PPARγ siRNA (h) from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Free Cholesterol‐Induced Liver Injury in Non‐Alcoholic Fatty Liver Disease: Mechanisms and a Therapeutic Intervention Using Dihydrotanshinone IAdvanced ScienceNovember 19, 2024Jia‐Wen Shou, Juncai Ma, Xuchu Wang, Xiao‐Xiao Li, Shu‐Cheng Chen, Byung‐Ho Kang, Pang‐Chui Shaw(sc‐37007, Santa Cruz), Pparα siRNA (human: sc‐36307; mouse: sc‐36308; Santa Cruz), Pparγ siRNA (human: sc‐29455; mouse: sc‐29456; Santa Cruz) or Pparδ siRNA (human: sc‐36305; mouse: sc‐36306) was carried out using

(2) The Activation of PPARγ by (2Z,4E,6E)-2-methoxyocta-2,4,6-trienoic Acid Counteracts the Epithelial-Mesenchymal Transition Process in Skin CarcinogenesisCellsMarch 24, 2023Flori E, Mosca S, Cardinali G, Briganti S, Ottaviani M, Kovacs D, Manni I, Truglio M, Mastrofrancesco A, Zaccarini M, et al.was from Biobasic Canada Inc. (Markham, ON, Canada). Non-specific siRNA (sc-37007) and PPARγ siRNA (sc-29455) were from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The Amaxa human keratinocyte Nucleofector kit

(4) Qihuang Zhuyu Formula Attenuates Atherosclerosis via Targeting PPARγ to Regulate Cholesterol Efflux and Endothelial Cell InflammationOxidative medicine and cellular longevityJanuary 1, 2022Wang M, Xiang Q, Sun W, Zhang H, Shi R, Guo J, Tong H, Fan M, Ding Y, Shi H, et al.cell medium (ECM, 1001) was obtained from ScienCell (San Diego, USA). Human PPARγ siRNA (si-PPARγ, sc-29455) and mouse si-PPARγ (sc-29456) were obtained from Santa Cruz Biotechnology (Santa Cruz, USA). Transfection reagent

(5) PPARγ attenuates hepatic inflammation and oxidative stress of non‑alcoholic steatohepatitis via modulating the miR‑21‑5p/SFRP5 pathwayMolecular medicine reportsNovember 1, 2021Zhang X, Deng F, Zhang Y, Zhang X, Chen J, Jiang Y.confluence of HepG2 cells was 70%, small interfering RNA (siRNA) against PPARγ mRNA (100 nm; cat. no. sc-29455) and NC siRNA (100 nm; scrambled siRNA, sc-37007; both Santa Cruz Biotechnology) were transfected into

(6) Tectorigenin alleviates intrahepatic cholestasis by inhibiting hepatic inflammation and bile accumulation via activation of PPARγBritish journal of pharmacologyJune 1, 2021Xiang J, Yang G, Ma C, Wei L, Wu H, Zhang W, Tao X, Jiang L, Liang Z, Kang L, et al.

(7) Anti-influenza A Virus Effects and Mechanisms of Emodin and Its Analogs via Regulating PPARα/γ-AMPK-SIRT1 Pathway and Fatty Acid MetabolismBioMed research internationalJanuary 1, 2021Bei Y, Tia B, Li Y, Guo Y, Deng S, Huang R, Zeng H, Li R, Wang GF, Dai J.semiquantified by ImageJ software. 2.8. RNA Interfering Assay Human PPARα siRNA (sc-36307), PPARγ siRNA (sc-29455), AMPKα1 siRNA (sc-45312), and scrambled siRNA (sc-37007) were purchased from Santa Cruz Biotechnology Inc

(11) Peroxisome Proliferator-Activated Receptor-γ Knockdown Impairs Bone Morphogenetic Protein-2-Induced Critical-Size Bone Defect RepairThe American journal of pathologyMarch 1, 2019Wang C, Tanjaya J, Shen J, Lee S, Bisht B, Pan HC, Pang S, Zhang Y, Berthiaume EA, Chen E, et al.

(12) Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and LScientific reportsJanuary 24, 2019Saidi A, Kasabova M, Vanderlynden L, Wartenberg M, Kara-Ali GH, Marc D, Lecaille F, Lalmanach G.system). Inhibition of PPARγ expression by siRNA or pharmacological inhibition PPARγ small interfering RNA (siPPARγ, SC-29455) or scrambled control siRNA (siScr, SC-37007) were obtained from Santa Cruz. CCD-19Lu cells were seeded

(14) Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJuly 1, 2018Han M, Gao H, Ju P, Gao MQ, Yuan YP, Chen XH, Liu KL, Han YT, Han ZW.

(16) Insulin downregulates C3 gene expression in human HepG2 cells through activation of PPARγEuropean journal of cell biologyApril 1, 2018Shavva VS, Bogomolova AM, Efremov AM, Trofimov AN, Nikitin AA, Babina AV, Nekrasova EV, Dizhe EB, Oleinikova GN, Missyul BV, et al.

(19) Anticancer properties of 4-thiazolidinone derivatives depend on peroxisome proliferator-activated receptor gamma (PPARγ)European journal of medicinal chemistryDecember 1, 2017Szychowski KA, Leja ML, Kaminskyy DV, Kryshchyshyn AP, Binduga UE, Pinyazhko OR, Lesyk RB, Tobiasz J, Gmiński J.