ERBB3 ELISA Kit (Human) (OKCD01202) from Aviva Systems Biology

Description

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134)

Product Specs
ItemERBB3 ELISA Kit (Human) (OKCD01202)
CompanyAviva Systems Biology
Price $650.00Supplier Page View Company Product Page
Catalog NumberOKCD01202
Quantity96WELLS
ApplicationsELISA-Sandwich
DetectionColorimetric
ReactivityHomo sapiens, Human
Sample TypeSerum, plasma, tissue homogenates and other biological fluids
Sensitivity< 32 pg/mL
Detection TargetReceptor tyrosine-protein kinase erbB-3
Assay Time3h
NCBI Gene AliasesMDA-BF-1, LCCS2, p180-ErbB3, VSCN1, c-erbB3, p85-sErbB3, FERLK, erbB3-S, HER3, c-erbB-3, ErbB-3, p45-sErbB3
Detection Range0.156-10ng/mL
Gene Nameerb-b2 receptor tyrosine kinase 3
ComponentsStop Solution
Avidin/HRP Conjugate
Standard Diluent
Conjugate Diluent
100X Biotinylated ERBB3 Detector Antibody
Detector Antibody Diluent
30X Wash Buffer
Anti-ERBB3 Microplate
TMB Substrate
ERBB3 Lyophilized Standard
YieldRecovery Range: serum(n=5): 84-104: 101
EDTA plasma(n=5): 79-104: 88
heparin plasma(n=5): 96-104: 99

Specifications/Features

This assay has high sensitivity and excellent specificity for detection of V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3). No significant cross-reactivity or interference between V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) and analogues was observed

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