Oligomycin A from Cayman Chemical

Product Specs
ItemOligomycin A
CompanyCayman Chemical
Price $154.00Supplier Page View Company Product Page
Catalog Number11342
Quantity5 mg
Research AreaApoptosis, Cancer, Cell Biology, Cell Death, Mitochondrial Biology
FormatA crystalline solid
Molecular Weight791.1
Purity≥95%
Storage-20
FormulaC45H74O11
OriginUSA
Source/Expression SystemBacterium/Streptomyces sp

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Redox index and capacity analysis (RICA) reveals NAD biology changes in T cell responses in vitro and ex vivoJ ImmunolApril 15, 2026Alicia M. Bostwick-Galaviz, Edward J. Usherwoodplated in a 96-well U-bottom plate. Cells were resuspended in TCM +/− 1 μM oligomycin (Cayman Chemical 11342) and incubated at 37 °C for 1 hour. Cells were washed with 200 μL cold RICA buffer, then Fc blocked

(2) Suppression of mitochondrial energy production by a photosynthetic bacterial cupredoxin peptide inhibits tumor growthSignal Transduct Target TherApril 7, 2026Samer A. Naffouje, Duy Binh Tran, David J. Rademacher, Valentina Botti, Konstantin Christov, Albert Green, Weiguo Li, Ngoc Hai Trieu Phong, Salvatore Cannistraro, Anna Rita Bizzarri, et al.confocal chamber and incubated for 24 h. These cell lines were then treated with oligomycin A (5 µM,94 11342, Cayman, MI) and aurB (50 µM) for 24 h. One group of cells was cultured in media alone as a control group

(3) Redox imbalance dictates dependence on GOT1 versus GOT2 for rod photoreceptor health during aging and stressbioRxivApril 7, 2026Meini Chen, Eric Weh, Moloy T. Goswami, Katherine M. Weh, Heather Hager, Peter Sajjakulnukit, Avi Weingarten, Shubha Subramanya, Nicholas Miller, Sraboni Chaudhury, et al.and the temperature was maintained at 37°C. Oligomycin-A (Cayman Chemical, Ann Arbor, MI, USA, Cat #11342), FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone, Cayman Chemical, Cat #15218) and KCN (Potassium

(4) Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activityCell ReportsMarch 24, 2026Prabhakar Arumugam, Cortney E. Heim, Rachel W. Fallet, Dhananjay D. Shinde, Vinai C. Thomas, Rafael J. Argüello, Tammy Kielianbeads,Miltenyi Biotech,130-120-337 2-deoxy-glucose,Cayman Chemical,14325 Oligomycin,Cayman Chemical,11342 FCCP,Cayman Chemical,15218 Rotenone,Cayman Chemical,13995 Antimycin A,Cayman Chemical,34799 RPMI-1640,Cytiva

(5) Zonal hepatocellular responses to acute ethanol consumption: impacts on mitochondrial function and liver metabolismToxicological SciencesMarch 2, 2026Matthew T. Savoca, Kenji Takemoto, Jiangting Hu, Li Li, Zhi Zhong, John J. LemastersXFe96 Analyzer (Agilent). Mitochondrial stress tests comprised sequential addition of oligomycin (1μM, 11342, Cayman Chemical, Ann Arbor, MI, USA), carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP, 1μM,

(6) Hypoxia restores the acidosis-induced inhibition of cancer cell disseminationCell ReportsFebruary 24, 2026Se Jong Lee, Alice Amitrano, Qinling Yuan, Debanik Choudhury, Konstantin Stoletov, Bhawana Agarwal, Avery Tran, Inês Godet, James McCann, Ryan Huizar, et al.Agilent) (pH 7.4). The final concentrations of 2.5 mM glucose (103577-100, Agilent), 1.5 μM oligomycin (11342, Cayman Chemical) and 25 mM 2-DG (14325, Cayman Chemical) were used as injected compounds. ATP rate

(7) Lipopolysaccharide induces HIF-1α accumulation via MAPK p38–mediated mRNA stabilization and dexamethasone-sensitive protein stabilizationJournal of Biological ChemistryFebruary 1, 2026Chloe Lockwood, Kalbinder K. Daley, John D. O’Neil, Katherine J. Heighes, Sally A. Clayton, Andrew R. ClarkmM, Sigma–Aldrich; catalog no.: G7021), (B) oligomycin A (1 μM, Cayman Chemical Company; catalog no.: 11342), (C) carbonyl cyanide p-trifluoromethoxyphenylhydrazone (5 μM, Cayman Chemical Company; catalog no.:

(8) IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanomaCancer CellJanuary 22, 2026Triantafyllia Karakousi, Vanessa Cristaldi, Maria Luiza Lopes de Oliveira, Ines Delclaux, Naomi R. Besson, Luiz Henrique Geraldo, Tania J. González-Robles, Devyon R. McDonnough, Daniel Martinez-Krams, Gabrielle da Silva, et al.manufacturer recommendations with final well concentrations of Oligomycin (Cayman Chemical Company, 11342) 2.5umol/L, FCCP (Cayman Chemical Company,15218) 2umol/L, and Antimycin/Rotenone (Sigma Aldrich, A8674/Cayman Chemical Company

(9) Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterationsSignal Transduction and Targeted TherapyJanuary 16, 2026Philipp Hafner, Steffen J. Keller, Xun Chen, Asma Alrawashdeh, Huda Jumaa, Friederike I. Nollmann, Solène Besson, Judith Kemming, Oliver Gorka, Tonmoy Das, et al.MRTX1133 (HY-134813) were purchased from MedChemExpress. The metabolism-related drugs oligomycin A (11342), rotenone (13995), antimycin A (19433), 2-deoxyglucose (14325), and 6-aminonicotinamide (10009315)

(10) Metabolic adaptations rewire CD4+ T cells in a subset-specific manner in human critical illness with and without sepsisNat ImmunolJanuary 15, 2026Matthew T. Stier, Allison E. Sewell, Erin L. Mwizerwa, Chooi Ying Sim, Samantha M. Tanner, Casey M. Nichols, Heather H. Durai, Erin Q. Jennings, Paul Lindau, Erin M. Wilfong, et al.cat. no. 14325, 100 mM), mitochondrial ATP synthase inhibitor oligomycin A (Cayman Chemical, cat. no. 11342, 1.5 μM), glutaminase 1 (GLS1) glutaminolysis inhibitor CB-839 (MedChemExpress, cat. no. HY-12248, 10

(11) Intracellular lactate dynamics in Drosophila neuronsiScienceOctober 17, 2025Matthew S. Price, Elham Rastegari, Richa Gupta, Katie Vo, Travis I. Moore, Kartik VenkatachalamP4762 L-cysteine,Calbiochem,Cat# 2430 Trehalose,Sigma-Aldrich,Cat# 625625-50GM Oligomycin A,Cayman Chemical,Cat# 11342 Sodium oxamate,Selleck Chemicals,Cat# S6871 Mannitol,Calbiochem,Cat# 443907 Dextrose (glucose),Fisher

(12) Cells adapt to extracellular acidic pH through TM9SF3-mediated PI(4,5)P2 flopNat CommunOctober 6, 2025Keisuke Sako, Yusuke V. Morimoto, Shin Morioka, Junya Hasegawa, Hiroyuki Nakajima, Moe Fukumoto, Yuya Nishida, Yasunori Shintani, Junko Sasaki, Takehiko Sasaki, et al.were used in this study: Valinomycin and nigericin (P35379, Thermo Fisher Scientific); Oligomycin A (11342, Cayman Chemicals); BAPTA (B-6769, Molecular Probes); Ionomycin (407950, Calbiochem); FCCP (C2920, Sigma-Aldrich);

(13) Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal micePharmacological ResearchSeptember 1, 2025Myriam Boeck, Hitomi Yagi, Pia Lundgren, Aldina Pivodic, Anders K. Nilsson, Yan Zeng, Chuck T. Chen, Taku Kasai, Deokho Lee, Shen Nian, et al.were collected. For inhibition of mitochondrial ATP synthase, oligomycin A (0.25 μg/g body weight) (#11342, Cayman Chemical, Ann Arbor, MI, USA; 0.25 μg/μL in PBS with 30 % dimethylsulfoxide) [39] was intraperitoneally

(14) TMEM65 functions as the mitochondrial Na+/Ca2+ exchangerNature Cell BiologyAugust 1, 2025Jim Lu Zhang, Yu-Chen Chang, Po-Hsuan Lai, Han-I Yeh, Chen-Wei Tsai, Yu-Lun Huang, Tsung-Yun Liu, I-Chi Lee, North Foulon, Yan Xu, et al.resuspended in 2 mL of TRB supplemented with 4-μM rotenone (Cayman, 13995) and 1.5-μM oligomycin (Cayman, 11342) and incubated on ice for 5 minutes. The sample was then loaded into a stirred quartz cuvette for fluorescence

(15) ATP synthase inhibition, an overlooked confounding factor in the mitochondrial stress testPLoS OneJuly 17, 2025Jesse Corbin, Eric A. Lehoux, Isabelle Catelasconsumption, after sequential injections of oligomycin A (Cayman Chemical, Ann Arbor, MI, catalog no. 11342), trifluoromethoxy carbonylcyanide phenylhydrazone (FCCP; Cayman Chemical), and rotenone together with

(16) Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survivalElifeMay 21, 2025Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, et al.At various times throughout the experiment Oligomycin-A (Cayman Chemical, Ann Arbor, MI, USA, Cat # 11342), FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone, Cayman Chemical, Cat# 15218), and KCN (Potassium

(17) Metabolic reprogramming driven by Ant2 deficiency augments T Cell function and anti-tumor immunity in miceNat CommunMay 8, 2025Omri Yosef, Leonor Cohen-Daniel, Oded Shamriz, Zahala Bar-On, Wajeeh Salaymeh, Amijai Saragovi, Ifat Abramovich, Bella Agranovich, Veronika Lutz, Joseph Tam, et al.following compound concentrations were used for the OCR measurements: 2 µM Oligomycin (Cayman Chemicals, 11342), 2 µM FCCP (Cayman Chemicals, 15218), and 1 µM Antimycin-A (Cayman Chemicals, 19433) and Rotenone (Cayman Chemicals

(18) Rescue of the First Mitochondrial Membrane Carrier, the mPiC, by TAT-Mediated Protein Replacement TreatmentInt J Mol SciMay 5, 2025Samar Zabit, Orly Melloul, Michal Lichtenstein, Erin L. Seifert, Haya Lorberboum-Galskiperformed at 37 °C according to the manufacturer’s instructions. Briefly, 18 µM oligomycin (Cat No. 11342; Cayman Chemical, Ann Arbor, MI, USA), 20 µM trifluoromethoxy carbonyl cyanide phenylhydrazone (FCCP)

(19) Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolismThe Journal of ImmunologyMay 1, 2025KayLee K Steiner, Arissa C Young, Andrew R Patterson, Ayaka Sugiura, McLane J Watson, Samuel E J Preston, Anton Zhelonkin, Erin Q Jennings, Channing Chi, Darren R Heintzman, et al.bioanalyzer using the Mitostress assay (Agilent; 103015-100) with 1 μM oligomycin (Cayman Chemical; 11342), 2 μM FCCP (Cayman Chemical; 15218), and 0.5 μM rotenone (Cayman Chemical; 13995)/antimycin A (Cayman Chemical

(20) Serine supplementation suppresses hypoxia-induced pathological retinal angiogenesisTheranosticsApril 9, 2025Hitomi Yagi, Chenxi Qiu, Yan Zeng, Myriam Boeck, Shen Nian, Chuck T. Chen, Jarrod C Harman, Taku Kasai, Jeff Lee, Victoria Hirst, et al.used for mitochondrial ATP synthase inhibitor oligomycin (0.25 µg/g body weight, i.p., P12 to P16 23, #11342, Cayman. A higher dose at 0.5 µg/g body weight caused increased mortality) or the inhibitor of high

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Oligomycin A from Cayman Chemical

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Oligomycin A from Cayman Chemical

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