Description
The vector of anti-KCNN4 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target Human KCNN4. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-KCNN4 antibody linked to CD28 and CD3ζ signaling domains. And the vector product was designed for the treatment of Prostate cancer