Description
It is reported that ZIKV E protein contains a unique positively charged patch to influence host attachment, and the Zika NS4A and NS4B proteins involve the microcephaly. The latest structural study of ZIKV NS5 methyltransferase (MTase) has shed light on the structure-based drug discovery against ZIKV. Mutations in NS5-MTase result in defects in N7 methylation that is lethal in flaviviruses, making NS5-MTase an attractive target to block cap formation. Creative Biostructure provides a comprehensive variety of professional research services targeting Zika virus to improve human health by developing novel antibodies and vaccines in therapeutic area. Please feel free to contact us for a detailed quote.