Fig 1: Correlation of APOs expression with immune infiltration in EC by ssGESA. APOD or APOE expression were positively correlated those tumors infiltrating immune cells of CD4+ naïve T cells (CD4 Naïve T) (A, E), CD8+T cells (B, F), CD8+ naïve T cells (CD8 Naïve T) (C, G), cytotoxic T cell (CD3+CD8+CD28+T cell, Tc) (D, H).
Fig 2: APOE and APOD regulated by estrogen modulated the migration of endometrial cancer cell. (A) Western blotting analysis of APOD and APOE in ISHKAWA cells treated with control (DMSO, solvent of E2) or 10-8mol/L E2 for 48 hours; (B) Wound healing assay was performed to assess cell migration. Cells were transfected with control (DMSO), si-APOD RNA and si-APOE RNA. Migratory cells were observed using an IX711 phase contrast microscope (Olympus Corporation) at 0 and 48 h (magnification, ×200). E2: 17β-estradiol; si-APOD RNA: lentivirus of siRNA targeting APOD; si-APOE RNA: lentivirus of siRNA targeting APOE. ns: no significance; **p < 0.05.
Fig 3: Kaplan–Meier analysis of association between EC prognosis and the expression of APOC1 (A), APOC2 (B), APOD (C), APOE (D), APOL3 (E), APOL4 (F), APOLD1 (G) and APOO (H).
Supplier Page from OriGene Technologies for Apolipoprotein D (APOD) Human shRNA Plasmid Kit (Locus ID 347)