Description
The vector of anti-BAFF-R chimeric antigen receptor (CAR) is constructed for the engineering of T cells to simultaneously target two epitopes of human BAFF-R. The T cells are genetically modified through transduction with a lentiviral vector expressing anti-BAFF-R VHH1 and VHH2 linked to CD28 and CD3ζ signaling domains. And the biepitope CAR targeting T cells can be used for the treatment of Stomach cancer