pGL4.37[luc2P/ARE/Hygro] Vector from Promega

Product Specs
ItempGL4.37[luc2P/ARE/Hygro] Vector
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberE3641
Quantity20microg
Molecular Weight~89kDa
Nucleic Acid TypeReporter Vectors
Expression System (standardized)Mammalian
Vector NamepGL4.37[luc2P/ARE/Hygro]

Add to Compare List

Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) A covalent allosteric molecular glue suppresses NRF2-dependent cancer growthCancer DiscoveryMay 1, 2026Nilotpal Roy, Tine Wyseure, I-Chung Lo, Justine Lu, Christie L. Eissler, Steffen M. Bernard, Ilah Bok, Aaron N. Snead, Albert Parker, U-Ging Lo, et al.containing 100 ng/well of the ARE luciferase reporter plasmid [pGL4.37(luc2P/ARE/Hygro), Promega cat. #E3641], 100 ng/well of a control Renilla luciferase plasmid [pGL4.75(hRluc/CMV), Promega cat. #E6931], and

(2) Drynachromoside A from Drynaria fortunei attenuates oxidative stress and fibrosis of diabetic nephropathy via activating Nrf2 in vitro and in vivoRedox ReportDecember 31, 2025Huankai Yao, Jindong Li, Ruiqing Wu, Dan Du, Fengwei Ai, Yan Liby Abcam (Cambridge, UK). The ARE luciferase reporter plasmid (pGL4.37[luc2P/ARE/Hygro]) (Cat. no. E3641), Renilla luciferase reporter plasmid (pRL-TK) (Cat. no. E2241) and dual-luciferase reporter assay system

(3) Neuroprotective effects of α-lipoic acid on ischemia/reperfusion injury in global cerebral ischemia mouse modelScientific ReportsDecember 30, 2025Soyoung Kwak, Ji Sun Lim, Shin Kim, Ye Jin Kwon, Mi-Hee Yu, Mee-Na Park, Dong Kyu Choi, Jeong-Ho Hong, Hae Won Kimelement (ARE) luciferase assay HT22 cells were transfected with the pGL4.37[luc2P/ARE/Hyg] vector (E3641, Promega, Madison, WI, USA) using Lipofectamine 2000 (Invitrogen, Carlsbad, CA, USA). Stable HT22-ARE

(4) Phosphorylation of eIF2α suppresses the impairment of GSH/NADPH homeostasis and mitigates the activation of cell death pathways, including ferroptosis, during ER stressMolecules and CellsMarch 13, 2025Hien Thi Thi Le, Yong Hwan Kim, Mi-Jeong Kim, Seung Hwa Hyun, Hyeeun Kim, Su Wol Chung, Yeonsoo Joe, Hun Taeg Chung, Dong-Myung Shin, Sung Hoon BackpCGN-ATF4-IRES-EGFP) were described previously (Dang et al., 2023). pGL4.37-ARE-firefly luciferase (Promega, E3641) contains 4 copies of an antioxidant response element (ARE) that drives transcription of the luciferase

(5) Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathwaysCell reportsJuly 25, 2023Ganapathy AS, Saha K, Wang A, Arumugam P, Dharmaprakash V, Yochum G, Koltun W, Nighot M, Perdew G, Thompson TA, et al.E6921 luc2P/XRE pGL4.43,"Promega, Madison, WI",Cat #E4121 luc2P/ARE pGL4.37,"Promega, Madison, WI",Cat# E3641 pGL4.26,"Promega, Madison, WI",Cat #E8441 pCRISPR- LVSG03,"Genecopoeia, Rockville, MD",Cat# CCPCTR01 Software

(6) Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2Clinical Cancer ResearchApril 3, 2023Yang Liu, Fu-Ju Chou, Fengchao Lang, Meili Zhang, Hua Song, Wei Zhang, Dionne L. Davis, Nicole J. Briceno, Yang Zhang, Patrick J. Cimino, et al.according to the manufacturer’s protocol. Forty-five nanogram of plasmid pGL4.37[luc2P/ARE/Hygro] (Promega, E3641) was mixed with 5 ng pRL-CMV (Promega, E2261) and EGFP-Nrf2 plasmids (Addgene 21549). The plasmid mixtures

(7) Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigaretteToxicology ReportsFebruary 15, 2023Tsuneo Hashizume, Shinkichi Ishikawa, Kazushi Matsumura, Shigeaki Ito, Toshiro FukushimaBEAS-2B cells were transfected with anti-oxidant responsive element (ARE) luciferase reporter vector (E3641; Promega, Madison, WI, USA) as previously reported [32]. Cells (5 ×103 cells/well) were seeded into

(8) Z-REX uncovers a bifurcation in function of Keap1 paralogseLifeOctober 27, 2022Van Hall-Beauvais A, Poganik JR, Huang KT, Parvez S, Zhao Y, Lin HY, Liu X, Long MJC, Aye Y.(Cornell University),PMCID:PMC2292119,N/A Recombinant DNA reagent,pGL4.37[luc2P/ARE/Hygro],Promega,Cat# E3641,N/A Recombinant DNA reagent,pGL4.75[hRluc/CMV],Promega,Cat# E6931,N/A Recombinant DNA reagent,pCDNA3

(9) In vitro–In vivo Hybrid Approach for Studying Modulation of NRF2 in Immortalized Bovine Mammary CellsFrontiers in Animal ScienceJune 21, 2021Hunter R. Ford, Sebastiano Busato, Massimo Bionazabove. Dual Luciferase Reporter Assay MACT cells were cotransfected with the pgl4.37 [luc2P/ARE/Hygro] [Cat #E3641, Promega Corporation, Madison, WI] and pRL-TK [Cat #E2241, Promega Corporation] plasmids at a 40:1 ratio

(10) Evaluation of the Biological Effects of Novel Tobacco Product Vapor Using Two- or Three-Dimensional Culture Systems of Human Bronchial EpitheliaApplied In Vitro ToxicologyMarch 1, 2021Sakura Mori, Kanae Ishimori, Ikuya Tanabe, Shinkichi IshikawaCollection (Manassas, VA). BEAS-2B cells containing an antioxidant response element (ARE) reporter gene (no. E3641; Promega, After 24 hours of exposure to test product AqE, the ARE reporter gene activity of the cells

(11) A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axisRedox biologyMay 1, 2020Chen Y, Evankovich JW, Lear TB, Tuncer F, Kennerdell JR, Camarco DP, Shishido MS, Liu Y, Chen BB.Dual-Glo Luciferase Assay System (E2920), Nano-Glo Luciferase Assay System (N1120), pGL4.37[luc2P/ARE/Hygro] Vector (E3641) and pNLF1-NRF2 [CMV/neo] Vector (N1391) were from Promega. Anti-DCAF1 antibody (mouse specific) (sc-376850),

(12) Assessment of pesticides in surface water samples from Swedish agricultural areas by integrated bioanalysis and chemical analysisEnvironmental Sciences EuropeDecember 1, 2019Johan Lundqvist, Claudia von Brömssen, Anna Kjerstine Rosenmai, Åsa Ohlsson, Theo Le Godec, Ove Jonsson, Jenny Kreuger, Agneta Oskarssonluciferase is under the control of an antioxidant responsive element (pGL4.37[luc2P/ARE/Hygro] Vector, E3641) purchased from Promega. The transfection efficiency was controlled for by co-transfection of a renilla

(13) The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic StressCell metabolismSeptember 4, 2018Kim KH, Son JM, Benayoun BA, Lee C.V79520 Renilla luciferase,Promega Corporation,Cat#E2231 pGL4.37[luc2P/ARE/Hygm]),Promega Corporation,Cat#E3641 Software and Algorithms,, kallisto 0.43.0,"Bray et al., 2016",https://pachterlab.github.io/kallisto/download DESeq2

(14) T-REX on-demand redox targeting in live cellsNature ProtocolsDecember 1, 2016Saba Parvez, Marcus J C Long, Hong-Yu Lin, Yi Zhao, Joseph A Haegele, Vanha N Pham, Dustin K Lee, Yimon Ayecell culture HaloTag TMR ligand (Promega, cat. no. G8251) Luciferase plasmid (Promega, cat. no. E3641) pCMV-Renilla luciferase plasmid (Promega, cat. no. E6931) ARE-GFP plasmid (Promega, CCS-0020G)

(15) Fungicide prochloraz induces oxidative stress and DNA damage in vitroFood and Chemical ToxicologyMarch 1, 2016J. Lundqvist, B. Hellman, A. Oskarsson

Be the First to Write a Review!