Fig 1: UCP2 induces PFKFB2 expression in AKT-dependent manner(i) Western blot analysis of AKT, pAKT, mTORC1, p-mTOR, p70S6K, p-p70S6K, 4EBP1, and p-4EBP1 in UCP2 overexpressed and control pCMV cells (A). (i) Western blots analysis of PFKFB2, pPFKFB2, AKT, and pAKT levels from UCP2 overexpressed cells treated with MK2206 (B). (iii) Western blots analysis of PFKFB2, pPFKFB2, AKT, and pAKT levels from UCP2 overexpressed cells treated with genipin (C).
from Cell Signaling Technology for p70 S6 Kinase MCF7 Control Cell Extracts