Description
Carbon–hydrogen bond activation is used to replace hydrogen with carbon-X (X is usually carbon, oxygen or nitrogen) via C-H cleavage process which was first reported at 1955. C-H activation chemistry has paved novel way to transform the chemical synthesis through the conversion of cheap and abundant resource like alkanes, into valuable functionalized organic compounds or even the structural complex molecules. Also thanks to C-H activation, possible reaction has become available. This methodology has the potential to be used in many different areas of chemistry ranging from relatively small molecules like drug candidates, to complex polydisperse organic compounds such as polymers.