SignalSilence ® Stat3 siRNA II from Cell Signaling Technology

Product Specs
ItemSignalSilence ® Stat3 siRNA II
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6582S
Quantity300 µl
TargetSTAT3
NCBI Gene AliasesADMIO, ADMIO1, APRF, HIES
NCBI Full Gene Namesignal transducer and activator of transcription 3
Research AreaMAP Kinase Signaling
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) WNT5A drives interleukin-6-dependent epithelial-mesenchymal transition via the JAK/STAT pathway in keloid pathogenesisBurns & traumaJanuary 1, 2022Lee YI, Shim JE, Kim J, Lee WJ, Kim JW, Nam KH, Lee JH.(D-001810-10-05; Dharmacon, Lafayette, CO, USA), siWNT5A (L-003939-00-0005; Dharmacon) or siSTAT3 (6582S; Cell Signaling Technology, Danvers, MA, USA) for 24 h using Lipofectamine (Invitrogen, Carlsbad, CA,

(2) Synergistic Effect of Bazedoxifene and PARP Inhibitor in the Treatment of Ovarian Cancer Regardless of BRCA MutationAnticancer ResearchMay 1, 2021RUIJIE ZHANG, TIFFANY WANG, JIAYUH LINin 96-well plates with 4,000 cells per well and transfected with GP130 siRNA (Cell Signaling Technology, #6582s) or negative control siRNA (Cell Signaling Technology, #6568s) at a final concentration of 50 nM using

(3) Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancerOncogeneJune 1, 2018Reebye V, Huang KW, Lin V, Jarvis S, Cutilas P, Dorman S, Ciriello S, Andrikakou P, Voutila J, Saetrom P, et al.

(4) Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse modelBrainFebruary 1, 2018Chad A Tagge et al.

(5) Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Modulation of STAT3-CCL2 SignalingInternational Journal of Molecular SciencesJuly 25, 2017Sung-Ying Huang, Shu-Fang Chang, Kuan-Fu Liao, Sheng-Chun Chiuwas shown as clear areas in the gel. 4.8. Small Interfering RNA (siRNA) Transfection STAT3 siRNA (#6582) was purchased from Cell Signaling Technology, Inc., (Danvers, MA, USA). Non-targeting siRNA (ON-TARGET

(6) Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis inductionBMC cancerMarch 24, 2016Huang JS, Yao CJ, Chuang SE, Yeh CT, Lee LM, Chen RM, Chao WJ, Whang-Peng J, Lai GM.software. Knockdown of STAT3 STAT3 siRNA was purchased from Cell Signaling (SignalSilence® Stat3 siRNA II #6582). The mismatch siRNA oligonucleotide 5′-UCGGCUCUUACGCAUUCAA-3′ was used as a siRNA control. Cells were

(7) Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathwayOncology reportsDecember 1, 2015Wu L, Guo L, Liang Y, Liu X, Jiang L, Wang L.factors used in the present study were: N2 supplement (Gibco), FGF, EGF (R&D Systems), and STAT3 siRNA (#6582; CST). Cell viability and clonogenic assay. For cell viability assay, 8x10 4 cells were seeded into

(8) Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibitionThe ProstateSeptember 1, 2015Liu C, Lou W, Armstrong C, Zhu Y, Evans CP, Gao AC.at a density of 1×105 cells per well in 12-well plates and transfected with siRNA (Cell signaling #6582) targeting the Stat3 sequence; a control sequence targeting the luciferase (Luc) gene, siControl (5’-CTTACGCTGAGTACTTCGA-3’),

(9) Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered ProteinsJournal of Chemical Information and ModelingMay 26, 2015Wei Ye, Dingjue Ji, Wei Wang, Ray Luo, Hai-Feng ChenIakoucheva LM, Obradovic ZK. Intrinsic Disorder and Protein Function. Biochemistry-US. 2002; 41:6573–6582. 8. Iakoucheva LM, Brown CJ, Lawson JD, Obradović Z, Dunker AK. Intrinsic Disorder in CellSignaling

(10) Postulated Mechanisms of Resistance of B-Cell Non-Hodgkin Lymphoma to Rituximab Treatment Regimens: Strategies to Overcome ResistanceSeminars in OncologyDecember 3, 2014Benjamin BonavidaChemo/Immuno-sensitization of Drug-Resistant B-NHL Is Independent of Its Fc Functions. Clin Cancer Res. 2009; 15:6582–94. [PubMed: 19861448] 34. Alas S, Bonavida B. Inhibition of constitutive STAT3 activity sensitizes

(11) Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cellsThe ProstateFebruary 1, 2014Liu C, Zhu Y, Lou W, Cui Y, Evans CP, Gao AC.at a density of 1×105 cells per well in 12-well plates and transfected with siRNA (Cell Signaling #6582) targeting Stat3 and a control siRNA targeting the luciferase (Luc) gene, using Lipofectamine-RNAiMAX

(12) Properties and nature of Be starsAstronomy & AstrophysicsJanuary 1, 2012J. NemravovÃ¡, P. Harmanec, P. KoubskÃ½, A. Miroshnichenko, S. Yang, M. Å lechta, C. Buil, D. KorÄÃ¡kovÃ¡, V. Votrubaof spectra Ond Rit OHP DAO OHP/Cst 4 55398.4531 3 55100.3285 54533.2727 2 53745.5116 53258.5126 1 52730.5717 0 -1 6532 6542 6552 6562 6572 6582 6592 wavelength[A] Fig. 1. Recent evolution of the Hα line profile. Mid-exposure times of the displayed

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