PKC ε siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPKC ε siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36251
Gene Nameprotein kinase C, epsilon
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein kinase C epsilon
NCBI Gene AliasesPKCE, nPKC-epsilon
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Association of Apolipoprotein E4-related Microvascular Disease in the Alzheimer’s Disease Hippocampal CA1 Stratum RadiatumNeuroscienceAugust 1, 2023Huaixing Wang, Zongxiu Zhang, Sorawit Sittirattanayeungyong, Jarin Hongpaisanknockdown was performed using 100 nM of three target-specific 19–25 nucleotide PKCε si-RNA constructs (sc-36251), purchased from Santa Cruz Biotechnology, Inc (Santa Cruz, CA, USA). For negative control, a scrambled

(2) I(KACh) is constitutively active via PKC epsilon in aging mediated atrial fibrillationiScienceNovember 18, 2022Chang M, Gada KD, Chidipi B, Tsalatsanis A, Gibbons J, Remily-Wood E, Logothetis DE, Oberstaller J, Noujaim SF.IMSR_JAX:004,189" ,, Oligonucleotides,Oligonucleotides,Oligonucleotides ,, PKC ε siRNA,Santa Cruz Biotechnology,Cat#sc-36251 ,, Recombinant DNA,Recombinant DNA,Recombinant DNA ,, mCherry-CRY2-PKCεCAT-HA,"Dr. Diomedes E. Logothetis,

(3) HIV Promotes Neurocognitive Impairment by Damaging the Hippocampal MicrovesselsMolecular neurobiologyAugust 1, 2022Sharma AL, Wang H, Zhang Z, Millien G, Tyagi M, Hongpaisan J.knockdown was performed using 100 nM of three target-specific 19–25 nucleotide PKCε si-RNA constructs (sc-36251), purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA, USA). For negative control, a scrambled

(4) The FGFR2c/PKCε Axis Controls MCL-1-Mediated Invasion in Pancreatic Ductal Adenocarcinoma Cells: Perspectives for Innovative Target TherapiesBiomedicinesJuly 9, 2022Ranieri D, French D, Persechino F, Guttieri L, Torrisi MR, Belleudi F.

(5) Role of FGFR2c and Its PKCε Downstream Signaling in the Control of EMT and Autophagy in Pancreatic Ductal Adenocarcinoma CellsCancersOctober 5, 2021Ranieri D, Guttieri L, Raffa S, Torrisi MR, Belleudi F.

(6) Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer CellsMolecules and cellsAugust 31, 2021Yoon S, Shin B, Woo HG.Santa Cruz Biotechnology), siATF2 (catalog No. sc-29205; Santa Cruz Biotechnology) or siPKCε (catalog No. sc-36251; Santa Cruz Biotechnology). The siRNAs were transfected into liver cancer cells using Lipofectamine 3000

(7) The aberrant expression in epithelial cells of the mesenchymal isoform of FGFR2 controls the negative crosstalk between EMT and autophagyJournal of cellular and molecular medicineApril 1, 2021Ranieri D, Nanni M, Guttieri L, Torrisi MR, Belleudi F.

(8) Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switchCell communication and signaling : CCSMay 19, 2020Ranieri D, Nanni M, Persechino F, Torrisi MR, Belleudi F.with PKCε small interfering RNA (PKCε siRNA) (Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA; sc36251), ESRP1 siRNA (Santa Cruz Biotechnology, SC77526), or an unrelated siRNA as a control, using Lipofectamine 2000 transfection reagent

(9) CYP1B1 prevents proteasome-mediated XIAP degradation by inducing PKCε activation and phosphorylation of XIAPBiochimica et biophysica acta. Molecular cell researchDecember 1, 2019Baek HS, Kwon YJ, Ye DJ, Cho E, Kwon TU, Chun YJ.

(10) Impact of PKCε downregulation on autophagy in glioblastoma cellsBMC cancerFebruary 13, 2018Toton E, Romaniuk A, Konieczna N, Hofmann J, Barciszewski J, Rybczynska M.

(11) PKCε Increases Extracellular Elastin and Fibulin-5/DANCE in Dermal FibroblastsCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Nishizaki T.

(12) Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease HippocampusJournal of Alzheimer's disease : JADJanuary 1, 2018Sen A, Nelson TJ, Alkon DL, Hongpaisan J.

(13) Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Cε/Nrf2/HO-1 PathwayMolecular neurobiologyMarch 1, 2017Guo C, Wang S, Duan J, Jia N, Zhu Y, Ding Y, Guan Y, Wei G, Yin Y, Xi M, et al.

(14) Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKCNeurobiology of diseaseOctober 1, 2016Do Van B, Gouel F, Jonneaux A, Timmerman K, Gelé P, Pétrault M, Bastide M, Laloux C, Moreau C, Bordet R, et al.

(15) PKCε inhibits isolation and stemness of side population cells via the suppression of ABCB1 transporter and PI3K/Akt, MAPK/ERK signaling in renal cell carcinoma cell line 769PCancer lettersJune 28, 2016Huang B, Fu SJ, Fan WZ, Wang ZH, Chen ZB, Guo SJ, Chen JX, Qiu SP.

(16) Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistanceCancer lettersMay 28, 2015Miklos W, Pelivan K, Kowol CR, Pirker C, Dornetshuber-Fleiss R, Spitzwieser M, Englinger B, van Schoonhoven S, Cichna-Markl M, Koellensperger G, et al.

(17) ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear TranslocationThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 13, 2015Sen A, Nelson TJ, Alkon DL.

(18) Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase CBritish journal of pharmacologyMarch 1, 2014Illing S, Mann A, Schulz S.

(19) PKCε promotes HuD-mediated neprilysin mRNA stability and enhances neprilysin-induced Aβ degradation in brain neuronsPloS oneJanuary 1, 2014Lim CS, Alkon DL.

(20) Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethalityCancer cellFebruary 11, 2013Sourbier C, Scroggins BT, Ratnayake R, Prince TL, Lee S, Lee MJ, Nagy PL, Lee YH, Trepel JB, Beutler JA, et al.