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Molecular Biology
DNA
AAV-pgk-Cre (AAV Retrograde)
AAV-pgk-Cre (AAV Retrograde) from Addgene Inc.
Be the first to write a review!
Citations:
(13)
Supplier Page
Supplier Page from
Addgene Inc. for
AAV-pgk-Cre (AAV Retrograde)
Description
Cre expression under the PGK promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
AAV-pgk-Cre (AAV Retrograde)
Company
Addgene Inc.
Price
Supplier Page
View Company Product Page
Catalog Number
24593-AAVrg
Quantity
100 µL
Sample Type
Ready-to-Use Retrograde AAV Prep
Source/Expression System
Mammalian
Purity
suitable purity for injection into animals
Species
recombinant adeno-associated virus (rAAV)
Molecule Name
Cre recombinase (codon optimized)
Nucleic Acid Type
Expression Vectors
Expression System (standardized)
Mammalian
Vector Type (Standardized)
AAV
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Addgene Inc.
490 Arsenal Way
Suite 100
Watertown
,
Massachusetts
02472
United States
Phone
: +1 (617) 233-4363
Email: help@addgene.org
Company Profile
Website:
www.addgene.org/
Citations (13)
(1)
Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1‐OSR1/SPAK‐Kv3.1 Cascade
The FASEB Journal
November 30, 2025
Xin Jin, Jian Xie, Chia‐Wei Yeh, Yu‐Jui Li, Cheng‐Chang Lien, Chou‐Long Huang
a humidified atmosphere of 5% CO2/95% air. The retrograde AAVrg‐cre
virus
was from
Addgene
(catalog
24593‐AAVrg
and
55632‐AAVrg
) [19, 20]. AAV2/5‐Cre‐EGFP was from the Viral Vector Core, University of Iowa. The following
(2)
Central Osmolality Sensing for Arginine Vasopressin Release Is Mediated by WNK1‐OSR1/SPAK‐Kv3.1 Cascade
FASEB J
November 17, 2025
Xin Jin, Jian Xie, Chia‐Wei Yeh, Yu‐Jui Li, Cheng‐Chang Lien, Chou‐Long Huang
a humidified atmosphere of 5% CO2/95% air. The retrograde AAVrg‐cre
virus
was from
Addgene
(catalog
24593‐AAVrg
and
55632‐AAVrg
) [19, 20]. AAV2/5‐Cre‐EGFP was from the Viral Vector Core, University of Iowa. The following
(3)
The mouse posterior insular cortex encodes expressive and receptive aspects of courtship vocalizations
Cell Reports
June 24, 2025
Thomas Pomberger, Katherine S. Kaplan, Rene Carter, Autumn Wetsel, Thomas C. Harmon, Richard Mooney
strains
,, AAV2/9-syn-jGCaMP8s-WPRE,Zhang et al. 202061,Cat#162374 Addgene AAVrg-PGK-Cre,Patrick Aebischer,Cat#
24593-AAVrg
Addgene
AAV-2/1-CAG-Flex-EGFP,Ian Wickersham,Cat#
59331-AAV1
Addgene
pENN.AAV.hsyn.Cre.WPRE.hGH,James
(4)
Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity
Nature Communications
November 24, 2024
Perla González-Pereyra, Oswaldo Sánchez-Lobato, Mario G. Martínez-Montalvo, Diana I. Ortega-Romero, Claudia I. Pérez-Díaz, Hugo Merchant, Luis A. Tellez, Pavel E. Rueda-Orozco
with a final volume of 1000 nl. AAV-pgk-Cre was a gift from Patrick Aebischer (
Addgene
viral prep #
24593-AAVrg
; http://n2t.net/addgene:24593; RRID:Addgene_24593). pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA
(5)
A hippocampus-accumbens code guides goal-directed appetitive behavior
Nature Communications
April 12, 2024
Oliver Barnstedt, Petra Mocellin, Stefan Remy
adeno-associated virus (AAV) under control of the polyglycokinase (pgk) promoter (AAVrg-pgk-Cre, Catalog #
24593-AAVrg
, titer: 1 × 1013 viral genomes (vg) ml−1,
Addgene
, Watertown, USA) in the NAc to enter
axons
and induce
(6)
WNK1 promotes water homeostasis by acting as a central osmolality sensor for arginine vasopressin release
The Journal of clinical investigation
June 1, 2023
Jin X, Xie J, Yeh CW, Chen JC, Cheng CJ, Lien CC, Huang CL.
metabolic cage experiments. Reagents. The AAVrg-cre retrograde
viruses
were from
Addgene
(catalog
24593-AAVrg
and
55632-AAVrg
) (54, 55). AAV2/5-EGFP and AAV-Cre were from the Viral Vector Core, University of Iowa.
(7)
Local targets of T-stellate cells in the ventral cochlear nucleus
The Journal of comparative neurology
November 1, 2022
Lin L, Campbell J, Oertel D, Smith PH.
surface of the brain. A total of 60–80 nl of AAV vector (rAAV2‐retro‐pkg‐Cre,
Addgene
(Watertown, MA)
24593‐AAVrg
; Tervo et al., 2016) or 400 nl of BDA (3000 MW, Invitrogen, 10% in sodium citrate‐HCl, pH = 3) was loaded
(8)
A miniature fluorescence microscope for multi-plane imaging
Scientific Reports
October 6, 2022
Giovanni Barbera, Rachel Jun, Yan Zhang, Bo Liang, Yun Li, Da-Ting Lin
C57BL/6 J male
mice
(age of 3–4 months,
body weight
~ 25 g) were injected with AAV-pgk-Cre (
Addgene
, #
24593-AAVrg
) into Nucleus Accumbens and pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (
Addgene
, #
104492-AAV1
) into prelimbic cortex
(9)
Activation of VIP interneurons in the prefrontal cortex ameliorates neuropathic pain aversiveness
Cell reports
September 13, 2022
Li M, Zhou H, Teng S, Yang G.
#
44361 -AAV9
AAV9-hSyn-DIO-mCherry,
Addgene
,Cat#
50459-AAV9
AAV8-CaMKIIα-hM3Dq-mCherry,
Addgene
,Cat#
50476-AAV8
AAV1-CaMKIIα-mCherry,
Addgene
,Cat#
114469-AAV1
AAVrg-Pgk-Cre,
Addgene
,Cat#
24593-AAVrg
AAV1-EF1a-FLPo,
Addgene
,Cat#
55637-AAV1
AAV1-EF1a-fDIO-mCherry,
Addgene
,Cat#
114471-AAV1
AAV5-CaMKIIα-EGFP,
Addgene
,Cat#
50469-AAV5
AAV1-CAG-FLEX-EGFP,
Addgene
,Cat#
51502-AAV1
,, Chemicals,Chemicals,Chemicals ,,
Clozapine N-oxide
(10)
Movement-specific signaling is differentially distributed across motor cortex layer 5 projection neuron classes
Cell Reports
May 10, 2022
Stephen P. Currie, Julian J. Ammer, Brian Premchand, Joshua Dacre, Yufei Wu, Constantinos Eleftheriou, Matt Colligan, Thomas Clarke, Leah Mitchell, A. Aldo Faisal,
et al.
custom-programmed LabVIEW-based software (LotoScan). For cell type specific imaging, AAV-pkg-Cre (
Addgene
24593-AAVrg
; 1.7x1013 GC/ml) was injected into either the ipsilateral (right) pons (PT; 0.4 mm lateral, 0.4 mm rostral
(11)
Harnessing rAAV-retro for gene manipulations in multiple pathways that are interrupted after spinal cord injury
Experimental neurology
April 1, 2022
Metcalfe M, Yee KM, Luo J, Martin-Thompson JH, Gandhi SP, Steward O.
produce
labeling
that is optimal for light sheet
microscopy
, we used rAAV2-retro/Cre (
Addgene
viral prep #
24593-AAVrg
) in transgenic RosatdTomato and PTENloxP/loxP /RosatdTomato
mice
[as in (Steward et al., 2021b)].
Procedures
(12)
Deletion of the clock gene Period2 (Per2) in glial cells alters mood-related behavior in mice
Scientific reports
June 10, 2021
Martini T, Ripperger JA, Stalin J, Kores A, Stumpe M, Albrecht U.
Sargsyan for technical support. AAV-pgk-Cre was a gift from Patrick Aebischer (
Addgene
viral prep #
24593-AAVrg
). This research was supported by the Swiss
National Science Foundation
(310030_184667/1). Author contributions Conceived
(13)
Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects
Nature Communications
December 1, 2019
Brendan D. Hare, Ryota Shinohara, Rong Jian Liu, Santosh Pothula, Ralph J. DiLeone, Ronald S. Duman
Research Foundation (NARSAD to B.D.H). AAV-pgk-Cre was a gift from Patrick Aebischer (
Addgene
viral prep #
24593-AAVrg
). AAV-hSyn-
DIO
-hM3D(Gq)-mCherry and AAV-hSyn-DIOmCherry were a gift from Bryan
Roth
(
Addgene
viral prep
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AAV-pgk-Cre (AAV Retrograde) from Addgene Inc.
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