IKKβ siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIKKβ siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35644
Gene Nameinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Quantity10 µM
Specieshuman
NCBI Full Gene Nameinhibitor of nuclear factor kappa B kinase subunit beta
NCBI Gene AliasesIKK-beta, IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The REDD1–NF-κB–miRNAs–eNOS/SIRT1 axis mediates obesity-induced endothelial cell senescence and hypertensionNature CommunicationsMarch 12, 2026Yoon Kyung Choi, Dong-Keon Lee, Minsik Park, Junyoung Byeon, Woo-Young Nam, Thuy Linh Lai, Kyu Nam Kim, Okhwa Kim, Sungwoo Ryoo, Jeong-Hyung Lee, et al.siRNAs (80 nM, control siRNA, #sc-37007; human REDD1, #sc-45806; mouse Redd1, #sc-45807; human IKKβ, #sc-35644; human NF-κB p65, #sc-29410; mouse NF-κB p65, #sc-29411; human Raptor, #44069; human DICER, #sc40489;

(2) CORM-2 prevents human gingival fibroblasts from lipoteichoic acid-induced VCAM-1 and ICAM-1 expression by inhibiting TLR2/MyD88/TRAF6/PI3K/Akt/ROS/NF-κB signaling pathwayBiochemical pharmacologyJuly 1, 2022Cheng CY, Chen YH, Thuy Tien Vo T, Chui Hong Y, Wang CS, Canh Vo Q, Chou HC, Huang TW, Lee IT.

(3) TNF-α elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p-dependent down-regulation of cGMP-dependent kinase 1The Journal of biological chemistrySeptember 21, 2018Choi S, Park M, Kim J, Park W, Kim S, Lee DK, Hwang JY, Choe J, Won MH, Ryoo S, et al.

(4) Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapyPloS oneJanuary 1, 2018Uddin MM, Zou Y, Sharma T, Gatla HR, Vancurova I.using Trypan Blue exclusion. Transfection with siRNA Human IL-8 (sc-39631), IKKα (sc-29365), IKKβ (sc-35644), IKKε (sc-39056), and non-silencing (sc-37007) small interfering RNAs (siRNAs) were obtained from Santa Cruz Biotechnology

(5) Activation of TWIST1 by COL11A1 promotes chemoresistance and inhibits apoptosis in ovarian cancer cells by modulating NF-κB-mediated IKKβ expressionInternational journal of cancerDecember 1, 2017Wu YH, Huang YF, Chang TH, Chou CY.

(6) BM microenvironmental protection of CML cells from imatinib through Stat5/NF-κB signaling and reversal by WogoninOncotargetApril 26, 2016Xu X, Zhang X, Liu Y, Yang L, Huang S, Lu L, Wang S, Guo Q, Zhao L.

(7) Plumbagin Suppresses the Invasion of HER2-Overexpressing Breast Cancer Cells through Inhibition of IKKα-Mediated NF-κB ActivationPloS oneJanuary 1, 2016Kawiak A, Domachowska A.

(8) Activin A expression in esophageal carcinoma and its association with tumor aggressiveness and differentiationOncology LettersJuly 1, 2015ZHENHUA WANG, NING ZHANG, RUIFENG SONG, RUITAI FAN, LIUQIN YANG, LIPING WU10% goat serum for 30 min at 37˚C and then incubated with mouse anti‑human activin A antibody (1:100; sc-35644; Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA) at 4˚C overnight. After washing three times in

(9) Anticancer drug bortezomib increases interleukin-8 expression in human monocytesBiochemical and biophysical research communicationsMay 1, 2015Sanacora S, Urdinez J, Chang TP, Vancurova I.concentration) of control siRNA-A (sc-37007; Santa Cruz Biotechnology, CA, USA), IKKα (sc-29365), IKKβ (sc-35644), or p38 siRNA (sc-29433) were used. Cells were transfected with TransITsiQUEST transfection reagent

(10) Ang II-AT1R increases cell migration through PI3K/AKT and NF-κB pathways in breast cancerJournal of cellular physiologyNovember 1, 2014Zhao Y, Wang H, Li X, Cao M, Lu H, Meng Q, Pang H, Li H, Nadolny C, Dong X, et al.

(11) HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitinationCell death & diseaseMay 15, 2014Li T, Guan J, Li S, Zhang X, Zheng X.constructed by Shanghai Genechem Corporation (Shanghai, China). siRNA of NEMO (sc-29363) and IKKβ (sc-35644) were from Santa Cruz (Dallas, TX, USA). The sequences of the sense strand of USP7 shRNA was 5′-ACCCUUGGACAAUAUUCCU-3′

(12) (E)-2,4-Bis(p-hydroxyphenyl)-2-butenal inhibits tumor growth via suppression of NF-κB and induction of death receptor 6Apoptosis : an international journal on programmed cell deathJanuary 1, 2014Ban JO, Jung YS, Kim DH, Park KR, Yun HM, Lee NJ, Lee HP, Shim JH, Jeong HS, Lee YH, et al.

(13) Proteasome inhibition by bortezomib increases IL-8 expression in androgen-independent prostate cancer cells: the role of IKKαJournal of immunology (Baltimore, Md. : 1950)September 1, 2013Manna S, Singha B, Phyo SA, Gatla HR, Chang TP, Sanacora S, Ramaswami S, Vancurova I.purchased from SA Biosciences (Frederick, MD, USA). Transfection with siRNA Human IKKα (sc- 29365), IKKβ (sc-35644), IKKε/i RNA (sc-39056), IκBα (sc-29360) and non-silencing control (sc-37007) small interfering RNAs

(14) EMT and CSC-like properties mediated by the IKKβ/IκBα/RelA signal pathway via the transcriptional regulator, Snail, are involved in the arsenite-induced neoplastic transformation of human keratinocytesArchives of toxicologyJune 1, 2013Jiang R, Li Y, Xu Y, Zhou Y, Pang Y, Shen L, Zhao Y, Zhang J, Zhou J, Wang X, et al.

(15) Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatinCellular signallingJune 1, 2013Valente AJ, Yoshida T, Izadpanah R, Delafontaine P, Siebenlist U, Chandrasekar B.

(16) Mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by cyclosporin aThe Journal of biological chemistryFebruary 10, 2012Rudloff I, Bachmann M, Pfeilschifter J, Mühl H.

(17) Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cellsOncogeneOctober 2, 2008Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, et al.siRNAs to IKKa and IKKb were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) (sc-29365, sc-35644) and transfected with OligoFectamine (Invitrogen, Carlsbad, CA, USA). For these experiments, control

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IKKβ siRNA (h)

IKKβ siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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IKKβ siRNA (h) from Santa Cruz Biotechnology, Inc.

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