Chk1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemChk1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29269
Gene NameCHK1 checkpoint homolog (S. pombe)
Quantity10 µM
Specieshuman
NCBI Full Gene Namecheckpoint kinase 1
NCBI Gene AliasesCHK1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ATR signalling mediates the prosurvival function of phospho-NPM against PIDDosome mediated cell deathCellular signallingJuly 1, 2020Hiregange D, Naick H, Rao BJ.

(2) Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 DownregulationInternational journal of molecular sciencesApril 13, 2020Choi C, Cho WK, Park S, Shin SW, Park W, Kim H, Choi DH.Santa Cruz Biotechnology (Santa Cruz, CA, USA). For gene knockdown experiments, control siRNA (sc-37007), CHK1 siRNA (sc-29269), and Rad51 siRNA (sc-36361) were purchased from Santa Cruz Biotechnology. RNAiMax was purchased from Invitrogen

(3) Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cellsExperimental & molecular medicineAugust 14, 2018He L, Zhu H, Zhou S, Wu T, Wu H, Yang H, Mao H, SekharKathera C, Janardhan A, Edick AM, et al.

(4) Camptothecin induces G(2)/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen speciesOncotargetApril 24, 2018Prasad Tharanga Jayasooriya RG, Dilshara MG, Neelaka Molagoda IM, Park C, Park SR, Lee S, Choi YH, Kim GY.

(5) Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradationGenes & cancerJanuary 1, 2018Shen T, Zhou H, Shang C, Luo Y, Wu Y, Huang S.

(6) The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cellsJournal of ovarian researchSeptember 12, 2017Zhang R, Shi H, Ren F, Zhang M, Ji P, Wang W, Liu C.

(7) Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cellsCancer biology & therapyNovember 1, 2016Rahal ON, Fatfat M, Hankache C, Osman B, Khalife H, Machaca K, Muhtasib HG.

(8) Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell lineOncology reportsNovember 1, 2014Ling H, Lu LF, He J, Xiao GH, Jiang H, Su Q.

(9) STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferationProceedings of the National Academy of Sciences of the United States of AmericaApril 1, 2014Koganti S, Hui-Yuen J, McAllister S, Gardner B, Grasser F, Palendira U, Tangye SG, Freeman AF, Bhaduri-McIntosh S.test. Transfections. EBV-LCL were transfected with 100 μM siRNA [targeting STAT3 (sc-29493), Chk1 (sc-29269), scrambled (sc-37007), or FITC-scrambled (sc36869); Santa Cruz Biotechnology] as described (25). In

(10) Gain of cellular adaptation due to prolonged p53 impairment leads to functional switchover from p53 to p73 during DNA damage in acute myeloid leukemia cellsThe Journal of biological chemistryOctober 22, 2010Chakraborty J, Banerjee S, Ray P, Hossain DMS, Bhattacharyya S, Adhikary A, Chattopadhyay S, Das T, Sa G.

(11) Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cellsThe international journal of biochemistry & cell biologyFebruary 1, 2010Peralta-Sastre A, Manguan-Garcia C, de Luis A, Belda-Iniesta C, Moreno S, Perona R, Sanchez-Perez I.

(12) Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cellsCancer researchJuly 15, 2008Gali-Muhtasib H, Kuester D, Mawrin C, Bajbouj K, Diestel A, Ocker M, Habold C, Foltzer-Jourdainne C, Schoenfeld P, Peters B, et al.

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Chk1 siRNA (h)

Chk1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Chk1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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