IKKα siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIKKα siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29365
Gene Nameconserved helix-loop-helix ubiquitous kinase
Quantity10 µM
Specieshuman
NCBI Full Gene Namecomponent of inhibitor of nuclear factor kappa B kinase complex
NCBI Gene AliasesBPS2, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Sesamol Attenuates Renal Inflammation and Arrests Reactive-Oxygen-Species-Mediated IL-1β Secretion via the HO-1-Induced Inhibition of the IKKα/NFκB Pathway In Vivo and In VitroAntioxidants (Basel, Switzerland)December 14, 2022Tseng KF, Tsai PH, Wang JS, Chen FY, Shen MY.

(2) CORM-2 prevents human gingival fibroblasts from lipoteichoic acid-induced VCAM-1 and ICAM-1 expression by inhibiting TLR2/MyD88/TRAF6/PI3K/Akt/ROS/NF-κB signaling pathwayBiochemical pharmacologyJuly 1, 2022Cheng CY, Chen YH, Thuy Tien Vo T, Chui Hong Y, Wang CS, Canh Vo Q, Chou HC, Huang TW, Lee IT.

(3) Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis via Inhibition of Oxidative Stress/IKKα/p53Antioxidants (Basel, Switzerland)September 24, 2021Wang JS, Tsai PH, Tseng KF, Chen FY, Yang WC, Shen MY.

(4) IL-17A-associated IKK-α signaling induced TSLP production in epithelial cells of COPD patientsExperimental & molecular medicineOctober 5, 2018Anzalone G, Albano GD, Montalbano AM, Riccobono L, Bonanno A, Gagliardo R, Bucchieri F, Marchese R, Moscato M, Profita M.

(5) Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapyPloS oneJanuary 1, 2018Uddin MM, Zou Y, Sharma T, Gatla HR, Vancurova I.was measured by using Trypan Blue exclusion. Transfection with siRNA Human IL-8 (sc-39631), IKKα (sc-29365), IKKβ (sc-35644), IKKε (sc-39056), and non-silencing (sc-37007) small interfering RNAs (siRNAs) were

(6) Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical PathwaysFrontiers in oncologyJanuary 1, 2018Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, et al.

(7) VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1The Journal of cell biologyMarch 6, 2017Labrousse-Arias D, Martínez-Alonso E, Corral-Escariz M, Bienes-Martínez R, Berridy J, Serrano-Oviedo L, Conde E, García-Bermejo ML, Giménez-Bachs JM, Salinas-Sánchez AS, et al.(sc-35316), vhl (sc-36816), phd1 (sc-45616), phd2 (sc-45537), phd3 (sc-45799), nik (sc-36065), ikkα (sc-29365), p52 (sc-29409), and p50 (sc-29407) or with a nontargeted pool of control scrambled siRNAs (sc-37007)

(8) IL-17A induces chromatin remodeling promoting IL-8 release in bronchial epithelial cells: Effect of TiotropiumLife sciencesMay 1, 2016Anzalone G, Gagliardo R, Bucchieri F, Albano GD, Siena L, Montalbano AM, Bonanno A, Riccobono L, Pieper MP, Gjomarkaj M, et al.

(9) Plumbagin Suppresses the Invasion of HER2-Overexpressing Breast Cancer Cells through Inhibition of IKKα-Mediated NF-κB ActivationPloS oneJanuary 1, 2016Kawiak A, Domachowska A.

(10) Anticancer drug bortezomib increases interleukin-8 expression in human monocytesBiochemical and biophysical research communicationsMay 1, 2015Sanacora S, Urdinez J, Chang TP, Vancurova I.nmol (final concentration) of control siRNA-A (sc-37007; Santa Cruz Biotechnology, CA, USA), IKKα (sc-29365), IKKβ (sc-35644), or p38 siRNA (sc-29433) were used. Cells were transfected with TransITsiQUEST transfection reagent

(11) Ang II-AT1R increases cell migration through PI3K/AKT and NF-κB pathways in breast cancerJournal of cellular physiologyNovember 1, 2014Zhao Y, Wang H, Li X, Cao M, Lu H, Meng Q, Pang H, Li H, Nadolny C, Dong X, et al.

(12) Proteasome inhibition by bortezomib increases IL-8 expression in androgen-independent prostate cancer cells: the role of IKKαJournal of immunology (Baltimore, Md. : 1950)September 1, 2013Manna S, Singha B, Phyo SA, Gatla HR, Chang TP, Sanacora S, Ramaswami S, Vancurova I.mRNA were purchased from SA Biosciences (Frederick, MD, USA). Transfection with siRNA Human IKKα (sc- 29365), IKKβ (sc-35644), IKKε/i RNA (sc-39056), IκBα (sc-29360) and non-silencing control (sc-37007) small

(13) EMT and CSC-like properties mediated by the IKKβ/IκBα/RelA signal pathway via the transcriptional regulator, Snail, are involved in the arsenite-induced neoplastic transformation of human keratinocytesArchives of toxicologyJune 1, 2013Jiang R, Li Y, Xu Y, Zhou Y, Pang Y, Shen L, Zhao Y, Zhang J, Zhou J, Wang X, et al.

(14) A subset of IL-17(+) mesenchymal stem cells possesses anti-Candida albicans effectCell researchJanuary 1, 2013Yang R, Liu Y, Kelk P, Qu C, Akiyama K, Chen C, Atsuta I, Chen W, Zhou Y, Shi S.of IKKα by siRNA to block IκBα degradation (inhibition of NFκB-mediated gene expression; IKKα siRNA: sc-29365, Santa Cruz Biotechnology, Santa Cruz, CA, USA) also blocked IL17-induced downregulation of TGF-β1 in

(15) Mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by cyclosporin aThe Journal of biological chemistryFebruary 10, 2012Rudloff I, Bachmann M, Pfeilschifter J, Mühl H.

(16) IκB kinase-driven nuclear factor-κB activation in patients with asthma and chronic obstructive pulmonary diseaseThe Journal of allergy and clinical immunologySeptember 1, 2011Gagliardo R, Chanez P, Profita M, Bonanno A, Albano GD, Montalbano AM, Pompeo F, Gagliardo C, Merendino AM, Gjomarkaj M.

(17) Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cellsOncogeneOctober 2, 2008Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, et al.Double-stranded siRNAs to IKKa and IKKb were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) (sc-29365, sc-35644) and transfected with OligoFectamine (Invitrogen, Carlsbad, CA, USA). For these experiments,

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IKKα siRNA (h)

IKKα siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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IKKα siRNA (h) from Santa Cruz Biotechnology, Inc.

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