Oligomycin Complex from Cayman Chemical

Product Specs
ItemOligomycin Complex
CompanyCayman Chemical
Price $97.00Supplier Page View Company Product Page
Catalog Number11341
Quantity5 mg
Research AreaApoptosis, Cell Biology, Cell Death, Mitochondrial Biology
FormatA crystalline solid
Purity≥95% (Mixture of A, B, C)
Storage-20
OriginISR
TypeInhibitors

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Mitochondrial acid-sensing ion channel 1a deficiency induces mitochondrial dysfunction in pulmonary arterial smooth muscle cellsAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyApril 1, 2026Megan N. Tuineau, Lindsay M. Herbert, Heaven E. Medina, Jay S. Naik, Thomas C. Resta, Nikki L. JerniganAgent,Target,Company,Cat #,Concentration,Vehicle oligomycin,mitochondrial complex V,Cayman Chemical,11341,1 μM,DMSO FCCP,oxidative phosphorylation,Cayman Chemical,15218,"1, 20 μM",DMSO rotenone,mitochondrial

(2) S1P-S1PR1 signaling impairs CD8+ T cell metabolism and effector function in tumorsEMBO ReportsMarch 19, 2026Debashree Basak, Puspendu Ghosh, Anupam Gautam, Ishita Sarkar, Arpita Bhoumik, Soham Chowdhury, Shaun Mahanti, Anwesha Mandal, Rajeswari Chakraborty, Anwesha Kar, et al.pyruvate,Gibco,11360-070 D-glucose,Cayman Chemicals,11360-070 Cell-Tak,Corning,354240 Oligomycin,Cayman Chemicals,11341 FCCP,Cayman Chemicals,15218 Rotenone,Cayman Chemicals,13995 Antimycin A,Cayman Chemicals,19433 2-deoxy-D-glucose,Cayman Chemicals

(3) Branched-chain α-keto acids impair glucose-stimulated insulin secretion in pancreatic β-cells under diabetes by reactivating the LDHA-lactate axisNature CommunicationsMarch 2, 2026Huige Lin, Melody Yuen Man Ho, Baomin Wang, Shama Mansoori, Yumei Yang, Wen Wang, Pui Kin So, Aimin Xu, Shilun Yang, Junlei Chang, et al.condition (2 mM glucose) and sequential injections of 20 mM glucose, 5 μM oligomycin (Cayman Chemical, Cat# 11341) and 50 μM 2-deoxy-D-glucose (2-DG; Cayman Chemical, Cat# 14325). The results were analyzed using Seahorse

(4) MRPL47 deficiency drives mitochondrial dysfunction via ROS-p38-p21 signaling in non-small cell lung cancerJournal of Biological ChemistryFebruary 1, 2026Nikita Bhandari, Yengkhom Ghanapriya Devi, Disha Acharya, Vinita Bhat, Annesha Chatterjee, Shweta Yalshetti, Sharathchandra Arandkar, Bal Krishna Chaube, Sudhanshu Shuklafollowed. First, a basal respiration was recorded and then sequential injections of Oligomycin (Cayman #11341), FCCP (Cayman #15218) and Antimycin A (CST #33357) was used to inhibit complexes I and III respectively.

(5) Tumor-derived RAC1A159V mutation promotes an immunosuppressive microenvironment that represses response to immune checkpoint inhibitorSci AdvOctober 31, 2025Mingjun Cai, Mike Adam, Xin Duan, Fukun Guo, Yi Zhengchallenged with 25 mM glucose (Sigma-Aldrich, catalog no. D8066), 10 μM oligomycin (Cayman, catalog no. 11341), and 100 mM 2-DG (Sigma-Aldrich, catalog no. D8375), allowing three measurements after each injection.

(6) Defective chaperone-mediated autophagy in the retinal pigment epithelium of age-related macular degeneration patientsEMBO Molecular MedicineOctober 30, 2025Juan Ignacio Jiménez-Loygorri, Peng Shang, Ibrahim Bayramoglu, Raquel Gómez-Sintes, Adrián Martín-Segura, Helena Ambrosino, Johnson Hoang, Antonio Díaz, Zhaohui Geng, Evripidis Gavathiotis, et al.and 1 mM sodium pyruvate (P5280, Merck) and subjected to sequential injections of 2 μM Oligomycin (11341, Cayman), 1 μM FCCP (15128, Cayman) and 1 μM Antimycin A+Rotenone (34799, 13995, Cayman). To assess

(7) Oxidative-stress-induced telomere instability drives T cell dysfunction in cancerImmunityOctober 14, 2025Dayana B. Rivadeneira, Sanjana Thosar, Kevin Quann, William G. Gunn, Victoria G. Dean, Bingxian Xie, Angelina Parise, Andrew C. McGovern, Kellie Spahr, Konstantinos Lontos, et al.Violet,ThermoFisher,Cat# C34571 L-glutamine,Fisher,Cat# MT25005CI Oligomycin Complex,Cayman Chemical,Cat# 11341 FCCP,Cayman Chemical,Cat# 15218 2-deoxy-D-glucose (2DG),Sigma,Cat# D8375-5G Rotenone,Sigma,Cat# R8875-5G Antimycin

(8) Reprogramming CD8+ T-cell Branched N- Glycosylation Limits Exhaustion, Enhancing Cytotoxicity and Tumor KillingCancer Immunology ResearchOctober 1, 2025Catarina M. Azevedo, Bingxian Xie, William G. Gunn, Ronal M. Peralta, Carolina S. Dantas, Henrique Fernandes-Mendes, Supriya Joshi, Victoria Dean, Pedro Almeida, Drew Wilfahrt, et al.Cell-Tak. The Seahorse Bioanalyzer then sequentially treated the cells with 2μM oligomycin (catalog number 11341, Cayman Chemical), 2μM FCCP (catalog number C-2920, Sigma), 10mM 2-deoxyglucose (catalog number NET328250UC,

(9) Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapyCell MetabolismApril 1, 2025Andrew T. Frisch, Yiyang Wang, Bingxian Xie, Aaron Yang, B. Rhodes Ford, Supriya Joshi, Katarzyna M. Kedziora, Ronal Peralta, Drew Wilfahrt, Steven J. Mullett, et al.Benzenetricarboxylic acid hydrate",Sigma-Aldrich,Cat# B4201 Oligomycin Complex,Cayman Chemical,Cat# 11341 FCCP,Cayman Chemical,Cat# 15218 "Seahorse media, RPMI no phenol red",Agilent,Cat# 103576–100 Glucose

(10) Inhibition of the PI3K-AKT-MTORC1 axis reduces the burden of the m.3243A>G mtDNA mutation by promoting mitophagy and improving mitochondrial functionAutophagyDecember 12, 2024Chih-Yao Chung, Kritarth Singh, Preethi Sheshadri, Gabriel E Valdebenito, Anitta R. Chacko, María Alicia Costa Besada, Xiao Fei Liang, Lida Kabir, Robert D. S. Pitceathly, Gyorgy Szabadkai, et al.bafilomycin A1 (Cayman Chemical 11038) was dissolved in DMSO for stock at 200 μM. Oligomycin (Cayman Chemical 11341) was in DMSO at 25 mM, Mdivi-1 (Sigma-Aldrich, M0199) was in DMSO at 50 mM and dichloroacetate (Sigma-Aldrich

(11) Transcriptional coactivator MED15 is required for beta cell maturationNature CommunicationsOctober 8, 2024Alex Z. Kadhim, Ben Vanderkruk, Samantha Mar, Meixia Dan, Katarina Zosel, Eric E. Xu, Rachel J. Spencer, Shugo Sasaki, Xuanjin Cheng, Shannon L. J. Sproul, et al.in Seahorse media during this time as follows: 16 mM Glucose, FCCP (# 15218), Oligomycin Complex (# 11341), and antimycin A (# 2247) + Rotenone (# 13995) (Cayman Chemical Company; Ann Arbor, MI, USA). The Seahorse

(12) PPARα Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in CounteractionClinical cancer research : an official journal of the American Association for Cancer ResearchMay 1, 2024Ross RB, Gadwa J, Yu J, Darragh LB, Knitz MW, Nguyen D, Olimpo NA, Abdelazeem KNM, Nguyen A, Corbo S, et al.oligomycin, rotenone and antimycin A). Additional reagents used included oligomycin (Cayman Chemical 11341), 2-deoxy-D-glucose (2-DG, Sigma-Aldrich D6134), and FCCP (Cayman Chemical 15218). Depending on the

(13) Hypoxia sensing requires H 2 S-dependent persulfidation of olfactory receptor 78Science AdvancesJuly 7, 2023Ying-Jie Peng, Jayasri Nanduri, Ning Wang, Ganesh K. Kumar, Vytautas Bindokas, Bindu D. Paul, Xuanmao Chen, Aaron P. Fox, Thibaut Vignane, Milos R. Filipovic, et al.application of 5 μM FCCP (Cayman Chemical, #15218) and oligomycin complex (20 μg/ml; Cayman Chemical, #11341) for 3 min at the end of each experiment. Only the cells exhibiting more than 20% changes in MMP in

(14) Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 lociBrain : a journal of neurologyDecember 19, 2022Soutar MPM, Melandri D, O'Callaghan B, Annuario E, Monaghan AE, Welsh NJ, D'Sa K, Guelfi S, Zhang D, Pittman A, et al.dx.doi.org/10.17504/protocols.io.eq2lyn1dqvx9/v1. Reagents Oligomycin (mitochondrial complex V inhibitor) was purchased from Cayman Chemicals (11341) and from Sigma-Aldrich (O4876), and antimycin A (mitochondrial complex III inhibitor) were purchased

(15) Proteomic Profiling Revealed Mitochondrial Dysfunction in Photoreceptor Cells under HyperglycemiaInternational journal of molecular sciencesNovember 1, 2022Lam CH, Cheung JK, Tse DY, Lam TC.equilibrium. The OCR was then measured under basal conditions, and after serial injection of 10 µM oligomycin (11341, Cayman Chemical, Ann Arbor, MI, USA), 100 µM carbonylcyanide-4-(trifluoro-methoxy) phenylhydrazone

(16) Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathwaysThe Journal of biological chemistrySeptember 1, 2022N'Gadjaga MD, Perrinet S, Connor MG, Bertolin G, Millot GA, Subtil A.follows: phenformin, 200 mM in H2O (Sigma-Aldrich, P7045); Oligomycin, 5 mM in DMSO (Cayman Chemical, 11341); GNE-140, 4 mM in DMSO (Sigma-Aldrich, SML2580). All chemicals were stored at −20 °C. Adhesion assay Adhesion

(17) Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responsesImmunityMay 11, 2021Xu K, Yin N, Peng M, Stamatiades EG, Chhangawala S, Shyu A, Li P, Zhang X, Do MH, Capistrano KJ, et al.(desiccated),BD,Cat. # 231141 Nicotinamide,Sigma Aldrich,Cat. # 72340-100G Oligomycin Complex,Cayman Chemical,Cat. # 11341-10MG 32% Paraformaldehyde Solution (EM Grade),Electron Microscopy Sciences,Cat. # 15714-S 100X Penicillin/Streptomycin

(18) Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial DysfunctionCancer researchSeptember 1, 2020Madala HR, Helenius IT, Zhou W, Mills E, Zhang Y, Liu Y, Metelo AM, Kelley ML, Punganuru S, Kim KB, et al.hemihydrochloride, C13408), and 3-bromopyruvate (16490), were purchased from Sigma Aldrich. Oligomycin (11341), necrostatin (11658), atpenin (11898), and metformin (13118) were purchased from Cayman Chemical. 3-NPA

(19) Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor ClearanceImmunitySeptember 17, 2019Rivadeneira DB, DePeaux K, Wang Y, Kulkarni A, Tabib T, Menk AV, Sampath P, Lafyatis R, Ferris RL, Sarkar SN, et al.systems,Cat# 498-OB-01M L-glutamine,Fisher,Cat# MT25005CI Oligomycin Complex,Cayman Chemical,Cat# 11341 FCCP,Cayman Chemical,Cat# 15218 2-deoxy-D-glucose (2DG),Sigma,Cat# D8375-5G Rotenone,Sigma,Cat# R8875-5G Antimycin

(20) Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil DifferentiationCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Tanimura A, Miyoshi K, Horiguchi T, Hagita H, Fujisawa K, Noma T.Minneapolis, MN) as IRE1α-XBP1 inhibitor. To inhibit mitochondrial ATP production, we used oligomycin (#11341; Cayman Chemical, Ann Arbor, MI). As a positive control, we applied 0.6 μg/ml of tunicamycin to the

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Oligomycin Complex from Cayman Chemical

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Cayman Chemical

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Oligomycin Complex from Cayman Chemical

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