SignalSilence ® Atg7 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® Atg7 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6604S
Quantity300 µl
TargetATG7
NCBI Gene AliasesAPG7-LIKE, APG7L, GSA7, SCAR31
NCBI Full Gene Nameautophagy related 7
Research AreaAutophagy
TypesiRNA
ApplicationssiRNA
ReactivityH

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) REV1‑targeting inhibitor JH‑RE‑06 induces ferroptosis via NCOA4‑mediated ferritinophagy in colorectal cancer cellsOncology ReportsSeptember 22, 2025Jianhua Cheng, Xiaoxia Yang, Wen Zhao, Jie Xu, Yanjie Hao, Fang Xu5 min. A total of 15 µl small interfering (si) RNA [ATG7 (Autophagy-related gene 7) RNA I (cat. no. 6604, Cell Signaling Technology, Inc., sequences not available), NCOA4-targeting and scramble siRNA (sequences

(2) ATG10S promotes IFNL1 expression and autophagic degradation of multiple viral proteins mediated by IFNL1AutophagyOctober 1, 2024Zhang MQ, Li JR, Yang L, Peng ZG, Wu S, Zhang JP.were separately transfected into cells at a concentration of 5 nM for 30 h. The ATG7-specific siRNA (6604) and its corresponding negative control siRNA (6568) were obtained from Cell Signaling Technology, and

(3) Activation of lysosomal mediated cell death in the course of autophagy by mTORC1 inhibitorScientific ReportsDecember 1, 2022Sameer Ullah Khan et al.(#8540S), p70S6K (#9205, #9234P), p4EBP (#9455P, #2855P), anti-p62 antibody (#5114, #8025S), ATG7 siRNA (#6604), ATG5 siRNA (#6345), Beclin-1 siRNA (#6222), beclin-1antibody (#3495S), Caspase-3 (#9662S) Sigma-Aldrich:

(4) Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTORCell death & diseaseJuly 12, 2022Lee B, Park SJ, Lee S, Lee J, Lee E, Yoo ES, Chung WS, Sohn JW, Oh BC, Kim S.overnight, and then siRNAs were added for 48 h. For knock-down experiments, siATG7 (SignalSilence #6604; Cell Signaling Technology), siBeclin-1 (SignalSilence #6222; Cell Signaling Technology), siAMPK (siAMPK

(5) Inhibitory Effect of Etravirine, a Non-Nucleoside Reverse Transcriptase Inhibitor, via Anterior Gradient Protein 2 Homolog Degradation against Ovarian Cancer MetastasisInternational journal of molecular sciencesJanuary 15, 2022Ly TTG, Yun J, Ha JS, Kim YJ, Jang WB, Van Le TH, Rethineswaran VK, Choi J, Kim JH, Min SH, et al.Santa Cruz Biotechnology (Dallas, TX, USA). Antibodies against cleaved caspase-3 (Asp175, 9664), ATG7 siRNA (6604S), ULK1 (8054S), and PCNA (D3H8P, 13110) antibodies were purchased from Cell Signaling Technology (Boston,

(6) p62 Overexpression Promotes Bone Metastasis of Lung Adenocarcinoma out of LC3-Dependent AutophagyFrontiers in OncologyMay 21, 2021Dongqi Li, Chuanchun He, Fan Ye, En Ye, Hao He, Gong Chen, Jing ZhangAtg7 knockout (Atg-/-) by siRNA was purchased from Cell Signaling Technology, Inc., GER (cat. no. #6604). Transfections of SPC-A-1 and A549 cells with siRNA (50 nm) were performed using a Lipofectamine® 3000

(7) Cell Signaling in Hepatocellular CarcinomaAmerican Research Journal of BiosciencesNovember 5, 2020Mahmoud Balbaa, Yasmin R. Shahina, Nihal M. Elguindycorresponding author (Fax: +20 3 3911794; E-mail: mahmoud.balbaa@alexu.edu.eg, http://orcid.org/0000-0002-0876-6604). # ABSTRACT Cell signaling pathways are important for cellular communications and control different

(8) Activation of autophagy during farnesyl pyrophosphate synthase inhibition is mediated through PI3K/AKT/mTOR signalingJournal of International Medical ResearchApril 1, 2020Jie Han, Chaoyang Huang, Jiukun Jiang, Dongmei Jiangexpression The siRNA for Atg7 was obtained from Cell Signaling Technology (SignalSilence® Atg7 siRNA I #6604). HUVECs were transfected with the specific siRNA using Lipofectamine 2000 (Thermo Fisher Scientific).

(9) Zidovudine-Mediated Autophagy Inhibition Enhances Mitochondrial Toxicity in Muscle CellsAntimicrobial Agents and ChemotherapyJanuary 1, 2019H. Lin, M. V. Stankov, J. Hegermann, R. Budida, D. Panayotova-Dimitrova, R. E. Schmidt, G. M. N. Behrens32). siRNA-mediated knockdown. C2C12 cells were transfected with ATG7-speciﬁc siRNA (catalog number 6604; Cell Signaling) for 72 h per the manufacturer’s instructions, before treatment with the respective

(10) Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1Nature immunologyFebruary 1, 2018Garber C, Vasek MJ, Vollmer LL, Sun T, Jiang X, Klein RS.

(11) 5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cellsCell Death DiscoveryDecember 1, 2017Vilma Dembitz, Hrvoje Lalic, Dora VisnjicControl (#6568), SignalSilence Beclin 1 siRNA I (#6222) and II (#6246), SignalSilence Atg7 siRNA I (#6604) were purchased from Cell Signaling Technology. ON-TARGETplus SMARTpool Human ATG7 (L-020112-00), PIK3C3

(12) AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cellsOncotargetSeptember 15, 2017Song Y, Zhang P, Sun Y, Li X, Chen L, Xiao Y, Xing Y.FITC Annexin V Apoptosis Detection Kit I came from BD biosciences (#556547, Franklin Lakes, NJ, USA). ATG7 siRNA I (6604S) and control siRNA (6568S) were products of Cell Signaling Technology (Beverly, MA, USA). Antibodies

(13) Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErKFrontiers in NeuroscienceAugust 3, 2017Olalekan M. Ogundele, Fernando A. Rosa, Rohan Dharmakumar, Charles C. Lee, Joseph Francis

(14) Prominent differences in left ventricular performance and myocardial properties between right ventricular and left ventricular-based pacing modes in ratsScientific reportsJuly 19, 2017Mulla W, Etzion S, Elyagon S, Gillis R, Murninkas M, Konstantino Y, Mannhardt I, Eschenhagen T, Liel-Cohen N, Etzion Y.

(15) Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem CellsAging and diseaseMay 1, 2017Long Q, Luo Q, Wang K, Bates A, Shetty AK.

(16) Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injuryNature communicationsDecember 19, 2016Jablonska B, Gierdalski M, Chew LJ, Hawley T, Catron M, Lichauco A, Cabrera-Luque J, Yuen T, Rowitch D, Gallo V.

(17) Role of CaMKII in Ang-II-dependent small artery remodelingVascular pharmacologyDecember 1, 2016Prasad AM, Ketsawatsomkron P, Nuno DW, Koval OM, Dibbern ME, Venema AN, Sigmund CD, Lamping KG, Grumbach IM.

(18) Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survivalOncogeneNovember 10, 2016S Joshi, S Kumar, M P Ponnusamy, S K Batrasequence10 and commercially available siRNA oligonucleotides (Cell Signaling Technology, Catalog no. 6604S, Boston, MA, USA), respectively, by using Lipofectamine 2000 (Invitrogen) according to the manufacturer’s

(19) Enhanced autophagy in colorectal cancer stem cells does not contribute to radio-resistanceOncotargetJuly 19, 2016Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Chang-Ying Guo, Hanako Doi, Kaio Kitazato, Tao-Sheng Liperformed using a FACSCalibur instrument (Becton Dickinson). RNA interference siRNA specific to ATG7 (#6604S) and a control siRNA (#6568S) were obtained from SignalSilence (Cell Signaling Technology, Inc.). We

(20) Extracellular DNA traps released by acute promyelocytic leukemia cells through autophagyCell Death & DiseaseJune 1, 2016R Ma et al.manufacturer's instructions.52 siRNA transfection NB4 cells were transiently transfected with Atg7 siRNA (no. 6604; Cell Signaling Technology, Danvers, MA, USA) at a concentration of 100 nM using Lipofectamine RNAiMAX Transfection Reagent

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