C6 from ATCC

Product Specs
ItemC6
CompanyATCC
Price $264.00Supplier Page View Company Product Page
Catalog NumberCCL-107
SpeciesRattus norvegicus
TypeCell Biology
Cell Typeglial cell
Validated Species ReactivityRat (Rt)
DiseaseGlioma
TissueBrain
ApplicationsThis cell line is a suitable transfection host

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Assessing progesterone receptor modulation in glioblastoma: from in vitro and animal model to a human pilot protocolCancer Biol TherDecember 31, 2026Denisse Arcos-Montoya, Patricia García-López, Talia Wegman-Ostrosky, Ignacio Camacho-Arroyo, Silvia Anahí Valdés-Rives, Claudia Bello-Alvarez, Joaquín Manjarrez-Marmolejo, Marisol De La Fuente-Granada, Alejandro Ordaz-Ramos, Daniela Ávila-González, et al.Nacional de Medicina Genómica by PCR, LDG-INMEGEN: 00451, LDG: 451-2), and murine glioma cell line C6 (CCL-107™ Lot: 58078536, ATCC®, USA, Appendix C) were cultured in DMEM medium with 10% FBS. T47D and HCC70 breast cancer

(2) Protocol for quantifying miRNA trafficking across the endosomal membraneFEBS Open BioJuly 26, 2026Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyyaphosphate‐buffered saline (PBS) (pH = 7.4); Gibco (Cat no.: 10010‐023).C6 (Rat Glial cell line); ATCC (Cat no.: CCL‐107).HEK‐293; ATCC (Cat no.: CRL‐1573).Microprocessor‐controlled air system class II biohazard safety cabinet;

(3) miR-132 overexpression is associated with modulation in miR-21 expression and glioblastoma cell behaviorPLoS OneJuly 10, 2026Kimia Abdi, Hadi Bayat, Seyed Javad Mowlaelectroporation Human GBM cell line U87 (ATCC Cat# HTB-14, RRID: CVCL_0022) and rat glioma cell line C6 (ATCC Cat# CCL-107, RRID: CVCL_0194) were cultured in DMEM/F12 medium (Gibco, Cat# 12500096) supplemented with 10% fetal

(4) The amino acid substitutions A30W, K28A, and M35C alter amyloid-β peptide toxicity in cell culture and in an in vivo model of amyloidosis in Caenorhabditis elegansFrontiers in Aging NeuroscienceJune 29, 2026Diana Patricia Quijano-Guerrero, Ana Esther Estrada-Rodríguez, Mauricio Caballero-Rodríguez, Danna Loretta de León-Rivera, Cristina Rodríguez-Padilla, Victor Julian Valdes, Diana Caballero-Hernández, Román Vidaltamayo, Ana Carolina Martínez-Torres, Viviana Zomosa-Signoretand incubated for 96 h at 37°C and 340 rpm before assays. 2.2 Cell culture C6 rat glioma cell line (CCL-107, ATCC, Manassas, VA., United States) was cultured in Dulbecco’s Modified Eagle Medium (Caisson, North

(5) Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signalingbioRxivMarch 23, 2026Jennifer J. Tuscher, Angela Cleere, Robert A. Phillips, Catherine E. Newman, Guy Twa, Nathaniel J. Robinson, Lara Ianov, Robert E. Sorge, Jeremy J. Dayfor in vitro rat glia experiments were acquired from American Type Culture Collection (ATCC; cat # CCL-107) and maintained in Ham’s F12k-based medium (Thermo Fisher Scientific, cat # 21127022) supplemented with

(6) Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastomaFrontiers in OncologyMarch 4, 2026John McDaid, Julian E. Bailes, Neilank K. Jha, George Bobustuc, Reed Berlet, Cassidy Kessinger, Eliana Whitcomb, John M. Lee, Daniil P. Aksenov, Matthew Walker, et al.complete. 2.3 C6 glioma cell culture Rat C6 Glioma cells (American Type Culture Collection (ATCC), Cat. No. CCL-107) were cultured in FK-12 medium supplemented with penicillin/streptomycin (1%) and fetal bovine serum

(7) A Ru(ii)-arene complex with promising anti-Aβ activityRSC AdvFebruary 2, 2026Ryan M. Hacker, Jacob J. Smith, David C. Platt, Maria I. Loughlin, Emma N. Grabowski, William W. Brennessel, Marjorie A. Jones, Michael I. WebbRattus norvegicus pheochromocytoma cells (PC-12; ATCC CRL-1721) and axenic Rattus norvegicus C6 glioma cells (ATTC CCL-107) following previous procedures.15 Results and discussion Synthesis and characterization All of the

(8) Theranostic Angiopep-2-Conjugated FeTaO x @Au Core–Shell Magnetic Nanoparticles for Glioma Treatment and Dual Medical ImagingACS Applied Bio MaterialsJanuary 19, 2026Kayalvizhi Samuvel Muthiah, Senthilkumar Thirumurugan, Susaritha Ramanathan, Ming-Hsuan Yeh, Udesh Dhawan, Yu-Chien Lin, Ching-Po Lin, Wai-Ching Liu, Yuan-Yun Tseng, Ching-Li Tseng, et al.increased, suggesting that the effect was concentration-dependent. 2.10 Cell Culture C6 rat glioma cells (CCL107; ATCC) and L929 mouse fibroblasts (CCL1; ATCC) were grown in Dulbecco’s modified Eagle’s medium (DMEM)

(9) A triple-action PROTAC for wild-type p53 cancer therapyCell Reports MedicineDecember 16, 2025Gregory H. Bird, Utsarga Adhikary, Michael J. Schmidt, Marina Godes, Bethany Tesar, Christina M. Camara, Joao A. Paulo, Julia F. Vidlak, Thomas M. DeAngelo, Marilyn Marquez, et al.Laboratory,N/A HCT116 WT,ATCC,Cat# CCL-247 HCT116 p53−/−,B. Vogelstein Laboratory,N/A C6,ATCC,Cat# CCL-107 DI-TNC1,ATCC,Cat# CRL-2005 ,, Experimental models: Organisms/strains,Experimental models: Organisms/strains,Experimental models

(10) An implantable, intracerebral osmotic pump for convection-enhanced drug delivery in glioblastoma multiformeFront OncolOctober 8, 2025Reed Berlet, Azur Azapagic, Neilank K. Jha, Daniil Aksenov, Jade Bookwalter, Ata Ullah, George Bobustuc, John Lee, Himanshu Sant, John McDaid, et al.were used for this study. 2.3.2 C6 glioma cell cultures Vials containing frozen C6 glioma cells (CCL-107, ATCC) were thawed rapidly with gentle agitation in a 37 °C water bath. Cells were then transferred

(11) Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoAElifeJuly 23, 2025Aurelie Carabalona, Henna Kallo, Maryanne Gonzalez, Liliia Andriichuk, Ellinoora Elomaa, Florence Molinari, Christiana Fragkou, Pekka Lappalainen, Marja W Wessels, Juha Saarikangas, et al.and transfection We used the C6 rat glioma cell line in this study. The cells were obtained from ATCC (Cat# CCL-107). Cell line identity was authenticated by short tandem repeat profiling. Mycoplasma contamination was

(12) Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoAElifeJuly 23, 2025Aurelie Carabalona, Henna Kallo, Maryanne Gonzalez, Liliia Andriichuk, Ellinoora Elomaa, Florence Molinari, Christiana Fragkou, Pekka Lappalainen, Marja W Wessels, Juha Saarikangas, et al.and transfection We used the C6 rat glioma cell line in this study. The cells were obtained from ATCC (Cat# CCL-107). Cell line identity was authenticated by short tandem repeat profiling. Mycoplasma contamination was

(13) Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expressionFEBS Open BioMay 5, 2025María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mataglioblastoma cell line U‐138 (ATCC; cat. no.: HTB‐16) and the rat glioma C6 cell line (ATCC; cat. no.: CCL‐107) were from American Type Culture Collection (ATCC, Manassas, VA, USA). IL‐1α and TNF‐α were supplied

(14) Ruthenium(II)–Arene Complexes with a 2,2′-Bipyridine Ligand as Anti-Aβ AgentsBiomoleculesMarch 25, 2025Ryan M. Hacker, Jacob J. Smith, David C. Platt, William W. Brennessel, Marjorie A. Jones, Michael I. WebbRattus norvegicus pheochromocytoma cells (PC-12; ATCC CRL-1721) and axenic Rattus norvegicus C6 glioma cells (ATTC CCL-107) were prepared as previously reported [28]. The cells were cultured using Dulbecco’s Modified Eagle’s

(15) Efficient Production of Recombinant Human Brain-Derived Neurotrophic Factor in Escherichia coli Through the Engineering of Its Pro-RegionInternational Journal of Molecular SciencesDecember 14, 2024Elisa Spaccapaniccia, Tiziano Cazzorla, Daniela Rossetti, Lucio De Simone, Maria Irene Antonangeli, Andrea Antonosante, Francesca Galli, Franca Cattani, Mariano Maffei, Franck Martinversion 1.7.2). 4.14. C6 Proliferation Assay Rat glioma C6 cells were purchased from ATCC (catalogue # CCL-107) and cultured in DMEM medium (Gibco, Texas, TX, USA, code # 11960-044) supplemented with 10% fetal bovine

(16) γ-Glutamyl transpeptidase-activable nanoprobe crosses the blood-brain barrier for immuno-sonodynamic therapy of gliomaNature CommunicationsNovember 29, 2024Bo Li, Gengjia Chen, Huihai Zhong, Tan Li, Minzhao Lin, Huiye Wei, Qiaoyun Zhang, Qi Chen, Jinsheng Huang, Xintao Shuairegression analysis method. Cell culture The mice glioma cells (G422), rat glioma cells (C6, Catalog No. CCL-107 (ATCC)), human glioma cells (U87, Catalog No. HTB-14 (ATCC)), and luciferase protein gene recombinant

(17) Eslicarbazepine induces apoptosis and cell cycle arrest in C6 glioma cells in vitro and suppresses tumor growth in an intracranial rat modelBMC CancerSeptember 4, 2024Nastaran Afsordeh, Safura Pournajaf, Hadi Bayat, Fatemeh Mohajerani, Amir Shojaei, Javad Mirnajafi-Zadeh, Mohammad Hossein Pourgholamiin male rats bearing C6 intracranial tumors. Materials and methods Cell line C6 cells (ATCC Cat# CCL-107, RRID: CVCL_0194) were cultured in DMEM/F12 (GIBCO; Cat. #12500096) medium supplemented with 10% fetal

(18) TiO2-ZnPc nanoparticles functionalized with folic acid as a target photosensitizer for photodynamic therapy against glioblastoma cellsJournal of Materials Science: Materials in MedicineAugust 22, 2024Gustavo Jardón-Guadarrama, Ma Elena Manríquez-Ramírez, Citlali E. Rodríguez-Pérez, Araceli Díaz-Ruiz, María de los Ángeles Martínez-Cárdenas, Alfonso Mata-Bermudez, Camilo Ríos, Emma Ortiz-Islashand, the chemical and biological substances used in this work are listed below: C6 glial cell line (CCL-107, ATCC), fetal bovine serum (Biowest), Dulbecco’s Modified Eagle’s (DMEM), trypsin-EDTA, penicillin and

(19) Fatty Acid Amides Suppress Proliferation via Cannabinoid Receptors and Promote the Apoptosis of C6 Glioma Cells in Association with Akt Signaling Pathway InhibitionPharmaceuticals (Basel)July 2, 2024Nágila Monteiro da da Silva, Izabella Carla Silva Lopes, Adan Jesus Galué-Parra, Irlon Maciel Ferreira, Chubert Bernardo Castro de de Sena, Edilene Oliveira da da Silva, Barbarella de Matos Macchi, Fábio Rodrigues de de Oliveira, José Luiz Martins do Nascimentoamides in vivo animal studies. 4. Materials and Methods 4.1. Cell Culture The C6 glioma cell line (CCL-107™, ATCC) used in this study was maintained in Dulbecco’s Modified Eagle’s Medium (DMEM), supplemented

(20) The thrombin receptor (PAR1) is associated with microtubules, mitosis and process formation in glioma cells☆HeliyonJune 30, 2024Valery Golderman, Shany Guly Gofrit, Yanina Ivashko-Pachima, Illana Gozes, Joab Chapman, Efrat Shavit-Steindoes not report original code. 9 Experimental model and subject details 9.1 Cells Rat glioma C6 (CCL-107. ATCC) cells were purchased from ATCC company. The cells were evaluated for mycoplasma contamination,

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C6 from ATCC

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