Cdk4 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCdk4 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29261
Gene Namecyclin-dependent kinase 4
Quantity10 µM
Specieshuman
NCBI Full Gene Namecyclin dependent kinase 4
NCBI Gene AliasesCMM3, PSK-J3
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90Scientific reportsOctober 22, 2021Zhao S, Zhou L, Dicker DT, Lev A, Zhang S, Ross E, El-Deiry WS.

(2) 4-Acetylantroquinonol B induced DNA damage response signaling and apoptosis via suppressing CDK2/CDK4 expression in triple negative breast cancer cellsToxicology and applied pharmacologyJuly 1, 2021Satriyo PB, Su CM, Ong JR, Huang WC, Fong IH, Lin CC, Aryandono T, Haryana SM, Deng L, Huang CC, et al.

(3) Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signalsGenes & developmentNovember 1, 2018Su Y, Pelz C, Huang T, Torkenczy K, Wang X, Cherry A, Daniel CJ, Liang J, Nan X, Dai MS, et al.(Santa Cruz Biotechnology, sc-106320), NUP98 (Thermo Fisher, AM1670), CDK4 (Santa Cruz Biotechnology, sc-29261), ERK (Cell Signaling Technology, 6560), CDK2 (Santa Cruz Biotechnology, sc-156139), MYC (Qiagen, SI00300902),

(4) Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 BindingMolecular cellDecember 21, 2017Liao P, Zeng SX, Zhou X, Chen T, Zhou F, Cao B, Jung JH, Del Sal G, Luo S, Lu H.84 SiRNA: SiCyclin D3-2,Sigma-Aldrich,SASI_Hs01_000501 85 SiRNA: SiCdk4(h),Santa Cruz Biotechnology,Cat# sc-29261 SiRNA: SiPin1(h),Santa Cruz Biotechnology,Cat# sc-36230 SiRNA: Sip53(h),Thermo Fisher,106141 SiRNA:

(5) Fluorescent peptide biosensor for monitoring CDK4/cyclin D kinase activity in melanoma cell extracts, mouse xenografts and skin biopsiesBiosensors & bioelectronicsNovember 15, 2016Prével C, Pellerano M, González-Vera JA, Henri P, Meunier L, Vollaire J, Josserand V, Morris MC.

(6) Transforming growth factor-β1 induces cell cycle arrest by activating atypical cyclin-dependent kinase 5 through up-regulation of Smad3-dependent p35 expression in human MCF10A mammary epithelial cellsBiochemical and biophysical research communicationsApril 8, 2016Park SJ, Yang SW, Kim BC.

(7) RNF4 regulates DNA double-strand break repair in a cell cycle-dependent mannerCell cycle (Georgetown, Tex.)January 1, 2016Kuo CY, Li X, Stark JM, Shih HM, Ann DK.RNF4, CDK2, CDK4 and CtIP were obtained from Santa Cruz Biotechnology (sc-38550, sc-38236, sc-29259, sc-29261 and sc-37765 respectively). Lipofectamine RNAiMAX (Invitrogen 13778150) was used for the siRNA transfections

(8) Cyclin-dependent kinase 4 may be expressed as multiple proteins and have functions that are independent of binding to CCND and RB and occur at the S and G 2/M phases of the cell cycleCell cycle (Georgetown, Tex.)November 15, 2013Sun Y, Lou X, Yang M, Yuan C, Ma L, Xie BK, Wu JM, Yang W, Shen SX, Xu N, et al.

(9) Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targetsScience signalingSeptember 24, 2013Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, et al.

(10) Black tea polyphenols induce human leukemic cell cycle arrest by inhibiting Akt signaling: possible involvement of Hsp90, Wnt/β-catenin signaling and FOXO1The FEBS journalAugust 1, 2012Halder B, Das Gupta S, Gomes A.

(11) Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cellsOncogenesisJune 4, 2012Shimura T, Noma N, Oikawa T, Ochiai Y, Kakuda S, Kuwahara Y, Takai Y, Takahashi A, Fukumoto M.

(12) Comparative proteome profiling of MCF10A and 184A1 human breast epithelial cells emphasized involvement of CDK4 and cyclin D3 in cell proliferationProteomics. Clinical applicationsJanuary 1, 2009Bhaskaran N, Lin KW, Gautier A, Woksepp H, Hellman U, Souchelnytskyi S.

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Cdk4 siRNA (h)

Cdk4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Cdk4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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