c-Src siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemc-Src siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29859
Gene Namev-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Speciesmouse
NCBI Full Gene NameRous sarcoma oncogene
NCBI Gene Aliasespp60c-src
TypesiRNA/dsRNA
Quantity10 µM

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Tumor Suppressor DAPK1 Catalyzes Adhesion Assembly on Rigid but Anoikis on Soft MatricesFrontiers in cell and developmental biologyJanuary 1, 2022Qin R, Melamed S, Yang B, Saxena M, Sheetz MP, Wolfenson H.

(2) Toll-Like Receptor 4 Mediated Oxidized Low-Density Lipoprotein-Induced Foam Cell Formation in Vascular Smooth Muscle Cells via Src and Sirt1/3 PathwayMediators of inflammationJanuary 1, 2021Chen Z, Xue Q, Cao L, Wang Y, Chen Y, Zhang X, Xiao F, Yang Y, Hayden MR, Liu Y, et al.(Cat#13778150) were purchased from Invitrogen (CA, USA). Tlr4 siRNA (Cat#sc-40261), Src siRNA (Cat#sc-29859), and negative control siRNA (Cat#sc-37007) were bought from Santa Cruz (TX, USA). Let-blank (Cat#GCNL),

(3) c-Src kinase impairs the expression of mitochondrial OXPHOS complexes in liver cancerCellular signallingAugust 1, 2020Hunter CA, Koc H, Koc EC.

(4) Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophyNature communicationsSeptember 19, 2019Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Noda S, Murakami A, Onodera K, Okada Y, et al.p130Cas siRNA (sc-36142) (Santa Cruz Biotechnology, Texas, USA). To knockdown Src, we used c-Src siRNAs (sc-29859) (Santa Cruz Biotechnology). We used the Stealth RNAi negative control duplex (Invitrogen) as the control

(5) Neural Cell Adhesion Molecule 2 (NCAM2)-Induced c-Src-Dependent Propagation of Submembrane Ca2+ Spikes Along Dendrites Inhibits Synapse MaturationCerebral cortex (New York, N.Y. : 1991)April 1, 2019Sheng L, Leshchyns'ka I, Sytnyk V.

(6) 17β-estradiol Induces MMP-9 and MMP-13 in TMJ Fibrochondrocytes via Estrogen Receptor αJournal of dental researchAugust 1, 2018Ahmad N, Chen S, Wang W, Kapila S.transcription factor (ELK-1), or p65 nuclear factor kappa B (NF-κB; a major unit of NF-κB) or control siRNAs (sc-29859, sc-3529, sc-29411, and sc-37007; Santa Cruz Biotech) or treated with the following signaling inhibitors:

(7) The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infectionScience signalingJanuary 3, 2017Li X, Yang M, Yu Z, Tang S, Wang L, Cao X, Chen T.

(8) Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent Protein Kinase (PKR), Inducible Nitric Oxide Synthase (iNOS), and Src ProteinThe Journal of biological chemistryJuly 15, 2016Zhang L, Xiang W, Wang G, Yan Z, Zhu Z, Guo Z, Sengupta R, Chen AF, Loughran PA, Lu B, et al.

(9) c-Src tyrosine kinase mediates high glucose-induced endothelin-1 expressionThe international journal of biochemistry & cell biologyJune 1, 2016Manea SA, Fenyo IM, Manea A.

(10) Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signalingOncotargetMay 31, 2016Li JT, Wang WQ, Wang L, Liu NN, Zhao YL, Zhu XS, Liu QQ, Gao CF, Yang AG, Jia LT.(siRNA) duplexes corresponding to mouse TLR2 (sc-40257), TLR4 (sc-40261), MyD88 (sc-35987), c-Src (sc-29859), p47phox (sc-151963), p38 MAPK (sc-29434), NF-κB p65 (sc-29411), iNOS (sc-36092), NMDA receptor subunit

(11) Mitochondrial events responsible for morphine's cardioprotection against ischemia/reperfusion injuryToxicology and applied pharmacologyJanuary 1, 2016He H, Huh J, Wang H, Kang Y, Lou J, Xu Z.

(12) Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levelsThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 28, 2015Sheng L, Leshchyns'ka I, Sytnyk V.quantification. Cortical neurons were used for live siRNAs designed to knock down expression of mouse c-Src (sc-29859), cell imaging at 24 –72 h after transfection. Unless indicated otherwise, CaMKII␣ (sc-29901), or CaMKII␤

(13) Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survivalAmerican journal of physiology. Endocrinology and metabolismJuly 1, 2014Ke K, Sul OJ, Choi EK, Safdar AM, Kim ES, Choi HS.

(14) LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lungAmerican journal of physiology. Lung cellular and molecular physiologyJune 15, 2013Barabutis N, Handa V, Dimitropoulou C, Rafikov R, Snead C, Kumar S, Joshi A, Thangjam G, Fulton D, Black SM, et al.

(15) TLR3-triggered reactive oxygen species contribute to inflammatory responses by activating signal transducer and activator of transcription-1Journal of immunology (Baltimore, Md. : 1950)June 15, 2013Yang CS, Kim JJ, Lee SJ, Hwang JH, Lee CH, Lee MS, Jo EK.

(16) Hydroquinone regulates hemeoxygenase-1 expression via modulation of Src kinase activity through thiolation of cysteine residuesFree radical biology & medicineApril 1, 2013Byeon SE, Yu T, Yang Y, Lee YG, Kim JH, Oh J, Jeong HY, Hong S, Yoo BC, Cho WJ, et al.

(17) Dual inhibition of Src and GSK3 maintains mouse embryonic stem cells, whose differentiation is mechanically regulated by Src signalingStem CellsJuly 1, 2012Shimizu T, Ueda J, Ho JC, Iwasaki K, Poellinger L, Harada I, Sawada Y.

(18) Histone deacetylase-3 activation promotes tumor necrosis factor-alpha (TNF-alpha) expression in cardiomyocytes during lipopolysaccharide stimulationThe Journal of biological chemistryMarch 26, 2010Zhu H, Shan L, Schiller PW, Mai A, Peng T.

(19) A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cellsBloodOctober 8, 2009Yi Z, Li L, Matsushima GK, Earp HS, Wang B, Tisch R.

(20) Alveolar macrophages from septic mice promote polymorphonuclear leukocyte transendothelial migration via an endothelial cell Src kinase/NADPH oxidase pathwayJournal of immunology (Baltimore, Md. : 1950)December 15, 2008Wang Z, Rui T, Yang M, Valiyeva F, Kvietys PR.

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c-Src siRNA (m)

c-Src siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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c-Src siRNA (m) from Santa Cruz Biotechnology, Inc.

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