APE1 Redox Inhibitor from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemAPE1 Redox Inhibitor
CompanyNovus Biologicals, a Bio-Techne Brand
Price $199.00Supplier Page View Company Product Page
Catalog NumberNBP1-49581
FormatThis product is supplied as a powder. It is soluble in DMSO (>20 mg/mL)
StorageStore at -20C in powder form. Store at -80C once reconstituted
TargetAPE1 Redox
Quantity5 mg (also 10 mg, 25 mg)
CloneE3330

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) 8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injuryNucleic acids researchFebruary 22, 2023Pan L, Hao W, Xue Y, Wang K, Zheng X, Luo J, Ba X, Xiang Y, Qin X, Bergwik J, et al.

(2) Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cellsRedox biologyJuly 1, 2021Sriramajayam K, Peng D, Lu H, Zhou S, Bhat N, McDonald OG, Que J, Zaika A, El-Rifai W.Genetex (Irvine, CA, USA). The E3330, an APE1 redox inhibitor, was obtained from Novus Biologicals (NBP1-49581, Centennial, CO, USA) and GSK-3β inhibitors; lithium chloride (Calbiochem) and CHIR-98014 (Selleck chemicals).

(3) APE1 Upregulates MMP-14 via Redox-Sensitive ARF6-Mediated Recycling to Promote Cell Invasion of Esophageal AdenocarcinomaCancer researchSeptember 1, 2019Lu H, Bhat AA, Peng D, Chen Z, Zhu S, Hong J, Maacha S, Yan J, Robbins DJ, Washington MK, et al.

(4) Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisitedBiochemistryApril 30, 2013Zhang J, Luo M, Marasco D, Logsdon D, LaFavers KA, Chen Q, Reed A, Kelley MR, Gross ML, Georgiadis MM.

(5) Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell linesPloS oneJanuary 1, 2013Cesaratto L, Codarin E, Vascotto C, Leonardi A, Kelley MR, Tiribelli C, Tell G.

(6) Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonucleaseBiochemistryJanuary 17, 2012Luo M, Zhang J, He H, Su D, Chen Q, Gross ML, Kelley MR, Georgiadis MM.

(7) APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalPloS oneJanuary 1, 2012Cardoso AA, Jiang Y, Luo M, Reed AM, Shahda S, He Y, Maitra A, Kelley MR, Fishel ML.

(8) The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiationDNA repairSeptember 5, 2011Vasko MR, Guo C, Thompson EL, Kelley MR.

(9) Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growthMolecular cancer therapeuticsSeptember 1, 2011Fishel ML, Jiang Y, Rajeshkumar NV, Scandura G, Sinn AL, He Y, Shen C, Jones DR, Pollok KE, Ivan M, et al.

(10) Apurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophagesAnticancer researchFebruary 1, 2011Jedinak A, Dudhgaonkar S, Kelley MR, Sliva D.

(11) Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzymeBiochemistryJanuary 11, 2011Su D, Delaplane S, Luo M, Rempel DL, Vu B, Kelley MR, Gross ML, Georgiadis MM.

(12) Inhibition of APE1/Ref-1 redox activity with APX3330 blocks retinal angiogenesis in vitro and in vivoVision researchJanuary 1, 2011Jiang A, Gao H, Kelley MR, Qiao X.

(13) High-performance affinity beads for identifying anti-NF-kappa B drug receptorsMethods in enzymologyJanuary 1, 2002Hiramoto M, Shimizu N, Nishi T, Shima D, Aizawa S, Tanaka H, Hatakeyama M, Kawaguchi H, Handa H.

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