Puromycin dihydrochloride from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPuromycin dihydrochloride
CompanySanta Cruz Biotechnology, Inc.
Price $40.00Supplier Page View Company Product Page
Catalog Numbersc-108071
Quantity25 mg
TypeBiochemical Reagents
Molecular Weight544.43

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Loss of Peroxiredoxin 6 Drives Age-Related Klf9/NF-κB/Nlrp3 Inflammasome Activation and Pyroptosis: Therapeutic Rescue by Prdx6Antioxidants (Basel)April 23, 2026Bhavana Chhunchha, Eri Kubo, Deepali Lehri, Dhirendra P. Singhwere added. Infected SRA-hLECs and mLECs were subcultured and treated with puromycin dihydrochloride (sc-108071, Santa Cruz Biotechnology) to select for stable integrants. Puromycin-resistant cells were maintained

(2) SPNS2 exports sphingosine-1-phosphate and imports glucoseNat CommunApril 20, 2026Cynthia Weigel, Md Lokman Hossen, Ryan D. R. Brown, Can E. Senkal, Christopher D. Green, Jason Newton, Sumit Saha, Elisa N. D. Palladino, Bin Ni, Francesco S. Celi, et al.containing 2 µg/mL puromycin dihydrochloride, 300 µg/mL hygromycin B and 5 µg/mL blasticidin-S-HCl (#sc-108071, #sc-29067, #sc-495389, Santa Cruz Biotechnology). For the transduction of lentiviral particles, cells

(3) Impact of SETD8/KMT5A overexpression on hepatocellular carcinoma progression and prognosisPLoS OneApril 13, 2026Norihiko Suzaki, Shinya Hayami, Atsushi Miyamoto, Masashi Nakamura, Tomohiro Yoshimura, Kensuke Nakamura, Yoshinobu Shigekawa, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi, et al.the recommended protocol (plasmid DNA final concentration: 1 µg/ml). Subsequently, 1 µg/ml puromycin (sc-108071, Santa Cruz Biotechnology) was added to the cell lines that underwent transfection treatment, and they

(4) Serglycin Cooperates with the Unfolded Protein Response Pathway and Inflammation to Drive Glioblastoma Cell SurvivalCellsApril 9, 2026Eleftherios N. Athanasopoulos, Chrysostomi Gialeli, Angeliki Natsiou, Dimitra Manou, Vassiliki T. Labropoulou, Achilleas D. Theocharisprotocol, as described previously [20]. Puromycin dihydrochloride, at the optimal concentration 0.8 μg/mL (sc-108071, Santa Cruz Biotechnology, Inc., Heidelberg, Germany) was used for the selection and manufacture of

(5) High-linear energy transfer radiation disrupts natural killer cell surveillance of senescent intestinal cells in the mouse intestineMol BiomedApril 7, 2026Santosh Kumar, Shubhankar Suman, Heng-Hong Li, Jerry Angdisen, Kamal Datta, Albert J. Fornacenew medium, and antibiotic selection was initiated after 48 h using puromycin (1.0 µg/mL; Santa Cruz, sc-108071) or neomycin (400 µg/mL; Santa Cruz, sc-255391). Following 5 days of selection, cells were returned

(6) Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid LeukemiaCancer ResApril 2, 2026Johanna Eriksson, Shuyu Zheng, Mihaela Popa, Jie Bao, Jun Dai, Wenyu Wang, Emmet McCormack, Anna Vähärautio, Jing Tangconditions o/n, after which cells were washed and grown for 3 days before adding 0.5 ug/ml puromycin (#sc-108071, Santa Cruz Biotechnology, Dallas, TX, USA) for 9 days to remove cells without barcodes. Barcoded cells

(7) Cystinosin regulates Na+/H+ exchanger 3 trafficking and function in kidney proximal tubular cellsEMBO ReportsMarch 24, 2026Veenita Khare, Jean-Claude Farré, Mouad Ait Kbaich, Céline J Rocca, Cynthia Tang, Xuan Ma, Kavya Biederman, Ioli Mathur, Rafael A Badell-Grau, Anusha Sivakumar, et al.albumin,Invitrogen,A34786 AnnexinV,Invitrogen,331200 7-amino-actinomycin D (7-AAD),Invitrogen,00-6993-50 Puromycin dihydrochloride,Santa cruz,sc-108071 Kidney FFPE tissue (non-cystinosis healthy donor),Zyagen,HP-901 Miltenyi LS columns,Miltenyi Biotec,130-042-401 Anti-Sca-1

(8) WNT7B drives a program for pancreatic cancer subtype switching and progressioniScienceMarch 20, 2026Joep Sprangers, Jeroen M. Bugter, Despina Xanthakis, Michiel Boekhout, Rutger N.U. Kok, Veerle E. Geurts, Hans Clevers, Lodewijk A.A. Brosens, Frederike Dijk, Maria J. Rodríguez Colman, et al.inhibitor),Tocris,2939/10 Polybrene (hexadimethrine bromide),Merck,3701-03-3 Puromycin,Santa Cruz,SC-108071 Matrigel,Corning,356231 Basement Membrane Extract (BME),R&D Systems,3533-010-02 (RGF) TrypLE,Thermo

(9) Nisin bacteriocin blocks T. denticola-triggered MMP2 activation and pathogen internalization via TLR2Scientific ReportsMarch 11, 2026Pachiyappan Kamarajan, Allan Radaic, Hossein Beheshti, Mishri Parikh, Sarah Lo, J Christopher Fenno, Yvonne L. Hernandez Kapilalentiviral particles in 0.5 mL of serum-free media containing polybrene then selected in 5 µg/mL puromycin (sc-108071; Santa Cruz Biotechnology) for an additional 10 days32. Surviving cell colonies were picked and propagated

(10) Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineageNat CommunMarch 9, 2026Irina Poverennaya, Aliia Murtazina, Lei Li, Lorena Maili, Lukas Sourada, Luis Fernando Montano-Gutierrez, Rozalina Galimullina, Tobias Steinschaden, Marketa Kaiser, Tomas Zikmund, et al.Stable transduced cell pools were selected by two rounds of 5-day treatment with 2 µg/ml puromycin (#sc−108071, Santa Cruz Biotechnology). RNA extraction, reverse transcription and qPCR were performed as previously

(11) DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsisNature CommunicationsMarch 9, 2026Wenchen Luo, Wei Xu, Qimeng Yin, Jieqiong Song, Jie Wang, Yian Guan, Jian Huang, Jian Yu, Kefeng Zou, Danfeng Jin, et al.Laboratories) for 24 h. At 48 h post-infection, RAW264.7 cells or BMDMs were selected using 5 μg/mL puromycin (sc-108071, Santa Cruz Biotechnology, Damascus, MD, USA) for 7 days. Cell culture and cell treatment RAW264.7

(12) Involvement of c-Myc/WWP1/TRIM65 Axis in Renal FibrosisBiomoleculesMarch 2, 2026Sonia Mazumder, Cody Gifford, Jiaqi Tang, Fortis Gaba, Varsha Mondal, Roel Goldschmeding, Rohan Samarakoon, Paul J. Higgins5% FBS; 5 units/mL penicillin + 5 µg/mL streptomycin) containing 5 µg/mL puromycin dihydrochloride (sc-108071, Santa Cruz Biotechnology, Dallas, TX, USA). Media were changed every 3 days to maintain the appropriate

(13) Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cellsSTAR ProtocolsMarch 1, 2026Pei-Li Tseng, Weiwei Sun, Jiawei Li, Mark O. Collins, Kai S. ErdmannZeocin Selection Reagent,Gibco,#R25001 Hygromycin B,Gibco,#10687010 Puromycin dihydrochloride,Santa Cruz,#sc-108071 Tetracycline hydrochloride,Sigma-Aldrich,#T7660 Biotin,Sigma-Aldrich,#B4501 "Collagen I, rat tail",Gibco,#A1048301 "Hoechst

(14) TXNIP-Deficiency and Prdx6 Delivery Inhibit Aging/Oxidative Stress–Driven TXNIP-Nlrp3 Inflammasome Activation and Mitigate Pyroptosis in Lens Epithelial CellsAntioxidants (Basel)January 28, 2026Bhavana Chhunchha, Eri Kubo, Renuka R. Manoharan, Rakesh Kumar, Dhirendra P. Singhcomplete media. Lentiviral-infected mLECs were subcultured and treated with puromycin dihydrochloride (sc-108071, Santa Cruz Biotechnology, Inc., Dallas, TX, USA) for selection of stable cell lines. Puromycin-resistant

(15) Myosin-X Acts Upstream of L-Plastin to Drive Stress-Induced Tunneling NanotubesCellsJanuary 24, 2026Ana Ramirez Perez, Joey Tovar, Karine GoussetDallas, TX, USA, sc-108060), Polybrene (sc-134220) reagent and puromycin dihydrochloride (Santa Cruz, sc-108071) were from Santa Cruz Biotechnology, Inc., and were used according to the manufacturer’s instructions.

(16) Targeting RAD52 overcomes PARP inhibitor resistance in preclinical Brca2 -deficient ovarian cancer modelbioRxivJanuary 16, 2026Yukihide Ota, Vijayalaxmi Gupta, Bisiayo E. Fashemi, Moreniola Akande, Preedia Babu, Prasanth Thuthika, Maia L. Elizagaray, Lulu Sun, Brooke Sanders, Lindsay M Kuroki, et al.lentiviruses and 5 μg/mL polybrene (Santa Cruz, sc-134220) and selected with 8 μg/mL puromycin (Santa Cruz, sc-108071) for three days. Cells transfected with scrambled shRNA (Santa Cruz, sc-108080) were used as controls. Immunofluorescence Immunofluorescence

(17) Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphataseThe EMBO JournalJanuary 3, 2026Hongbin Yang, Paul Smith, Yingying Ma, Emily Southworth, Varun Gopala Krishna, Beatrice Salerno, Joseph Rowland, Alexander E P Loftus, Domenico Grieco, Iolanda Vendrell, et al.for mammalian,Sigma-Aldrich,P8340 Protein A/G agarose beads,Santa Cruz,sc-2003 Puromycin,Santa Cruz,sc-108071 Sodium dodecyl sulfate (SDS),Sigma-Aldrich,74255-250G Strep-Tactin™ Superflow™ High Capacity Resin,IBA

(18) PHLDA1 silencing in IMR-32 human neuroblastoma cells results in ABCB1 overexpression, augments chemoresistance and leads to increased growth of tumorsScientific reportsDecember 22, 2025Kudrycka M, Horwacik I, Brożyna AA, Żywicka M, Durbas M, Rokita H.sodium pyruvate and 50 µg/ml gentamycin) supplemented with the selective antibiotic 0.5 µg/ml puromycin (sc-108071; Santa Cruz Biotechnology). For the CHP-134 neuroblastoma cell line, PHLDA1-silenced S6 and S17 clones

(19) Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid LeukemiaCancer ResearchNovember 21, 2025Johanna Eriksson, Shuyu Zheng, Mihaela Popa, Jie Bao, Jun Dai, Wenyu Wang, Emmet McCormack, Anna Vähärautio, Jing Tangconditions o/n, after which cells were washed and grown for 3 days before adding 0.5 ug/ml puromycin (#sc-108071, Santa Cruz Biotechnology, Dallas, TX, USA) for 9 days to remove cells without barcodes. Barcoded cells

(20) CDK12 regulates cellular metabolism to promote glioblastoma growthJCI InsightNovember 10, 2025Jeong-Yeon Mun, Chang Shu, Qiuqiang Gao, Zhe Zhu, Hasan O. Akman, Mike-Andrew Westhoff, Georg Karpel-Massler, Markus D. Siegelin(Santa Cruz Biotechnology, sc-134220) and were selected with 0.5–2 μg/μL puromycin (Santa Cruz Biotechnology, sc-108071). Cell viability assay. Cell viability experiments were performed on GBM22 and U251 GBM cell lines,

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Puromycin dihydrochloride Chemicals

Puromycin dihydrochloride from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Puromycin dihydrochloride from Santa Cruz Biotechnology, Inc.

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