MGMT ELISA Kit (Rat) (OKCD02640) from Aviva Systems Biology

Description

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated

Product Specs
ItemMGMT ELISA Kit (Rat) (OKCD02640)
CompanyAviva Systems Biology
Price $700.00Supplier Page View Company Product Page
Catalog NumberOKCD02640
Quantity96WELLS
ApplicationsELISA-Sandwich
DetectionColorimetric
ReactivityRat, Rattus norvegicus
Sample TypeTissue homogenates and other biological fluids
Sensitivity27 pg/mL
Detection TargetMethylated-DNA--protein-cysteine methyltransferase
Assay Time3h
ComponentsMGMT Lyophilized Standard
Stop Solution
Standard Diluent
Conjugate Diluent
Anti-MGMT Microplate
Detector Antibody Diluent
30X Wash Buffer
100X Avidin-HRP Conjugate
100X Biotinylated MGMT Detector Antibody
TMB Substrate
Gene NameO-6-methylguanine-DNA methyltransferase
Detection Range78.12-5000pg/mL

Specifications/Features

This assay has high sensitivity and excellent specificity for detection of O-6-Methylguanine DNA Methyltransferase (MGMT). No significant cross-reactivity or interference between O-6-Methylguanine DNA Methyltransferase (MGMT) and analogues was observed

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