Human Coronavirus spike glycoprotein Gene ORF cDNA clone expression plasmid(Codon Optimized) from Sino Biological, Inc.

Product Specs
ItemHuman Coronavirus spike glycoprotein Gene ORF cDNA clone expression plasmid(Codon Optimized)
CompanySino Biological, Inc.
Price $445.00Supplier Page View Company Product Page
Catalog NumberVG40021-UT
Quantity1 Unit
Typeplasmid, cDNA-Clone
ApplicationsStable or Transient mammalian expression
Molecule NameSpike
SpeciesHCoV-HKU1

Sequence

A number of silent mutations were introduced into the DNA sequence in order to increase its protein expression level in mammalian cell system. The translated amino acid sequence is identical with YP_173238.1

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infectionNatureJuly 1, 2023Xu D, Jiang W, Wu L, Gaudet RG, Park ES, Su M, Cheppali SK, Cheemarla NR, Kumar P, Uchil PD, et al.Expression plasmids of the glycoproteins for HcoV-229E (VG40605-UT), HcoV-OC43 (VG40607-UT), HcoV-HKU1 (VG40021-UT) and EboV (VG40304-CF) were purchased from Sino Biological. pLV-EF1α-Flag-IRES-Hygro was modified from

(2) Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2iScienceApril 21, 2023Xie Q, Bozzo CP, Eiben L, Noettger S, Kmiec D, Nchioua R, Niemeyer D, Volcic M, Lee JH, Zech F, et al.202249", pCMV3-hCoV-OC43-spike-Flag,Sinobiological,VG40607-CF pCMV3-hCoV-HKU1-spike,Sinobiological,VG40021-UT pCG_MERS-CoV S (humanized) C-V5 IRES GFP,Michael Schindler, pCG_SARS-CoV-1 S (hum) C-V5 IRES GFP,Michael

(3) A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two dosesCell reportsOctober 25, 2022Tauzin A, Gong SY, Chatterjee D, Ding S, Painter MM, Goel RR, Beaudoin-Bussières G, Marchitto L, Boutin M, Laumaea A, et al.6029–1 pCG1-SARS-CoV-2 D614G-Spike,"(Beaudoin-Bussières et al., 2020)",N/A pCMV3-HCoV-HKU1-Spike,Sino Biological,Cat# VG40021-UT pCAGGS-SARS-CoV-2-B.1.617.2-Spike (Delta),"(Gong et al., 2021)",N/A pCAGGS-SARS-CoV-2-B.1.1.529-Spike

(4) Humoral immune responses against SARS-CoV-2 Spike variants after mRNA vaccination in solid organ transplant recipientsiScienceSeptember 16, 2022Tauzin A, Beaudoin-Bussières G, Gong SY, Chatterjee D, Gendron-Lepage G, Bourassa C, Goyette G, Racine N, Khrifi Z, Turgeon J, et al.6029–1 pCG1-SARS-CoV-2 D614G-Spike,"(Beaudoin-Bussières et al., 2020)",N/A pCMV3-HCoV-HKU1-Spike,Sino Biological,Cat# VG40021-UT pCAGGS-SARS-CoV-2-B.1.617.2-Spike (Delta),"(Gong et al., 2021)",N/A pCAGGS-SARS-CoV-2-B.1.1.529-Spike

(5) Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between dosesCell Host & MicrobeJanuary 12, 2022Alexandra Tauzin, Shang Yu Gong, Guillaume Beaudoin-BussiÃ¨res, Dani VÃ©zina, Romain Gasser, Lauriane Nault, Lorie Marchitto, Mehdi Benlarbi, Debashree Chatterjee, Manon Nayrac, et al.al., 2020)",N/A pcDNA3.1-MERS-CoV-S,"(Park et al., 2016)",N/A pCMV3-HCoV-HKU1-S,Sino Biological,Cat# VG40021-UT pCAGGS-SARS-CoV-2-B.1.1.7 S,"(Tauzin et al., 2021)",N/A pcDNA3.1-SARS-CoV-2-B.1.351 S,"(Gong et al.,

(6) Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacyImmunitySeptember 14, 2021Ullah I, Prévost J, Ladinsky MS, Stone H, Lu M, Anand SP, Beaudoin-Bussières G, Symmes K, Benlarbi M, Ding S, et al.2005)",N/A pCAGGS-OC43 Spike,"(Prévost et al., 2020)",N/A pCMV3-HKU1 Spike,Sino Biological,Cat # VG40021-UT pcDNA3.1-MERS-CoV Spike,"(Park et al., 2016)",N/A pαH-SARS-CoV-2 Spike HexaPro,"Dr Jason S. McLellan,

(7) A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responsesCell host & microbeJuly 14, 2021Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, et al.al., 2020)",N/A MERS-CoV Spike,"(Park et al., 2016)",N/A pCMV3-HCoV-HKU1 Spike,Sino Biological,Cat# VG40021-UT pcDNA3.1 SARS-CoV-2 Spike B.1.1.7,Genscript,N/A pCG1-SARS-CoV-2 Spike D614G/E484K,This paper,N/A pCG1-SARS-CoV-2

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