AT3B-1 from ATCC

Product Specs
ItemAT3B-1
CompanyATCC
Price $0.00Supplier Page View Company Product Page
Catalog NumberCRL-2375
SpeciesRattus norvegicus
TypeCell Biology
Validated Species ReactivityRat (Rt)
Age22 months
DiseaseCarcinoma
TissueProstate
ApplicationsAT3B-1 was derived from the AT-3 cell line.They are more resistant to vinblastine compared to controls.These cells express a multidrug (MDR) resistant phenotype.Injection of AT3 B-1 cells into rats followed by doxorubicin treatment produced larger tumors compared to the parental controls.When P-glycoprotein was blocked, the AT3 B-1 cell line demonstrated drug efflux pump activity.This cell line can be used to study chemotherapy resistance in prostate cancer

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Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Acquired Drug Resistance Enhances Imidazoquinoline Efflux by P-GlycoproteinPharmaceuticals (Basel, Switzerland)December 10, 2021Pulukuri AJ, Burt AJ, Opp LK, McDowell CM, Davaritouchaee M, Nielsen AE, Mancini RJ.[53]. The AT3B-1 cell line was purchased from ATCC. The AT3B-1 cell line (ATCC, Manassas, VA, USA, CRL-2375, rat MDR prostate carcinoma) was grown in complete culture media composed of DMEM with 4.5 g L−1 glucose,

(2) Immune responses against PSMA after gene-based vaccination for immunotherapy – A: results from immunizations in animalsCancer Gene TherapyApril 1, 2006M Mincheff, S Zoubak, Y Makogonenkovector containing zeocin resistance gene. AT3B-1 transfection with hPSMAs Monolayers of AT3B-1 cells (CRL-2375; ATCC, Manassas, VA) were transfected with the hPSMAs using the FuGENE6 transfection reagent (Roche

(3) Depletion of CD25+ cells from human T-cell enriched fraction eliminates immunodominance during priming with dendritic cells genetically modified to express a secreted proteinCancer gene therapyFebruary 1, 2005Mincheff M, Zoubak S, Altankova I, Tchakarov S, Pogribnyy P, Makogonenko Y, Botev C, Meryman HT.Woodlands, TX). The human LNCaP (CRL-1740), T2 (CRL-1992), Malme 3 M (HTB-64), COS-1 (CRL-1650) and AT3B-1 (CRL2375) cell lines were purchased from ATCC and were maintained according to ATCC instructions. Cytokines

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AT3B-1 from ATCC

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