SignalSilence ® Stat3 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® Stat3 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6580S
Quantity300 µl
TargetSTAT3
NCBI Gene AliasesADMIO, ADMIO1, APRF, HIES
NCBI Full Gene Namesignal transducer and activator of transcription 3
Research AreaMAP Kinase Signaling
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cellsScientific ReportsDecember 1, 2021Xiang Chen et al.siRNA transfection and viability assay SignalSilence STAT3 siRNA I was purchased from Cell Signaling (#6580) and medulloblastoma cells were transfected using Lipofectamine 2000 reagent (Invitrogen). The sequence

(2) Lamin A/C Is Dispensable to Mechanical Repression of AdipogenesisInternational journal of molecular sciencesJune 19, 2021Goelzer M, Dudakovic A, Olcum M, Sen B, Ozcivici E, Rubin J, van Wijnen AJ, Uzer G.washed and incubated with horseradish-peroxidase-conjugated secondary Int. J. Mol. Sci. 2021, 22, 6580 17 of 20 antibody diluted at 1:5000 (Cell Signaling Technology) at RT for 1 h in 5% milk in TBST-T. Chemiluminescence

(3) Mitochondrial Hyperactivation and Enhanced ROS Production are Involved in Toxicity Induced by Oncogenic Kinases Over-SignalingCancers (Basel)December 12, 2018Monica Ceccon, Mario Mauri, Luca Massimino, Giovanni Giudici, Rocco Piazza, Carlo Gambacorti-Passerini, Luca Molognisilencing, specific siRNAs were purchased from Cell Signaling Technology—Danvers, MA, USA (#6275 and #6580) and used at 50 nM concentration in medium alone and 20 µL of INTERFERIN (Polyplus transfection, -Bioparc—850,

(4) Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of MacrophagesPloS oneJanuary 1, 2016Deiuliis JA, Syed R, Duggineni D, Rutsky J, Rengasamy P, Zhang J, Huang K, Needleman B, Mikami D, Perry K, et al.

(5) Mycoplasma pneumoniae modulates STAT3-STAT6/EGFR-FOXA2 signaling to induce overexpression of airway mucinsInfection and immunityDecember 1, 2014Hao Y, Kuang Z, Jing J, Miao J, Mei LY, Lee RJ, Kim S, Choe S, Krause DC, Lau GW.cells was determined with the anti-FOXA2 antibody. siRNA studies. siRNAs against EGFR (6480S), STAT3 (6580S), and STAT6 (6358S) and the random, nontargeting siRNA sequence (SignalSilence Control siRNA, unconjugated,

(6) Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B Leukemic CellsBMC CancerDecember 1, 2011Ganchimeg Ishdorj, James B Johnston, Spencer B Gibsonand total Erk1/2, XIAP and STAT3 antibodies, as well as siRNA for c-Jun (#6203) and Stat3 siRNA I (#6580) and control siRNA (#6201 fluorescein conjugate) were purchased from Cell Signaling Technology, VEGF

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