Description
Cayman’s high-throughput screening (HTS) services offer fully automated compound screening backed by expertise in assay development and customization. As part of a medicinal chemistry or drug discovery program, our HTS services can aid in hit identification and lead discovery, validation of hits from virtual HTS, SAR studies, and hit-to-lead optimization.
Our scientists have combined the capabilities of the Agilent Bravo Automated Liquid Handler, Agilent BenchCel 4R Microplate Handler, and BioTek Synergy Neo2 Multimode Plate Reader to create a streamlined, fully automated HTS system that decreases run time, variability, and risk of user error, ensuring our customers get high-quality, accurate data with a shorter turnaround time and lower cost. Our system is compatible with a variety of assay formats and readouts, including:
- Colorimetric
- Fluorometric
- Luminescent
- HTR/TR-FRET
- AlphaScreen
- AlphaLISA
- Fluorescence Polarization
Customers can provide their own compound libraries for screening or choose from Cayman’s catalog of 30 unique, expertly curated screening libraries. We also offer custom compound library generation through our Chemical Synthesis Services division.