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Puromycin
Puromycin dihydrochloride
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Puromycin dihydrochloride Chemicals
Puromycin dihydrochloride from Santa Cruz Biotechnology, Inc.
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Citations:
(415)
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Supplier Page from
Santa Cruz Biotechnology, Inc. for
Puromycin dihydrochloride
Description
Puromycin dihydrochloride
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Puromycin dihydrochloride
Company
Santa Cruz Biotechnology, Inc.
Price
$40.00
Supplier Page
View Company Product Page
Catalog Number
sc-108071
Quantity
25 mg
Type
Biochemical Reagents
Molecular Weight
544.43
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Santa Cruz Biotechnology, Inc.
10410 Finnell Street
Dallas
,
Texas
75220
United States
Phone
: 1-800-457-3801
831-457-3801
Company Profile
Website:
http://www.scbt.com/
Citations (415)
(1)
Loss of Peroxiredoxin 6 Drives Age-Related Klf9/NF-κB/Nlrp3 Inflammasome Activation and Pyroptosis: Therapeutic Rescue by Prdx6
Antioxidants (Basel)
April 23, 2026
Bhavana Chhunchha, Eri Kubo, Deepali Lehri, Dhirendra P. Singh
were added. Infected SRA-hLECs and mLECs were subcultured and treated with puromycin dihydrochloride (
sc-108071
,
Santa Cruz Biotechnology
) to select for stable integrants.
Puromycin
-resistant cells were maintained
(2)
SPNS2 exports sphingosine-1-phosphate and imports glucose
Nat Commun
April 20, 2026
Cynthia Weigel, Md Lokman Hossen, Ryan D. R. Brown, Can E. Senkal, Christopher D. Green, Jason Newton, Sumit Saha, Elisa N. D. Palladino, Bin Ni, Francesco S. Celi,
et al.
containing 2 µg/mL puromycin dihydrochloride, 300 µg/mL hygromycin B and 5 µg/mL blasticidin-S-HCl (#
sc-108071
, #
sc-29067
, #
sc-495389
,
Santa Cruz Biotechnology
). For the transduction of lentiviral particles, cells
(3)
Impact of SETD8/KMT5A overexpression on hepatocellular carcinoma progression and prognosis
PLoS One
April 13, 2026
Norihiko Suzaki, Shinya Hayami, Atsushi Miyamoto, Masashi Nakamura, Tomohiro Yoshimura, Kensuke Nakamura, Yoshinobu Shigekawa, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi,
et al.
the recommended protocol (plasmid DNA final concentration: 1 µg/ml). Subsequently, 1 µg/ml puromycin (
sc-108071
,
Santa Cruz Biotechnology
) was added to the cell lines that underwent
transfection
treatment, and they
(4)
Serglycin Cooperates with the Unfolded Protein Response Pathway and Inflammation to Drive Glioblastoma Cell Survival
Cells
April 9, 2026
Eleftherios N. Athanasopoulos, Chrysostomi Gialeli, Angeliki Natsiou, Dimitra Manou, Vassiliki T. Labropoulou, Achilleas D. Theocharis
protocol, as described previously [20].
Puromycin dihydrochloride
, at the optimal concentration 0.8 μg/mL (
sc-108071
,
Santa Cruz Biotechnology, Inc
., Heidelberg, Germany) was used for the selection and manufacture of
(5)
High-linear energy transfer radiation disrupts natural killer cell surveillance of senescent intestinal cells in the mouse intestine
Mol Biomed
April 7, 2026
Santosh Kumar, Shubhankar Suman, Heng-Hong Li, Jerry Angdisen, Kamal Datta, Albert J. Fornace
new medium, and antibiotic selection was initiated after 48 h using puromycin (1.0 µg/mL;
Santa Cruz
,
sc-108071
) or neomycin (400 µg/mL;
Santa Cruz
,
sc-255391
). Following 5 days of selection, cells were returned
(6)
Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia
Cancer Res
April 2, 2026
Johanna Eriksson, Shuyu Zheng, Mihaela Popa, Jie Bao, Jun Dai, Wenyu Wang, Emmet McCormack, Anna Vähärautio, Jing Tang
conditions o/n, after which cells were washed and grown for 3 days before adding 0.5 ug/ml puromycin (#
sc-108071
,
Santa Cruz Biotechnology
, Dallas, TX, USA) for 9 days to remove cells without barcodes. Barcoded cells
(7)
Cystinosin regulates Na+/H+ exchanger 3 trafficking and function in kidney proximal tubular cells
EMBO Reports
March 24, 2026
Veenita Khare, Jean-Claude Farré, Mouad Ait Kbaich, Céline J Rocca, Cynthia Tang, Xuan Ma, Kavya Biederman, Ioli Mathur, Rafael A Badell-Grau, Anusha Sivakumar,
et al.
albumin,
Invitrogen
,
A34786
AnnexinV,Invitrogen,331200 7-amino-actinomycin D (7-AAD),
Invitrogen
,
00-6993-50
Puromycin dihydrochloride
,
Santa cruz
,
sc-108071
Kidney FFPE tissue (non-
cystinosis
healthy donor),
Zyagen
,
HP-901
Miltenyi
LS columns
,
Miltenyi Biotec
,
130-042-401
Anti-Sca-1
(8)
WNT7B drives a program for pancreatic cancer subtype switching and progression
iScience
March 20, 2026
Joep Sprangers, Jeroen M. Bugter, Despina Xanthakis, Michiel Boekhout, Rutger N.U. Kok, Veerle E. Geurts, Hans Clevers, Lodewijk A.A. Brosens, Frederike Dijk, Maria J. Rodríguez Colman,
et al.
inhibitor),
Tocris
,
2939/10
Polybrene
(hexadimethrine bromide),Merck,3701-03-3
Puromycin
,
Santa Cruz
,
SC-108071
Matrigel,
Corning
,
356231
Basement Membrane
Extract (BME),
R&D Systems
,
3533-010-02
(RGF) TrypLE,Thermo
(9)
Nisin bacteriocin blocks T. denticola-triggered MMP2 activation and pathogen internalization via TLR2
Scientific Reports
March 11, 2026
Pachiyappan Kamarajan, Allan Radaic, Hossein Beheshti, Mishri Parikh, Sarah Lo, J Christopher Fenno, Yvonne L. Hernandez Kapila
lentiviral particles in 0.5 mL of serum-free media containing polybrene then selected in 5 µg/mL puromycin (
sc-108071
;
Santa Cruz Biotechnology
) for an additional 10 days32. Surviving cell colonies were picked and propagated
(10)
Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage
Nat Commun
March 9, 2026
Irina Poverennaya, Aliia Murtazina, Lei Li, Lorena Maili, Lukas Sourada, Luis Fernando Montano-Gutierrez, Rozalina Galimullina, Tobias Steinschaden, Marketa Kaiser, Tomas Zikmund,
et al.
Stable transduced cell pools were selected by two rounds of 5-day treatment with 2 µg/ml puromycin (#
sc−108071
,
Santa Cruz Biotechnology
). RNA extraction, reverse transcription and
qPCR
were performed as previously
(11)
DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis
Nature Communications
March 9, 2026
Wenchen Luo, Wei Xu, Qimeng Yin, Jieqiong Song, Jie Wang, Yian Guan, Jian Huang, Jian Yu, Kefeng Zou, Danfeng Jin,
et al.
Laboratories) for 24 h. At 48 h post-
infection
, RAW264.7 cells or BMDMs were selected using 5 μg/mL puromycin (
sc-108071
,
Santa Cruz Biotechnology
, Damascus, MD, USA) for 7 days.
Cell culture
and cell treatment RAW264.7
(12)
Involvement of c-Myc/WWP1/TRIM65 Axis in Renal Fibrosis
Biomolecules
March 2, 2026
Sonia Mazumder, Cody Gifford, Jiaqi Tang, Fortis Gaba, Varsha Mondal, Roel Goldschmeding, Rohan Samarakoon, Paul J. Higgins
5% FBS; 5 units/mL penicillin + 5 µg/mL streptomycin) containing 5 µg/mL puromycin dihydrochloride (
sc-108071
,
Santa Cruz Biotechnology
, Dallas, TX, USA). Media were changed every 3 days to maintain the appropriate
(13)
Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells
STAR Protocols
March 1, 2026
Pei-Li Tseng, Weiwei Sun, Jiawei Li, Mark O. Collins, Kai S. Erdmann
Zeocin Selection Reagent
,
Gibco
,#
R25001
Hygromycin B,
Gibco
,#
10687010
Puromycin dihydrochloride
,
Santa Cruz
,#
sc-108071
Tetracycline hydrochloride
,
Sigma-Aldrich
,#T7660 Biotin,Sigma-Aldrich,#B4501 "Collagen I, rat tail",
Gibco
,#
A1048301
"Hoechst
(14)
TXNIP-Deficiency and Prdx6 Delivery Inhibit Aging/Oxidative Stress–Driven TXNIP-Nlrp3 Inflammasome Activation and Mitigate Pyroptosis in Lens Epithelial Cells
Antioxidants (Basel)
January 28, 2026
Bhavana Chhunchha, Eri Kubo, Renuka R. Manoharan, Rakesh Kumar, Dhirendra P. Singh
complete media. Lentiviral-infected mLECs were subcultured and treated with puromycin dihydrochloride (
sc-108071
,
Santa Cruz Biotechnology, Inc
., Dallas, TX, USA) for selection of stable cell lines.
Puromycin
-resistant
(15)
Myosin-X Acts Upstream of L-Plastin to Drive Stress-Induced Tunneling Nanotubes
Cells
January 24, 2026
Ana Ramirez Perez, Joey Tovar, Karine Gousset
Dallas, TX, USA,
sc-108060
),
Polybrene
(
sc-134220
) reagent and puromycin dihydrochloride (
Santa Cruz
,
sc-108071
) were from Santa Cruz Biotechnology, Inc., and were used according to the manufacturer’s instructions.
(16)
Targeting RAD52 overcomes PARP inhibitor resistance in preclinical Brca2 -deficient ovarian cancer model
bioRxiv
January 16, 2026
Yukihide Ota, Vijayalaxmi Gupta, Bisiayo E. Fashemi, Moreniola Akande, Preedia Babu, Prasanth Thuthika, Maia L. Elizagaray, Lulu Sun, Brooke Sanders, Lindsay M Kuroki,
et al.
lentiviruses
and 5 μg/mL polybrene (
Santa Cruz
,
sc-134220
) and selected with 8 μg/mL puromycin (
Santa Cruz
,
sc-108071
) for three days. Cells
transfected
with scrambled
shRNA
(
Santa Cruz
,
sc-108080
) were used as controls.
Immunofluorescence
Immunofluorescence
(17)
Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphatase
The EMBO Journal
January 3, 2026
Hongbin Yang, Paul Smith, Yingying Ma, Emily Southworth, Varun Gopala Krishna, Beatrice Salerno, Joseph Rowland, Alexander E P Loftus, Domenico Grieco, Iolanda Vendrell,
et al.
for mammalian,Sigma-Aldrich,P8340 Protein A/G agarose beads,
Santa Cruz
,
sc-2003
Puromycin
,
Santa Cruz
,
sc-108071
Sodium dodecyl sulfate (SDS),Sigma-Aldrich,74255-250G Strep-Tactin™ Superflow™ High Capacity Resin,IBA
(18)
PHLDA1 silencing in IMR-32 human neuroblastoma cells results in ABCB1 overexpression, augments chemoresistance and leads to increased growth of tumors
Scientific reports
December 22, 2025
Kudrycka M, Horwacik I, Brożyna AA, Żywicka M, Durbas M, Rokita H.
sodium pyruvate and 50 µg/ml gentamycin) supplemented with the selective antibiotic 0.5 µg/ml puromycin (
sc-108071
;
Santa Cruz Biotechnology
). For the CHP-134
neuroblastoma
cell line,
PHLDA1
-silenced S6 and S17
clones
(19)
Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia
Cancer Research
November 21, 2025
Johanna Eriksson, Shuyu Zheng, Mihaela Popa, Jie Bao, Jun Dai, Wenyu Wang, Emmet McCormack, Anna Vähärautio, Jing Tang
conditions o/n, after which cells were washed and grown for 3 days before adding 0.5 ug/ml puromycin (#
sc-108071
,
Santa Cruz Biotechnology
, Dallas, TX, USA) for 9 days to remove cells without barcodes. Barcoded cells
(20)
CDK12 regulates cellular metabolism to promote glioblastoma growth
JCI Insight
November 10, 2025
Jeong-Yeon Mun, Chang Shu, Qiuqiang Gao, Zhe Zhu, Hasan O. Akman, Mike-Andrew Westhoff, Georg Karpel-Massler, Markus D. Siegelin
(
Santa Cruz Biotechnology
,
sc-134220
) and were selected with 0.5–2 μg/μL puromycin (
Santa Cruz Biotechnology
,
sc-108071
).
Cell viability assay
. Cell viability experiments were performed on GBM22 and U251 GBM cell lines,
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Reviews
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Puromycin dihydrochloride from Santa Cruz Biotechnology, Inc.
Supplier Page
View Company Product Page
$40.00
Product Specs
Company Info
Citations
Reviews
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