Description
Creative Bioarray strives to conduct custom reporter gene assays for your drug discovery. We are well-experienced in reporter genes construction using GFP and luciferase according to your specifications. We can also perform reporter gene assays with your own reporter gene constructs. Our reporter gene assays have been applied in identifying from ligands of target receptors such as G protein-coupled receptors (GPCR) to stimulators/inhibitors of entire signaling pathways such as insulin pathway. First, specific reporter genes are constructed and engineered cells are obtained. Then candidate compounds are added, and target gene or pathway activation are monitored by quantifying fluorescence. The readouts are technically simple and cost efficient and also amenable to HTS.