Description
Cyanation is a reaction in which a cyano group is attached or substituted on various substrates. Cyano groups is a strong electron-withdrawing group and many cyanides are widely used in organic synthesis. In addition, due to their unique properties, cyanides have important application value in the fields of perfumery, functional materials and pharmaceutical industry. For example, lemon nitrile is an international new type of nitrile spice and 4-Bromo-2, 6-difluoro benzonitrile is an important raw material for the preparation of liquid crystal materials. However, there are still some inadequacies for cyanation, such as olefin cyanide reactions, are more stringent and sometimes require the use of expensive catalysts for cyano addition.