SignalSilence ® beta-Catenin siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® beta-Catenin siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6225S
Quantity300 µl
TargetCatenin-beta
NCBI Full Gene Namecatenin beta 1
NCBI Gene AliasesCTNNB, EVR7, MRD19, NEDSDV, armadillo
Research AreaDevelopmental Biology
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivobioRxivApril 11, 2026Tianzheng Ye, Azmain Alamgir, Cara M. Robertus, Darianna Colina, Connor Monticello, Thomas Connor Donahue, Lauren Hong, Sophia Vincoff, Shrey Goel, Peter Fekkes, et al.analysis. For siRNA transfection, a final concentration of 100 nM CTNNB1 siRNA (Cell Signaling, cat # 6225) was transfected in each well of a 96-well plate (100 μl per well) using jetPRIME reagent. Immunoblot

(2) FH535-mediated inhibition of Wnt/β-catenin suppresses CRC growth and invasion and alters MCP1 and MCP2 expression with potential immunological implicationsFront OncolApril 1, 2026Aisha Saleh Janeeh, Bilal Rah, Jasmin Shafarin, Khuloud Bajbouj, Eman Abu-Gharbieh, Mawieh Hamadfrom ThermoFisher Scientific and SignalSilenceR β-catenin siRNA (targeting Homo sapiens β-catenin; 6225S) were procured from Cell Signaling Technology. Briefly, CRC (HCT116 and HT29) cells were seeded in 6-well

(3) Regulation of E-cadherin by mixed lineage kinase 3 (MLK3) mediates cell adhesion in ovarian cancer spheroidsBiochimica et Biophysica Acta (BBA) - Molecular Cell ResearchMarch 1, 2026Mariah C.J. Rozier, Danielle N. Adjei, Rachel A. Radtke, Deborah N. Chadee(Lafayette, CO, USA) and target sequences are as previously described [40]. β-catenin siRNA oligo 1 (6225) and 2 (6238) were from Cell Signaling Technology (Danvers, MA, USA). Cells were transfected with 150

(4) Increasing expression of presenilin 1, β-catenin, and p-PTEN and its regulatory roles on cell invasion in gastric cancerWorld J Gastrointest OncolFebruary 15, 2026Xi Lin, Guo-Feng Lin, Fei-Teng Gu, Yong-Liang Liplasmid (HanbioTM, Shanghai, China) for lentiviral production. β-catenin small interfering RNA (siRNA) (#6225) and control siRNA (#6568) were purchased from Cell Signaling Technology, MA, United States. Stable

(5) β-Catenin-NF-κB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reactioneLifeOctober 5, 2021Hu S, Russell JO, Liu S, Cao C, McGaughey J, Rai R, Kosar K, Tao J, Hurley E, Poddar M, et al.(Invitrogen, L3000008), or together with si-Control (Cell Signaling, 6568) and si-β-catenin (Cell Signaling, 6225) to knock down β-catenin using Lipofectamine RNAiMAX Transfection Reagent (Invitrogen, 13778150). For

(6) HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1CancersSeptember 26, 2019Beyer M, Romanski A, Mustafa AM, Pons M, Büchler I, Vogel A, Pautz A, Sellmer A, Schneider G, Bug G, et al.at the following concentrations: β-catenin (100 pmol; Cell Signaling Technology, Frankfurt, Germany, #6225), MYC (100 pmol; Santa Cruz, Heidelberg, Germany, sc-29226), and WT1 (100 pmol; Santa Cruz, Heidelberg,

(7) Fibroblast-Specific β-Catenin Signaling Dictates the Outcome of AKIJournal of the American Society of Nephrology : JASNApril 1, 2018Zhou D, Fu H, Xiao L, Mo H, Zhuo H, Tian X, Lin L, Xing J, Liu Y.indicated. NRK-49F cells were also transiently transfected with control siRNA or b-catenin–speciﬁc siRNA (#6225; Cell Signaling Technology, Danvers, MA) by using Lipofectamine 2000 reagent (Invitrogen, Grand Island,

(8) Astragalus Inhibits Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells by Down-Regulating β-CateninCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Yu M, Shi J, Sheng M, Gao K, Zhang L, Liu L, Zhu Y.anti-phospho-GSK3β (Ser9), anti-β-actin, anti-GAPDH, anti-Histone H3 antibodies, SignalSilence β-catenin siRNAs (#6225, #6238), and secondary horseradish peroxidase (HRP)-conjugated goat anti-rabbit and anti-mouse IgG were obtained

(9) Elevated PTH induces endothelial-to-chondrogenic transition in aortic endothelial cellsAmerican journal of physiology. Renal physiologyMarch 1, 2017Wu M, Zhang JD, Tang RN, Crowley SD, Liu H, Lv LL, Ma KL, Liu BC.for 7 days. siRNA transfection. The ␤-catenin siRNA was purchased from Cell Signaling Technology (no. 6225). The nontargeting scramble-sequence siRNA was used as a negative control. The siRNA transfection study

(10) p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingNature communicationsJune 27, 2016Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, et al.

(11) TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasionCell death & diseaseOctober 2, 2014Joseph JV, Conroy S, Tomar T, Eggens-Meijer E, Bhat K, Copray S, Walenkamp AM, Boddeke E, Balasubramanyian V, Wagemakers M, et al.Stealth RNAi (OriGene SR304746, Rockville, MD, USA) specific to ZEB1 and β-Catenin (Cell Signaling # 6225) was transfected into U87 cells by using Lipofectamine RNAiMAX (Thermo Fisher Scientific) according

(12) MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1ROncotargetAugust 15, 2014Ge YY, Shi Q, Zheng ZY, Gong J, Zeng C, Yang J, Zhuang SM.overnight, followed by staining with the Alexa488-labeled goat antiwww.impactjournals.com/oncotarget 6225 Oncotarget Analysis of mitochondrial membrane potential (ΔΨm) a circular region around the xenograft

(13) Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradationJournal of experimental & clinical cancer research : CRJanuary 1, 0001"Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, Li L, Lin D, Luo X, Xu J, et al."

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SignalSilence ® β-Catenin siRNA I

SignalSilence ® beta-Catenin siRNA I from Cell Signaling Technology

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Cell Signaling Technology

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SignalSilence ® beta-Catenin siRNA I from Cell Signaling Technology

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