Description
This cell line is a HEK-293-CNG cell line that expresses a recombinant human LHCGR. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.
cAMP dependent human LHCGR cell-based assay;cell-based high-throughput screening of human LHCGR agonists/antagonists