Description
Automated acquisition, analysis, and reporting for hands-free flow cytometry
Express Modes are a unique add-on for the MACSQuantify™ Software, developed to simplify flow cytometric analysis. They automate the measurement and analysis of flow experiments via predefined experiment settings as well as acquisition and automated analysis. A gating to your results will be automatically adjusted for each data file individually to achieve optimal results. Using the Express Modes simplifies flow cytometric analysis and ensures the reproducible data analysis.
T cells play a central role in the adaptive immune system by controlling a variety of immune responses. Recently, T cells have been redirected against cancer by genetic transduction with a receptor recognizing a specific tumor antigen and combined with intracellular co-stimulatory signaling domains. CD19 chimeric antigen receptor (CAR) T cells have shown tremendous clinical efficacy in treating patients with hematological malignancies. As part of the CAR T cell production process, multicolor flow cytometry is a suitable and easy method to identify and monitor CAR T cells. For standardization and automation of this analysis the CAR T Cell - Express Modes were developed.