Cultrex Spheroid Invasion Extracellular Matrix from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCultrex Spheroid Invasion Extracellular Matrix
CompanyR&D Systems, a Bio-Techne Brand
Price $301.00Supplier Page View Company Product Page
Catalog Number3500-096-03
Quantity6 mL
SpeciesMulti-Species
StorageProduct is stable for a minimum of 3 months from date of shipment. Store at –80 °C; keep frozen. Dispense into working aliquots if needed; repeated freeze-thaws will destroy product integrity

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Histone H4K8 lactylation promotes glioblastoma progression by inducing NUPR1-mediated autophagosome‒lysosome fusionTheranosticsFebruary 4, 2026Jiangli Zhao, Xuchen Liu, Yanya He, Qingyuan Sun, Zhiwei Xue, Ziyi Tang, Junzhi Liu, Jiwei Wang, Chao Li, Xinyu Wang, et al.plates to facilitate tumor sphere formation. Following sphere establishment, invasion gel (R&D Systems, #3500-096-03) was introduced, and the invasive capacity of the spheres was tracked for a period of 72 h. Wound healing

(2) Nuclear transport of phosphorylated LanCL2 promotes invadopodia formation and tumor progression of glioblastoma by activating STAT3/Cortactin signalingJournal of advanced researchMarch 1, 2025Zhao HF, Liu YS, Wang J, Wu CP, Zhou XM, Cai LR, Liu J, Liu XJ, Xu YW, Li WP, et al.

(3) Super-enhancer-driven SLCO4A1-AS1 is a new biomarker and a promising therapeutic target in glioblastomaScientific reportsJanuary 6, 2025Wu Y, Li F, Yang C, Zhang X, Xue Z, Sun Y, Lin X, Liu X, Zhao Z, Huang B, et al.transfected for 48 h were uniformly seeded into 96-well plates. After 24 h, invasion gel (R&D Systems; 3500-096-03; Minneapolis, MN, USA) was added into the wells and the diameter of the invasion range of the tumor

(4) Stimulation of tumoricidal immunity via bacteriotherapy inhibits glioblastoma relapseNature communicationsMay 18, 2024Zhang Y, Xi K, Fu Z, Zhang Y, Cheng B, Feng F, Dong Y, Fang Z, Zhang Y, Shen J, et al.into low-adherence 96-well plates. After sphere formation, the invasion gel (50 μL/well; R&D Systems; 3500–096-03; Minneapolis, MN, USA) was introduced, followed by a 72-hour incubation period. Throughout this timeframe,

(5) Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancerCancer LettersDecember 1, 2023Samrita Dogra, Sugantha Priya Elayapillai, Dongfeng Qu, Kamille Pitts, Alexander Filatenkov, Courtney W. Houchen, William L. Berry, Katherine Moxley, Bethany N. Hannafonsingle spheroid formation in each well. Culturex Spheroid Invasion Extracellular Matrix (R&D Systems, 3500-096-03) was added on top and allowed to polymerize for 1 hour at 37°C, followed by the addition of medium containing

(6) SLC25A32 promotes malignant progression of glioblastoma by activating PI3K-AKT signaling pathwayBMC cancerJune 26, 2023Xue Z, Wang J, Wang Z, Liu J, Zhao J, Liu X, Zhang Y, Liu G, Zhao Z, Li W, et al.adherence 96-well plates for 3D tumor sphere invasion tests. Invasion gel (50 µl/well; R&D Systems;3500-096-03; Minneapolis, MN, USA) was added to the wells after the creation of the spheres, and the plates were

(7) Cell senescence-associated genes predict the malignant characteristics of glioblastomaCancer cell internationalDecember 16, 2022Tan C, Wei Y, Ding X, Han C, Sun Z, Wang C.

(8) TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 proteinJournal of experimental & clinical cancer research : CRDecember 6, 2022Yang X, Zhang Y, Xue Z, Hu Y, Zhou W, Xue Z, Liu X, Liu G, Li W, Liu X, et al.seeded onto low adherence 96-well plates. After sphere formation, invasion gel (50 μ/well; R&D Systems; 3500–096-03; Minneapolis, MN, USA) was added to the wells, and plates were incubated for 72 h. Images were acquired

(9) Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasisNucleic acids researchAugust 12, 2022Mestre-Farràs N, Guerrero S, Bley N, Rivero E, Coll O, Borràs E, Sabidó E, Indacochea A, Casillas-Serra C, Järvelin AI, et al.

(10) Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cellsCancer communications (London, England)August 1, 2022Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, et al.to allow spheroid formation. After the spheroids formed, they were embedded in an invasion matrix (3500‐096‐03, R&D Systems) and supplemented with culture medium containing 25 μmol/L STO‐609 or DMSO at 37°C. The

(11) Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastomaCell death & diseaseApril 7, 2021Choi SW, Lee Y, Shin K, Koo H, Kim D, Sa JK, Cho HJ, Shin HM, Lee SJ, Kim H, et al.

(12) Tumor Treating Fields (TTFields) Hinder Cancer Cell Motility through Regulation of Microtubule and Acting DynamicsCancersOctober 17, 2020Voloshin T, Schneiderman RS, Volodin A, Shamir RR, Kaynan N, Zeevi E, Koren L, Klein-Goldberg A, Paz R, Giladi M, et al.

(13) DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traitsOncogeneSeptember 1, 2020Chi HC, Tsai CY, Wang CS, Yang HY, Lo CH, Wang WJ, Lee KF, Lai LY, Hong JH, Chang YF, et al.

(14) Low molecular weight heparin and direct oral anticoagulants influence tumour formation, growth, invasion and vascularisation by separate mechanismsScientific reportsApril 18, 2019Featherby S, Xiao YP, Ettelaie C, Nikitenko LL, Greenman J, Maraveyas A.

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