Fig 1: Distribution of GH in cross-sectional cohort. (A) ACLF group showed higher GH levels than HC, CHB, and LC group, but no difference from LC-AD group, and the r-value of the correlation between GH levels and severity was 0.462, p < 0.001. (B) HC group showed higher IGF-1 levels than LC, LC-AD, and ACLF group, but no difference from CHB group, and the r value of the correlation between IGF-1 levels and severity was -0.641, p < 0.001. ACLF, acute-on-chronic liver failure; CHB, chronic hepatitis B; GH, growth hormone; HC, health control; IGF-1, insulin-like growth factor-1; LC, liver cirrhosis; LC-AD, liver cirrhosis-acute decompensation. *** < 0.001.