A-375 [A375] from ATCC

Product Specs
ItemA-375 [A375]
CompanyATCC
Price $495.00Supplier Page View Company Product Page
Catalog NumberCRL-1619
TypeCell Biology
SpeciesHomo sapiens
TissueSkin
Cell LineA-375
Validated Species ReactivityHuman (Hu)
Tissue (standardized)Skin
ApplicationsThis cell line is a suitable transfection host. This cell line is also the ideal control for NRAS mutant-A375 isogenic cell line (ATCC CRL-1619IG-2)
Age54 years
DiseaseMalignant Melanoma

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulationLife Science AllianceMay 1, 2026Noemi Garcia Garcia, Thanh Ha Vy Nguyen, Dane Richey, Emily F Cox, Jon Coca Juaristi, Cody Ashby, Analiz Rodriguez, Katie R Ryangroupings. Cell culture Authenticated A549 (CCL185) and H460 (HTB-177) lung adenocarcinoma cells and A375 (CRL1619) melanoma cells were obtained from the ATCC. For primary patient-derived brain metastatic non–small-cell lung carcinoma

(2) Early-stage multi-cancer detection through a plasma extracellular vesicle protein signatureCell Reports MedicineApril 21, 2026Richard J. Lobb, Quan Zhou, David Fielding, Kekoolani S. Visan, Alain Wuethrich, Jing Wang, Youran Hu, Emma L. Norris, Marcus L. Hastie, Sarah Everitt, et al.CVCL_0623 PC-3,ATCC,CRL-1435; RRID: CVCL_0035 LNCaP clone FGC,ATCC,CRL-1740; RRID: CVCL_1379 A375,ATCC,CRL-1619; RRID: CVCL_0132 MAMEL65,ATCC,RRID: CVCL_A200 SKMEL28,ATCC,HTB-72; RRID: CVCL_0526 OE19,Sigma-Aldrich,Cat#

(3) A harmless-to-harmful switchable and spatiotemporally activated nano-CRISPR hierarchically amplifies ferroptosis in melanomaCell Reports MedicineApril 21, 2026Chunqing Ou, Xianzhou Huang, Dongxue Huang, Rui Luo, Ruhan Chen, Xinchao Li, Xinyue Wu, Qinjie Wu, Changyang Gong,Experimental models: Cell lines,Experimental models: Cell lines ,, B16-F10,ATCC,Cat# CRL-6475 A375,ATCC,Cat# CRL-1619 CT26,ATCC,Cat# CRL-2638 Panc02,"Cell Bank of the Committee on Type Culture Collection, Chinese Academy

(4) PALINCODE: Recording cell lineage with ternary palindromic CRISPR bitsbioRxivApril 19, 2026Maryam Fathi, Aidan Cook, Bagheri Bagheri, Tyler Curiel, Aaron McKennaCell culture We performed all tissue culture experiments with HEK293T (ATCC #CRL-3216) and A375 cells (ATCC #CRL-1619). We maintained HEK293T and A375 in complete DMEM, Dulbecco's modified eagle medium (DMEM, Corning #10013CM)

(5) Mathematical modelling of ribosome competition informs testable treatment strategies for drug-tolerant cancer persister cellsiScienceApril 17, 2026Xinpu Tang, Yuqing Wang, Yi Pu, Kaixiu Li, Zheyu Ding, Mengyao Wang, Luis Almeida, Michael Cerezo, Yarong Cao, Caroline Robert, et al.Experimental models: Cell lines,Experimental models: Cell lines,Experimental models: Cell lines ,, A375,ATCC,Cat.#CRL-1619 SK-MEL-28,ATCC,Cat.#HTB-72 QBC939,ATCC,Cat.#PDM-219 WM983B,"L. Larue (Institut Curie, France)",N/A HEK293T,ATCC,Cat.#CRL-3519 YUMM1.7,ATCC,Cat

(6) DNA Binding, DNA Photocleavage, Molecular Docking Studies and Photo-Induced Effect on Melanoma Cells of 2-Methyl-3-OR Quinazolinone DerivativesBiomoleculesApril 8, 2026Chrysoula Mikra, Stella Malichetoudi, Dimitrios Arampatzis, Ioanna Laskari, Maria Koffa, Ewelina Wieczorek-Szweda, Katerina R. Katsani, George Psomas, Konstantina C. Fylaktakidouthe docking results and interactions between DNA and compounds. 2.6. Cell Culture Experiments A375 (CRL-1619, ATCC) melanoma cells and HaCaT (300493, Cytion) immortalized keratinocytes were cultured under aseptic

(7) High-content CRISPR activation screens identify synthetically lethal RNA-based mechanisms to sensitize cancer cells to targeted T cell cytotoxicityNat GenetApril 7, 2026Reece Villarin Akana, Jeehyun Yoe, Olivia Laveroni, Chang Sun, Young-Min Kim, Livnat Jerbybreast adenocarcinoma cell line MCF7 were obtained from American Type Culture Collection (ATCC, cat. no. CRL-1619) and Sigma-Aldrich (cat. no. 86012803), respectively. A375 and MCF7 cells were cultured in Dulbecco’s

(8) HSP90 inhibition potentiates oxidant-based antimelanoma action of novel thioquercetin derivatives by compromising AhR/CYP1A1 pathwayApoptosisMarch 28, 2026Wojciech Witkowski, Julia Słaby, Maciej Wnuk, Paulina Stec, Piotr Piotrowski, Michał Żebrowski, Martyna Cybularczyk-Cecotka, Anna Deręgowska, Nadezhda Romanchikova, Pawel Zayakin, et al.conditions, and treatments Four melanoma cell lines were used, namely A375 (malignant melanoma/epithelial, CRL-1619™, ATCC, Manassas, VA, USA), MM370 (malignant melanoma/epithelial, 10092316, CBA-1348, distributed by

(9) Discovery of Two Novel Pyrazole Derivatives as Anticancer Agents Targeting Tubulin Polymerization and MAPK Signaling PathwaysOncology ResearchMarch 23, 2026Denisse A. Gutierrez, Elisa Robles-Escajeda, Jose A. Lopez-Saenz, Robert A. Kirken, Edgar A. Borrego, Ana P. Betancourt, Soumya Nair, Sourav Roy, Armando Varela-Ramirez, Renato J. AguileraLM2-4 [15], MDA-MB-468 (ATCC, HTB-132), MCF-7 (ATCC, HTB-22), PANC-1 (ATCC, CRL-1469), A375 (ATCC, CRL-1619), HEPG2 (ATCC, HB-8065), HeLa (ATCC, CCL-2) and HS-27 (ATCC, CRL-1634). Additionally, the MCF-7 cells

(10) Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functionseLifeMarch 20, 2026Yu Hong, Xiaofang Si, Wenjing Liu, Xueying Mai, Yu Zhanglaboratory of Dr. Zhaoqing Ba (National Institute of Biological Sciences, Beijing). A375 cell line (ATCC: CRL-1619) was provided by the laboratory of Dr. Feng Shao (National Institute of Biological Sciences, Beijing).

(11) Androgen receptor-dependent DRAM1 activation drives autophagic resistance to BRAF inhibitors in BRAFV600-mutant melanomaCell Death DisMarch 16, 2026Ding Zhi, Baojin Wu, Junyi Yang, Daohe Wang, Jing Qiao, Fanli Guopopulation. Methods Cell lines and cultures Melanoma cell lines SH-4 (CRL-7724), SK-MEL-2 (HTB-68), A375(CRL-1619), WM-266-4(CRL-1676) and SK-MEL-28 (HTB-72) were purchased from ATCC. WM793 (WM793-01-0001) was sourced

(12) Riboflavin metabolism shapes FSP1-driven ferroptosis resistanceNature Cell BiologyMarch 13, 2026Vera Skafar, Izadora de Souza, Biplab Ghosh, Ancely Ferreira dos Santos, Florencio Porto Freitas, Zhiyi Chen, Shibo Sun, Merce Donate Castillo, Palina Nepachalovich, Lars Seufert, et al.lines HT1080, A375, MDA-MB-231, MDA-MB-436, A549 and H460 were purchased from ATCC (cat. nos. CCL-121, CRL-1619, CRM-HTB-26, HTB-130, CRM-CCL-185 and HTB-177, respectively) and PC-9 cells were purchased from Sigma

(13) The impact of ERAP1 inhibition on metabolite homeostasis of melanoma cellsScientific ReportsMarch 7, 2026Aroosha Raja, Martha Nikopaschou, Joke H. de Boer, Jeannette Ossewaarde-van Norel, Anna Artati, Michael Witting, Efstratios Stratikos, Jonas J. W. Kuiperapplications aiming to regulate adaptive immune responses. Methodology Cell culture A375 wild type (CRL-1619, ATCC) and ERAP1 KO cells (Clone 1B12, previously generated in house19 were cultured in Dulbecco’s Modified

(14) Disruption of tRNA threonylation triggers RIG-I mediated anti-tumour immune responseNature CommunicationsFebruary 25, 2026Cléa Dziagwa, Christian Seca, Coralie Capron, Chloe Maurizy, Ning An, Denis Heusdens, Timothy Budden, Lorena Martin-Morales, Miguel Susaeta Ruiz, Elodie Renaude, et al.a humidified incubator at 37 °C with 5% CO2. Melanoma cell line B16F10 (ATCC CRL-6475), A375 (ATCC CRL-1619) and Lenti-X293 T (Sigma-Aldrich) were grown in Dulbecco’s modified Eagle’s medium (DMEM, LONZA) supplemented

(15) Hypoxia restores the acidosis-induced inhibition of cancer cell disseminationCell ReportsFebruary 24, 2026Se Jong Lee, Alice Amitrano, Qinling Yuan, Debanik Choudhury, Konstantin Stoletov, Bhawana Agarwal, Avery Tran, Inês Godet, James McCann, Ryan Huizar, et al.pHred,(Bera et al.)20,N/A HT1080 wild-type,ATCC,Cat # CCL-121 HCT116,ATCC,Cat # CCL-247 A375,ATCC,Cat # CRL-1619 HOS,ATCC,Cat # CRL-1543 Experimental models: Organisms/strains,Experimental models: Organisms/strains,Experimental models

(16) A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppressionCellFebruary 19, 2026Zhangchuan Xia, Xin Yang, Sviatlana N. Samovich, Yulia Y. Tyurina, Vladimir A. Tyurin, Ning Kon, Jiankang Zhang, Xuejun Jiang, Brent R. Stockwell, Jian Jin, et al.,Experimental models: Cell lines Human: NCI-H1299,ATCC,CRL-5803 Human: HEK293T,ATCC,CRL-3216 Human: A375,ATCC,CRL-1619 Human: A549,ATCC,CCL-185 Human: U2OS,ATCC,HTB-96 Human: MIAPaCa2,Kenneth Olive Lab (Columbia University),N/A Human:

(17) Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic driversCell Reports MedicineFebruary 17, 2026Jeffrey Wang, Jung Min Suh, Brian J. Woo, Albertas Navickas, Kristle Garcia, Keyi Yin, Lisa Fish, Taylor Cavazos, Benjamin Hänisch, Daniel Markett, et al.oncRNA.ch17.67,This paper,N/A HCC1806 oncRNA.ch17.67,This paper,N/A MCF7,ATCC,Cat#HTB-22 A375,ATCC,Cat#CRL-1619 LS174T,ATCC,Cat#CL-188 PANC-1,ATCC,Cat#CRL-1469 MDA-MB-453,ATCC,Cat#HTB-131 Hs 707(A).T,ATCC,Cat#CRL-7448 HEK293,ATCC,Cat#CRL-1573 A2058,ATCC,Cat#CRL-3601 HCC-44,DSMZ,Cat#ACC534 NCI-H23,ATCC,Cat#CRL-5800 NCI-H1299,ATCC,Cat#CRL-5803 NCI-H358,ATCC,Cat#CRL-5807 BxPC-3,ATCC,Cat#CRL-1687 LNCaP,ATCC,Cat#CRL-1740 ZR-75-1,ATCC,Cat#CRL-1500 K-562,ATCC,Cat#CCL-243 MIA PaCa-2

(18) 3D-Printed Microneedle Patch for the Treatment of Melanoma via Synergistic Chemotherapy and Photothermal TherapyACS Applied Bio MaterialsFebruary 16, 2026Hilal Yilmaz, Louna Karzoun, Berfin Ilayda Ozturk Guzelcan, Hakan Sahin, Yagmur Kazancioglu, Mohammad Yaman Habra, Esra Yuca Yilmaz, Elif Guzel, Oguzhan Gunduz, Yavuz Nuri Ertas, et al.using ImageJ software. 2.2.14 In Vitro Cytotoxicity Analysis The human melanoma cell line A-375 (CRL-1619, ATCC) was used. The frozen cells were thawed quickly, seeded into DMEM/F12 medium containing 10% fetal bovine serum (FBS

(19) Anticancer Activity of Microbial Biosurfactants Amphisin and Viscosinamide Against Melanoma CellsMoleculesFebruary 14, 2026Dominika Jama, Zbigniew Lazar, Tomasz Janekfatty acid (3-OH C10:0; MW 1124.7 g/mol). 3.2. Cell Culture Conditions Human melanoma A375 (ATCC CRL-1619; Manassas, VA, USA) and mouse melanoma B16 4A5 cells were maintained in Dulbecco’s Modified Eagle Medium

(20) Exploring How Workflow Variations in Denaturation-Based Assays Impact Global Protein–Protein Interaction PredictionsMolecular & Cellular ProteomicsFebruary 1, 2026Tavis J. Reed, Laura M. Haubold, Josiah E. Hutton, Olga G. Troyanskaya, Ileana M. CristeaPython and Microsoft PowerPoint. Cell lines, Virus Strains, Primary Culture, and Infections A375 (ATCC CRL-1619) and A549 cells (ATCC CCL-185) were cultured in complete growth medium (DMEM supplemented with 10% fetal bovine serum [FBS

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A-375 [A375]

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A-375 [A375] from ATCC

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