m7G(5)ppp(5)A RNA Cap Structure Analog from New England Biolabs

Product Specs
Itemm7G(5)ppp(5)A RNA Cap Structure Analog
CompanyNew England Biolabs
Price $174.00 Inquire
Catalog NumberS1405S
Quantity1 µmol
ApplicationsFunctional Genomics
Temperature-20 C

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New England Biolabs

240 County Road

Ipswich, Massachusetts 1938

United States

Phone: 800-632-5227
800-632-7799
978-921-1350

Company Profile

Website: http://www.neb.com

(1) Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic lifeCellFebruary 17, 2026J. Maximilian Fels, Aidan B. Hill, Richard Han, Jasmine M. Garcia, Hugo Bisio, Chantal Abergel, Philip J. Kranzusch, Amy S.Y. Lee,Sigma Aldrich,Cat#M6133 m7G(5’)ppp(5’)G RNA Cap Structure Analog,NEB,Cat#S1404S m7G(5’)ppp(5’)A RNA Cap Structure Analog,NEB,Cat#S1405S m7GP3C,Jena Biosciences,Cat#NU-512S GTP,NEB,Cat#N0450L PEI 40K,Polysciences,Cat#24765 Geneticin/G-418,Gibco,Cat#10131035 ,, Critical

(2) Replicon-based genome-wide CRISPR knockout screening for the identification of host factors involved in viral replicationNat CommunDecember 10, 2025Karen W. Cheng, Madhura Bhave, Andrew L. Markhard, Duo Peng, Karan D. Bhatt, Katherine A. Travisano, Josette V. Medicielo, Astrid Anaya, Sanae Lembirik, Leila Njoya, et al.MEGAscript T7 Transcription Kit (Ambion, AM1334) with the addition of 4 mM of m7G(5′)ppp(5′)G cap analog (NEB, S1405S) per reaction. The reaction was incubated for 4 h at 33 °C, followed by addition of 1 µL of Turbo DNAse

(3) DDX6 interacts with DDX3X to repress translation in microRNA-mediated silencingNucleic Acids ResearchSeptember 9, 2025Yanyan Lu, Meng Tao, Hong Su, Yiren Tu, Ji-Ping Wang, Masahiko Kuroda, Xiaozhong WangMAXIscript T7 Transcription Kit (Thermo Fisher Scientific, AM1314M) in the presence of m7GpppG cap analog (NEB, S1405S). mRNA products were treated with DNase I to remove DNA templates and purified with RNA Clean & ConcentratorTM-5

(4) A Japanese encephalitis virus biological clone with an E gene point mutation exhibits in vitro and in vivo attenuation of neurovirulenceJournal of General VirologySeptember 1, 2025Shu Pin Yu, Kien Chai Ong, Soon Hao Tan, Tomohiro Ishikawa, David Perera, Yuan Teng Hooi, Kum Thong WongMEGAscript T7 Transcription kit (Ambion, Thermo Fisher Scientific, USA) with the 5′ cap analogue m7G(5′)ppp(5′)A (S1405S) (New England Biolabs, Ipswich, USA). The in vitro-transcribed RNAs were treated with TURBO DNase1 at

(5) The mechanism of RNA capping by SARS-CoV-2NatureSeptember 22, 2022Gina J. Park et al.RNA cap structure analogue (GpppA; S1406L) and m7G(5′)ppp(5′)A RNA cap structure analogue (m7GpppA; S1405S) were all obtained from New England Biolabs. Acetic acid (A38-212), RNase inhibitor (N8080119), 2× TBE-urea

(6) The mechanism of RNA capping by SARS-CoV-2Research SquareSeptember 16, 2022Vincent Tagliabracci et al.G(5′)ppp(5′)A RNA Cap Structure Analog (GpppA; S1406L), and m7G(5′)ppp(5′)A RNA Cap Structure Analog (m7GpppA; S1405S) were all obtained from New England Biolabs (Ipswich, MA). Acetic acid (A38-212), RNAse inhibitor (N8080119),

(7) Splice site m⁶A methylation prevents binding of U2AF35 to inhibit RNA splicingCellJune 10, 2021Mendel M, Delaney K, Pandey RR, Chen KM, Wenda JM, Vågbø CB, Steiner FA, Homolka D, Pillai RS.L8912-25G L-Cysteine,Sigma,Cat. no. C7602-25G m7G(5′)ppp(5′)A RNA Cap Structure Analog,NEB,Cat. no. S1405S "Pierce Protease Inhibitor Tablets, EDTA-free",Thermo Fisher,Cat. no. A32965 Benzonase Nuclease,Santa Cruz Biotechnology

(8) A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19SLAS DiscoveryJune 1, 2021Sumera Perveen, Aliakbar Khalili Yazdi, Kanchan Devkota, Fengling Li, Pegah Ghiabi, Taraneh Hajian, Peter Loppnau, Albina Bolotokova, Masoud Vedadi(Levisville, TX). The unlabeled Cap RNA, m7G(5′)ppp(5′G (NEB, cat. S1404S) and m7G(5′)ppp(5′)A (NEB, cat. S1405S), also referred to as N7-meGpppG and N7-meGpppA for consistency, respectively; G(5′)ppp(5′)A RNA (GpppA)

(9) An RNA-centric dissection of host complexes controlling flavivirus infectionNature microbiologyDecember 1, 2019Ooi YS, Majzoub K, Flynn RA, Mata MA, Diep J, Li JK, van Buuren N, Rumachik N, Johnson AG, Puschnik AS, et al.Kit (Ambion AM1334) with the reaction containing 5mM m7G(5’)ppp(5’)G RNA Cap Structure Analog (NEB S1405S). Resulting RNA was purified by sodium acetate ethanol precipitation. HEK293FT cells were washed twice

(10) Capturing the Mechanism Underlying TOP mRNA Binding to LARP1StructureDecember 1, 2019Kevin C. Cassidy, Roni M. Lahr, Jesse C. Kaminsky, Stephanie Mack, Bruno D. Fonseca, Subha R. Das, Andrea J. Berman, Jacob D. Durrantmutant was concentrated to ~10 mg/mL in 25 mM Hepes, pH 7.0, and 75 mM NaCl. FYRE and m7GpppG (NEB cat#S1405S) were incubated at a 1:1.2 ratio at room temperature (final concentrations of 480 μM (9 mg/mL) DM15

(11) Random Insertional Mutagenesis of a Serotype 2 Dengue Virus CloneBIO-PROTOCOLAugust 20, 2018Jeffrey W. Perry, Andrew W. Taicatalog number: A9281) m7g(5’)ppp(5’)A RNA Cap Structure analog (New England Biolabs, catalog number: S1405S) Agarose (Thermo Fisher Scientific, catalog number: 16500100) Q5 polymerase (New England Biolabs,

(12) Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screensNatureJuly 7, 2016Marceau CD, Puschnik AS, Majzoub K, Ooi YS, Brewer SM, Fuchs G, Swaminathan K, Mata MA, Elias JE, Sarnow P, et al.Kit (Ambion AM1334) with the reaction containing 5mM m7G(5′)ppp(5′)G RNA Cap Structure Analog (NEB S1405S). Resulting RNA was purified by sodium acetate ethanol precipitation. HCV sgJFH1 replicon33 RNA was

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