SignalSilence ® FoxO3a siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® FoxO3a siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6302S
Quantity300 µl
TargetFoxO3a
NCBI Gene AliasesAF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A
NCBI Full Gene Nameforkhead box O3
Research AreaPI3K / Akt Signaling
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Cryopreservation Induces Acetylation of Metabolism-Related Proteins in Boar SpermInternational Journal of Molecular SciencesJuly 1, 2023Malik Ahsan Ali, Ziyue Qin, Shan Dou, Anqi Huang, Yihan Wang, Xiang Yuan, Yan Zhang, Qingyong Ni, Rameesha Azmat, Changjun ZengMDH2 antibody 1:1000, # 8610, Cell Signaling Technology, Shanghai, China; Anti-LDH-C mAB 1:1000, # 6302, PTM BIO; SIRT5 polyclonal antibody 1:2000, # PA5-31029, Invitrogen) overnight at 4 °C. All the antibodies

(2) The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus ReplicationmBioAugust 30, 2022Hongbo Zhang, Anthony J. Domma, Felicia D. Goodrum, Nathaniel J. Moorman, Jeremy P. Kamil(Cell Signaling Technology; catalog no. 6242), and SignalSilence FoxO3a siRNA I (Cell Signaling Technology; catalog no. 6302). RNA was extracted from HFFs at the indicated time points using the RNeasy minikit (Qiagen, Hilden,

(3) Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4Redox biologyJune 1, 2022Ying KE, Feng W, Ying WZ, Li X, Xing D, Sun Y, Chen Y, Sanders PW.SignalSilence® FoxO1 siRNA I (Cat# 6242, Cell Signaling Technology, Danvers, MA), and SignalSilence® FoxO3a siRNA I (Cat# 6302, Cell Signaling Technology, Danvers, MA); Trilencer-27 universal scrambled negative siRNA (Cat# SR30004,

(4) Loss of ULK1 Attenuates Cholesterogenic Gene Expression in Mammalian Hepatic CellsFrontiers in Cell and Developmental BiologySeptember 30, 2020Sangam Rajak, Liliana F. Iannucci, Jin Zhou, B. Anjum, Nelson George, Brijesh K. Singh, Sujoy Ghosh, Paul M. Yen, Rohit A. SinhaScientific, s62452), Becn1 (Thermo Fisher Scientific, s80166), FoxO3a (Cell Signaling Technology, #6302) siRNA (10 nM) for 48 or 72 h, followed by harvesting cells for RNA or protein extraction. ULK1 inhibitor

(5) Downregulated FOXO3a Associates With Poor Prognosis and Promotes Cell Invasion and Migration via WNT/β-catenin Signaling in Cervical CarcinomaFrontiers in OncologyJune 16, 2020Yuejun Tian, Ping Qi, Xuemei Hucultured in DMEM supplemented with 1% antibiotics and 10% FBS. FOXO3a SignalSilence siRNAs (Cat. No 6302S; Cell Signaling Technology, USA) were purchased to knock down FOXO3a expression. The pCMV6-FOXO3a (Cat.

(6) Downregulation of FOXO3a by DNMT1 promotes breast cancer stem cell properties and tumorigenesisCell death and differentiationMarch 1, 2020Liu H, Song Y, Qiu H, Liu Y, Luo K, Yi Y, Jiang G, Lu M, Zhang Z, Yin J, et al.expression. RNA interference and plasmid transfection FOXO3a siRNAs (SignalSilence® FOXO3a siRNA I, Cat. No 6302; SignalSilence® FoxO3a siRNA II, Cat. No 6303) were purchased from Cell Signaling Technology (Denvers,

(7) Fractional Anisotropy Brain Changes in Spasticity after Peripheral Injections of BotulinInternational Journal of PhysiatryDecember 31, 2018Bertoni Miguel Angel, Sakel Mohammed, Hojjatoleslami Alitransformed variables were 833 for CC and on the affected side 203 for CST, 972 for FL, 783 for PL, 6302 for TL and 1143 for OL. The mean values of post injection transformed variables on the contralateral

(8) Aflatoxin B1 Promotes Influenza Replication and Increases Virus Related Lung Damage via Activation of TLR4 SignalingFrontiers in ImmunologyOctober 4, 2018Yuhang Sun, Jiarui Su, Zixuan Liu, Dandan Liu, Fang Gan, Xingxiang Chen, Kehe Huang

(9) Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammationScientific reportsSeptember 19, 2017Wang Z, Guo S, Wang J, Shen Y, Zhang J, Wu Q.

(10) An evolutionarily conserved pathway controls proteasome homeostasisNatureAugust 11, 2016Rousseau A, Bertolotti A.

(11) A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activityNature communicationsAugust 26, 2015Conde-Perez A, Gros G, Longvert C, Pedersen M, Petit V, Aktary Z, Viros A, Gesbert F, Delmas V, Rambow F, et al.Cell Signaling, 9336), S6 (Cell Signaling, 2317), pS6 (Ser235/236) (Cell Signaling, 4857), β-catenin (Abcam, ab-6302), pβ-catenin (Ser675, Cell Signaling, 4176), pβ-catenin (Ser33-37/Thr41, Cell Signaling, 9561), pβ-catenin

(12) Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinaseGenes & developmentJuly 1, 2014Zheng X, Zhai B, Koivunen P, Shin SJ, Lu G, Liu J, Geisen C, Chakraborty AA, Moslehi JJ, Smalley DM, et al.Dharmacon (catalog no. D0012100220). FOXO3a siRNA was obtained from Cell Signaling Technology (catalog no. 6302). EglN2 (1) and EglN2 (4) siRNAs were described previously (Zhang et al. 2009): USP9x si1 target sequence,

(13) Performance-enhanced mesenchymal stem cells via intracellular delivery of steroidsScientific reportsApril 10, 2014Ankrum JA, Dastidar RG, Ong JF, Levy O, Karp JM.media (Invitrogen), and gently mixed. 20 μl of SignalSilence FOXO3 siRNA (Cell Signaling Technology, #6302S) or scramble control siRNA (Cell Signaling Technology, #6201S) per sample was diluted into 0.5 ml of

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