Kosicki, Antonella Rauseo, Zahra Jouini, Axel Visel, Guillaume Andreyclearing method. Briefly, tissue was incubated in a Bis-free Hydrogel X-CLARITY™ Hydrogel Solution Kit (C1310X, Logos Biosystems) for 3 days at 4 °C, allowing diffusion of the hydrogel solution into the tissue.

(5) Chronic ultraviolet irradiation induces memory deficits via dysregulation of the dopamine pathwayExperimental & Molecular MedicineJune 3, 2024Kyeong-No Yoon, Sun Yong Kim, Jungeun Ji, Yidan Cui, Qing‐Ling Quan, Gunhyuk Park, Jang-Hee Oh, Ji Su Lee, Joon-Yong An, Jin Ho Chung, et al.with 4′,6-diamidino-2-phenylindole (2 μg/ml) for 5 min and mounted in X-CLARITY Mounting Solution (#C1310X; Logos Biosystems, Annandale, VA). Immunofluorescence images of the sections were captured using a confocal

(6) Revealing the MRI‐Contrast in Optically Cleared BrainsAdvanced ScienceJune 1, 2024Shimrit Oz, Galit Saar, Shunit Olszakier, Ronit Heinrich, Mykhail O. Kompanets, Shai BerlinLogos Biosystems). Briefly, whole brains were infused with hydrogel monomers at 4 °C overnight (cat #: C1310X, Logos Biosystems) and a subsequent hydrogel polymerization step was performed at 37 °C for 3 h at −90

(7) Datasets assessing lipid-content in optically cleared brainsData in BriefNovember 30, 2023Shimrit Oz, Galit Saar, Shunit Olszakier, Ronit Heinrich, Mykhail O. Kompanets, Shai Berlinbrains (Figs 2 and 3) and slices (Fig. 4) were infused with hydrogel monomers at 4 °C overnight (cat #: C1310X, Logos Biosystems) and a subsequent hydrogel polymerization step was performed at 37 °C for three hours

(8) EZ Clear for simple, rapid, and robust mouse whole organ clearingeLifeOctober 11, 2022Chih-Wei Hsu, Juan Cerda, Jason M Kirk, Williamson D Turner, Tara L Rasmussen, Carlos P Flores Suarez, Mary E Dickinson, Joshua D WytheX-CLARITY Hydrogel Solution with 0.25% (w/v) of polymerization initiator VA-044 (Logos Biosystems, C1310X) at 4°C for 24 hr. The hydrogel infused brain was then thermo-induced crosslinked for 3 hr at 37°C under

(9) Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonadScience advancesMay 27, 2022Mayère C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, et al.embryonic stages E11.5, E12.5, E13.5, and E16.5 were incubated in 5 ml of X-CLARITY Hydrogel Solution Kit (C1310X, Logos Biosystems) for 3 days at 4°C, allowing diffusion of the hydrogel solution into the tissue. Polymerization

(10) Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancerNature CommunicationsDecember 13, 2021Raquel Rouco, Olimpia Bompadre, Antonella Rauseo, Olivier Fazio, Rodrigue Peraldi, Fabrizio Thorel, Guillaume Andreyclearing method. Briefly, tissue was incubated in a Bis-free Hydrogel X-CLARITY™ Hydrogel Solution Kit (C1310X, Logos Biosystems) for 3 days at 4 °C, allowing diffusion of the hydrogel solution into the tissue.

(11) Presynaptic Boutons That Contain Mitochondria Are More StableFrontiers in Synaptic NeuroscienceJanuary 10, 2020Robert M. Lees, James D. Johnson, Michael C. Ashbycentered 2 mm from each end", Bone cement,DePuy,With gentamicin, Hydrogel solution kit,Logos biosystems,,C1310X Electrophoretic tissue clearing solution,Logos biosystems,,C13001 Mounting solution (cleared brain),Logos biosystems

(12) The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disordersJournal of NeuroinflammationDecember 1, 2019Patrick Miller-Rhodes, Cuicui Kong, Gurpreet S. Baht, Priyanka Saminathan, Ramona M. Rodriguiz, William C. Wetsel, Harris A. Gelbard, Niccolò TerrandoBiosystems). Sections were first saturated in 1 mL hydrogel solution (X-CLARITY™ Hydrogel Solution Kit, #C1310X, Logos Biosystems) at 4 °C for 24 h and were subsequently incubated in the polymerization system for

(13) High Resolution Imaging of Mouse Embryos and Neonates with X‐Ray Micro‐Computed TomographyCurrent Protocols in Mouse BiologyJune 14, 2019Chih‐Wei Hsu, Sowmya Kalaga, Uchechukwu Akoma, Tara L. Rasmussen, Audrey E. Christiansen, Mary E. Dickinson25% (w/v) stock solution, add 2.5 g of the X-CLARITY™ Polymerization Initiator (Logos Biosystem, Cat# C1310X) in 10 ml of 1X PBS (pH 7.2), mix well until fully dissolved. 2. Aliquot 500 ul per 1.5 ml microtube.

(14) A transgenic inducible GFP extracellular-vesicle reporter (TIGER) mouse illuminates neonatal cortical astrocytes as a source of immunomodulatory extracellular vesiclesScientific reportsFebruary 28, 2019Neckles VN, Morton MC, Holmberg JC, Sokolov AM, Nottoli T, Liu D, Feliciano DM.in a hydrogel monomer solution made up with the X-Clarity Hydrogel Solution kit (Logosbio: Catalog #C1310X). The following day, tissue embedded in the hydrogel monomer was placed within the X-Clarity Logos Polymerization

(15) Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse ModelFrontiers in immunologyJanuary 1, 2019Velagapudi R, Subramaniyan S, Xiong C, Porkka F, Rodriguiz RM, Wetsel WC, Terrando N.Active Tissue Clearing Each 1 mm thick slice was incubated in 1 mL X-CLARITYTM Hydrogel Solution (#C1310X; Logos Biosystems, Annandale, VA) at 4◦ C for 24 h. After incubation, polymerization was performed using

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