Description
The vector of anti-CD3D chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target Human CD3D. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD3D antibody linked to CD28 and CD3ζ signaling domains. And the vector product was designed for the treatment of Acute myeloid leukemia (AML)