SignalSilence ® KEAP1 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® KEAP1 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number5285S
Quantity300 µl
TargetKEAP1
NCBI Gene AliasesINrf2, KLHL19
NCBI Full Gene Namekelch like ECH associated protein 1
Research AreaUbiquitin and Ubiquitin-like proteins
ReactivityH
ApplicationssiRNA
TypesiRNA

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) 4′-Demethylpodophyllotoxin functions as a mechanism-driven therapy by targeting the PI3K-AKT pathway in Colorectal cancerTranslational OncologyJanuary 1, 2025Jun Liu, Dandong Luo, Xiaochuan Chen, Jiaqi Liu, Junxiong Chen, Mengchen Shi, Haiyan Dong, Yucheng Xu, Xinyou Wang, Zhaoliang Yu, et al.USA), AKT (9272, Cell Signaling Technology, USA), γ-H2A (2577, Cell Signaling Technology, USA), WEE1 (5285, Santa Cruze Biotechnology, USA), RAD51(398,587, Santa Cruze Biotechnology, USA) and β-Actin (4967,

(2) DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damageCell SystemsApril 17, 2024Joshua L. Justice, Tavis J. Reed, Brett Phelan, Todd M. Greco, Josiah E. Hutton, Ileana M. CristeaICP0 (Virusys #B1550114); α-p53 Ac-K382 (Cell Signaling #2525S) used 1:500; α-tubulin (Santa Cruz #5285); α-GAPDH (Cell Signaling #5174S); α-Mouse IgG-Alexa Fluor 800 (Life Technologies #A32730); and α-Rabbit

(3) Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer TherapyCancersSeptember 1, 2022Saha S, Rundle S, Kotsopoulos IC, Begbie J, Howarth R, Pappworth IY, Mukhopadhyay A, Kucukmetin A, Marchbank KJ, Curtin N.Ab3114; 1:500), Ku80 (Abcam, Ab80592; 1:500), PARP1 (Biovision, 3001-100; 1:500), WEE1 (Santa-Cruz, 5285 1:500). ATR, CHK1 and WEE1 activity and inhibition was estimated by measuring pCHK1S345 (Cell Signalling,

(4) Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathwaysJournal of ginseng researchJuly 1, 2022Xu C, Li L, Wang C, Jiang J, Li L, Zhu L, Jin S, Jin Z, Lee JJ, Li G, et al.μM) for 10 min. 2.14 siRNA transfection After transfection with 100 nM siAKT (#6909; CST), siNrf2 (#5285; CST), sip 65 (#6337; CST) or siControl (#6568; CST) for 48 h, RBL-2H3 cells were collected for further

(5) Different Susceptibilities of Human Melanoma Cell Lines to G2/M Blockage and Cell Death Activation in Response to the Estrogen Receptor β agonist LY500307Journal of CancerJanuary 1, 2022Pontecorvi G, Bellenghi M, Tait S, Tirelli V, Matarrese P, Mattia G, Carè A, Puglisi R.(Cell Signaling, #9665), PARP (Cell Signaling, #9532), Phalloidin (Alexa Fluor 488, #A12379), Wee1 (Santa Cruz, #5285), p-H2AX (Cell Signaling, #9718), TWIST (Abcam, clone 2C1a #ab50887), SLUG (Santa Cruz, sc-166476),

(6) Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathwaysImmunity, Inflammation and DiseaseDecember 1, 2021Chang Xu, Yilan Song, Zhiguang Wang, Jingzhi Jiang, Yihua Piao, Li Li, Shan Jin, Liangchang Li, Lianhua Zhu, Guanghai YansiAMPK (#6620; Cell Signaling Technology), siSirt1 (#12241; Cell Signaling Technology) and siNrf2 (#5285; Cell Signaling Technology) groups with Lipofectamine 2000 (#11668027; Invitrogen). After 6 h, fresh

(7) Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathwayBioscience reportsDecember 20, 2019Gu R, Huang Z, Liu H, Qing Q, Zhuan Z, Yang L, Su Z, Huang W.nucleus pulposus cells were plated on 6-well plates with 4 × 10 4 cells/ml in 1-ml culture medium. Nrf-2 siRNA (#5285, Cell Signaling Technology) (forward 5 -GGAGAGCCCAAUGUUUCAUTT-3 and reverse 5 -AUGAAACAUUGGGCUCUCCTT-3

(8) Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemiaNature communicationsFebruary 20, 2018Herling CD, Abedpour N, Weiss J, Schmitt A, Jachimowicz RD, Merkel O, Cartolano M, Oberbeck S, Mayer P, Berg V, et al.

(9) Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approachPloS oneJanuary 1, 2018de Jong MRW, Visser L, Huls G, Diepstra A, van Vugt M, Ammatuna E, van Rijn RS, Vellenga E, van den Berg A, Fehrmann RSN, et al.

(10) Troxerutin Reduces Kidney Damage against BDE-47-Induced Apoptosis via Inhibiting NOX2 Activity and Increasing Nrf2 ActivityOxidative Medicine and Cellular LongevityOctober 15, 2017Qun Shan, Juan Zhuang, Guihong Zheng, Zifeng Zhang, Yanqiu Zhang, Jun Lu, Yuanlin Zheng

(11) Prolonged mitotic arrest induced by Wee1 inhibition sensitizes breast cancer cells to paclitaxelOncotargetSeptember 26, 2017Lewis CW, Jin Z, Macdonald D, Wei W, Qian XJ, Choi WS, He R, Sun X, Chan G.

(12) Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in miceOncotargetJune 14, 2016Pei-Ling Hsu, Fan-E Mo

(13) MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genesOncotargetFebruary 23, 2016Soriano A, París-Coderch L, Jubierre L, Martínez A, Zhou X, Piskareva O, Bray I, Vidal I, Almazán-Moga A, Molist C, et al.

Be the First to Write a Review!