SignalSilence ® FoxO1 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® FoxO1 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6242S
Quantity300 µl
TargetFoxO1a
NCBI Gene AliasesFKH1, FKHR, FOXO1A
NCBI Full Gene Nameforkhead box O1
Research AreaPI3K / Akt Signaling
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial CellsInternational Journal of Molecular SciencesJanuary 24, 2024Daichi Ishii, Yuma Shindo, Wataru Arai, Takumi Konno, Takayuki Kohno, Kazuya Honda, Masahiro Miyajima, Atsushi Watanabe, Takashi Kojimasynthesized by Thermo Fisher Scientific (Waltham, MA, USA). An siRNA duplex oligonucleotide against FOXO1 (#6242) was obtained from Cell Signaling Technology (Danvers, MA, USA). The sequences were as follows: siRNA

(2) FOXO1 promotes the expression of canonical WNT target genes in examined basal-like breast and glioblastoma multiforme cancer cellsFEBS open bioNovember 1, 2023Pintor S, Lopez A, Flores D, Lozoya B, Soti B, Pokhrel R, Negrete J, Persans MW, Gilkerson R, Gunn B, et al.Invitrogen, Carlsbad, CA). We also utilized FOXO1 RNAi from Cell Signaling Technologies with control (cat: 6242, 6256, and 6568, respectively) and obtained the same results as the Sigma esiRNA. FOXO1 disruption The

(3) The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus ReplicationmBioAugust 30, 2022Hongbo Zhang, Anthony J. Domma, Felicia D. Goodrum, Nathaniel J. Moorman, Jeremy P. Kamil2 (catalog no. D-001206-14-05), SignalSilence FoxO1 siRNA I (Cell Signaling Technology; catalog no. 6242), and SignalSilence FoxO3a siRNA I (Cell Signaling Technology; catalog no. 6302). RNA was extracted

(4) Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4Redox biologyJune 1, 2022Ying KE, Feng W, Ying WZ, Li X, Xing D, Sun Y, Chen Y, Sanders PW.Duplex (Locus ID 847, OriGene Technologies Inc., Rockvile, MD), SignalSilence® FoxO1 siRNA I (Cat# 6242, Cell Signaling Technology, Danvers, MA), and SignalSilence® FoxO3a siRNA I (Cat# 6302, Cell Signaling Technology

(5) Trichostatin A activates FOXO1 and induces autophagy in osteosarcomaArchives of Medical ScienceJanuary 1, 2019Yunjuan Bai, Yun Chen, Xiaochen Chen, Jiukun Jiang, Xiao Wang, Liping Wang, Jigang Wang, Jianbin Zhang, Liang Gaotransient transfection The scrambled RNAi oligonucleotides and siRNA targeting FOXO1 (Cell Signaling Technology, 6242) were transfected into U2OS cells using the DharmaFECT 4 Transfection Reagent (Dharmacon, T-2001-02)

(6) Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancerTherapeutic Advances in Medical OncologyJuly 13, 2018Naomi Elster et al.Gene/mutation,Domain,AVSIFTvalue,Predicted effect(Mutation Assessor),COSMIC ID,Accession number EGFR V769L,Kinase,0.24,"T, PD",6242,P00533 EGFR A839T,Kinase,0,"D, PD",13430,P00533 EGFR K846R,Kinase,0.03,Borderline D/B,13431,P00533 HER2

(7) Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cellsMolecular Medicine ReportsJanuary 17, 2018Liang Gao, Xin Sun, Qi Zhang, Xiaochen Chen, Tongwei Zhao, Liqing Lu, Jianbin Zhang, Yupeng HongLafayette, CO, USA) was used to transfected the scramble RNAi oligonucleotides and siRNAs targeting FOXO1 (6242; Cell Signaling Technology, Inc.) into MCF10A-ras cells according to manufacturer's instructions. After

(8) Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin BRedox biologyAugust 1, 2017Xu J, Wu Y, Lu G, Xie S, Ma Z, Chen Z, Shen HM, Xia D.GAUCUAAAUCUCAAACUGA; GCCCACAGAUGGAGUAGCA; GCCAGAGGAUUCAACAUGA) and scramble siRNA (Cell Signaling Technology, 6242) were transfected into HCT116 cells by Lipofectamine 3000 (Life Technologies, L3000015) according to

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