PP1α siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPP1α siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36299
Gene Nameprotein phosphatase 1, catalytic subunit, alpha isozyme
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein phosphatase 1 catalytic subunit alpha
NCBI Gene AliasesPP-1A, PP1A, PP1alpha, PPP1A
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The doxorubicin-induced cell motility network is under the control of the ceramide-activated protein phosphatase 1 alphaFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMarch 1, 2021Canals D, Salamone S, Santacreu BJ, Aguilar D, Hernandez-Corbacho MJ, Ostermeyer-Fay AG, Greene M, Nemeth E, Haley JD, Obeid LM, et al.for siRNA validation by western blot and for experiments. Small interfering DNA for PP1 alpha was sc-SC-36299 (Santa Cruz Biotechnology, Dallas, TX), PP1 beta: SC-36295, and PP1 gamma: sc-36297. Key results for

(2) Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK SignalingFrontiers in microbiologyJanuary 1, 2021Stecher C, Marinkov S, Mayr-Harting L, Katic A, Kastner MT, Rieder-Rommer FJJ, Lin X, Nekhai S, Steininger C.

(3) Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase IINature communicationsAugust 28, 2020Parua PK, Kalan S, Benjamin B, Sansó M, Fisher RP.fraction was prepared as described previously59. RNAi PP1 isoform-specific siRNAs targeting PP1α (sc-36299), PP1β (sc-36295), and PP1γ (sc-36297) were from Santa Cruz Biotechnology. For pan-PP1 depletion equimolar

(4) The role of dual‑specificity phosphatase 1 and protein phosphatase 1 in β2‑adrenergic receptor‑mediated inhibition of extracellular signal regulated kinase 1/2 in triple negative breast cancer cell linesMolecular medicine reportsJanuary 1, 2018Tuglu MM, Bostanabad SY, Ozyon G, Dalkiliç B, Gurdal H.

(5) Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancerNucleic acids researchApril 20, 2017Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, Zhang T, Russo J, Cai C, Yuan X, et al.M-003224-03; Cell Signaling, Cat. 3500S), PP1α siRNAs (Dharmacon, Cat. M-008927-00; Santa Cruz, Cat. Sc-36299); and AR siRNA (AR-1981, target sequence: AGGUUCUCUGCUAGACGACdTdT). The Flag-tagged AR-W741C-S650A(Ser650Ala)

(6) Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activationEMBO reportsMarch 1, 2017Hiraga SI, Ly T, Garzón J, Hořejší Z, Ohkubo YN, Endo A, Obuse C, Boulton SJ, Lamond AI, Donaldson AD.in this study Human RIF1 siRNA (Dharmacon, D‐027983‐02).Human PP1α siRNA (Santa Cruz Biotechnology, sc‐36299).Human PP1β siRNA (Santa Cruz Biotechnology, sc‐36295).Human PP1γ siRNA (Santa Cruz Biotechnology, sc‐36297).Control

(7) Ras Regulates Rb via NORE1AThe Journal of biological chemistryFebruary 5, 2016Barnoud T, Donninger H, Clark GJ.

(8) The role of LPA and YAP signaling in long-term migration of human ovarian cancer cellsCell communication and signaling : CCSApril 24, 2013Cai H, Xu Y.

(9) A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane trafficThe Journal of biological chemistryOctober 12, 2012Kloft N, Neukirch C, von Hoven G, Bobkiewicz W, Weis S, Boller K, Husmann M.

(10) Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1The Journal of biological chemistrySeptember 18, 2009Chen S, Kesler CT, Paschal BM, Balk SP.

(11) Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1Nature immunologyMay 1, 2008Li HY, Liu H, Wang CH, Zhang JY, Man JH, Gao YF, Zhang PJ, Li WH, Zhao J, Pan X, et al.

(12) Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processingHuman molecular geneticsJanuary 1, 2008Novoyatleva T, Heinrich B, Tang Y, Benderska N, Butchbach ME, Lorson CL, Lorson MA, Ben-Dov C, Fehlbaum P, Bracco L, et al.

(13) A PP1-binding motif present in BRCA1 plays a role in its DNA repair functionInternational journal of biological sciencesJanuary 1, 2008Yu YM, Pace SM, Allen SR, Deng CX, Hsu LC.

(14) Phorbol 12-myristate 13-acetate (PMA)-induced migration of glioblastoma cells is mediated via p38MAPK/Hsp27 pathwayBiochemical pharmacologySeptember 1, 2007Nomura N, Nomura M, Sugiyama K, Hamada J.

(15) Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye developmentThe Journal of biological chemistryMay 11, 2007Yan Q, Liu WB, Qin J, Liu J, Chen HG, Huang X, Chen L, Sun S, Deng M, Gong L, et al.

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PP1α siRNA (h)

PP1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PP1α siRNA (h) from Santa Cruz Biotechnology, Inc.

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