NT8 v4® Drop Setter Liquid Handler from FORMULATRIX

Product Specs
ItemNT8 v4^® Drop Setter Liquid Handler
CompanyFORMULATRIX
Price Get Pricing Get Quote for this Product
Catalog NumberNT8 v4
Dimensions(WxDxH) 25.7 x 20.1 x 16.9 in.
QuantityEA
Electrical Requirements110 to 240 V

Add to Compare List

FORMULATRIX

5 DeAngelo Drive

Bedford, MA 01730

United States

Phone: +1 781 788 0228
Fax: +1 781 207 5522

Email: info@formulatrix.com

Company Profile

Website: https://formulatrix.com/

(1) High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic actionCommunications BiologyDecember 1, 2022Igor Melnikov, Philipp Orekhov, Maksim Rulev, Kirill Kovalev, Roman Astashkin, Dmitriy Bratanov, Yury Ryzhykau, Taras Balandin, Sergei Bukhdruker, Ivan Okhrimenko, et al.glass sandwich plates (Marienfeld, Germany) and covered with 800 nl of precipitant solution using the NT8-LCP crystallisation robot (Formulatrix, USA). Crystals were grown at 20 °C and reached their final sizes

(2) Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunitCommunications BiologyDecember 1, 2022Nicholas K. Hurlburt, Leah J. Homad, Irika Sinha, Madeleine F. Jennewein, Anna J. MacCamy, Yu-Hsin Wan, Jim Boonyaratanakornkit, Anton M. Sholukh, Abigail M. Jackson, Panpan Zhou, et al.was performed by sitting-drop vapor-diffusion in the MCSG Crystallization Suite (Anatrace) using a NT8 drop setter (Formulatrix). Poorly diffracting crystals grew in MCSG-3 well B1 and were optimized using

(3) Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10The Journal of biological chemistryDecember 1, 2022Sheehan CT, Hampton TH, Madden DR.pH 7.5) and equilibrated by vapor diffusion with 50 μl of well solution. The drop was set up using a NT8 drop setter (Formulatrix) and the well solution was from the Wizard Classic I&II High-Throughput Screen

(4) Crystal structure of semi-synthetic obelin-v after calcium induced bioluminescence implies coelenteramine as the main reaction productSci RepNovember 15, 2022Pavel V. Natashin, Elena V. Eremeeva, Mikhail B. Shevtsov, Margarita I. Kovaleva, Sergey S. Bukhdruker, Daria A. Dmitrieva, Dmitry V. Gulnov, Elena V. Nemtseva, Valentin I. Gordeliy, Alexey V. Mishin, et al.96-well crystallization plates (SPT Labtech, UK). For screening initial crystallization conditions, the NT8 crystallization robot (Formulatrix, USA) and commercially available crystallization screening kits JCSG,

(5) Structural insights into light-driven anion pumping in cyanobacteriaNature CommunicationsOctober 29, 2022R. Astashkin, K. Kovalev, S. Bukhdruker, S. Vaganova, A. Kuzmin, A. Alekseev, T. Balandin, D. Zabelskii, I. Gushchin, A. Royant, et al.96-well LCP glass sandwich plate (Marienfeld) and overlaid with 600 nL of precipitant solution using the NT8 crystallization robot (Formulatrix). The best crystals of chloride-bound form (red) were obtained with

(6) Chemical Toolkit for PARK7: Potent, Selective, and High-ThroughputJournal of Medicinal ChemistryOctober 13, 2022Yuqing Jia, Robbert Q. Kim, Raymond Kooij, Huib Ovaa, Aysegul Sapmaz, Paul P. Geurinkcrystallization with 0.1 μL of protein solution and 0.1 μL of mother liquor using nanoliter dispensing robot NT8 (Formulatrix). Specific crystallization conditions for each PARK7 complex are reported below. Crystals

(7) GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A_2A Adenosine ReceptorJournal of Medicinal ChemistrySeptember 8, 2022Anna Shiriaeva et al.and overlaid with 800 nL of precipitant in 96-well LCP glass sandwich plates (Marienfeld) using the NT8-LCP system (Formulatrix). Crystallization hits were obtained in 0.1 M HEPES (pH 5.3), 0.05 M sodium

(8) PH domain-mediated autoinhibition and oncogenic activation of AkteLifeAugust 15, 2022Hwan Bae, Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta Salguero, Michael J Eck, Haribabu Arthanari, Philip A Coledye dilutions in assay buffer (25 mM HEPES pH = 7.5, 150 mM NaCl, 1 mM TCEP) were first prepared by a NT8 liquid handler (Formulatrix) followed by addition of 10 μM PH domain. Dilution series were ×0.2–30 SyproOrange

(9) Structural basis for receptor selectivity and inverse agonism in S1P5 receptorsNature CommunicationsAugust 12, 2022Elizaveta Lyapina et al.96-wells glass sandwich plates (Marienfeld) in 40 nl drops and covered with 900 nl precipitant using an NT8-LCP robot (Formulatrix) to grow crystals for synchrotron data collection. To prepare crystals for XFEL

(10) Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like ProteaseJournal of Medicinal ChemistryJune 9, 2022Chamandi S. Dampalla et al.compound and incubating the complexes on ice for 1 h. All crystallization experiments were setup using an NT8 drop-setting robot (Formulatrix, Inc.) and UVXPO MRC (Molecular Dimensions) sitting drop vapor diffusion

(11) In situ crystal data-collection and ligand-screening system at SPring-8Acta Crystallographica Section F Structural Biology CommunicationsJune 1, 2022Hideo Okumura et al.protein solution and crystallization solution on an In Situ-1 Crystallization Plate (MiTeGen) using the NT8 drop setter (Formulatrix). The sitting-drop vapor-diffusion method was used for all crystallization

(12) High-Throughput Evaluation of Emission and Structure in Reduced-Dimensional PerovskitesACS Central ScienceMay 25, 2022Husna Anwar, Andrew Johnston, Suhas Mahesh, Kamalpreet Singh, Zhibo Wang, Douglas A. Kuntz, Isaac Tamblyn, Oleksandr Voznyy, Gilbert G. Privé, Edward H. Sargentcrystallization plates (three-well Intelliplates, Art Robbins Instruments, Figure 1a) with a Formulatrix NT8 fluid dispenser (Figure 1b). Antisolvents were added manually to the reservoirs of the synthesis plates

(13) Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domainScience AdvancesMay 6, 2022Matthew D. Gray et al.Hampton Crystal HT, ProPlex HT-96, and Wizard Precipitant Synergy no. 2 crystallization screens. The NT8 robotic system (FORMULATRIX) was used to set initial sitting drop crystallization trials. Following

(14) Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturationbioRxivApril 13, 2022Nicholas K. Hurlburt, Yu-Hsin Wan, Andrew B. Stuart, Junli Feng, Andrew T. McGuire, Leonidas Stamatatos, Marie Pancerafor initial crystal screening by sitting-drop vapor-diffusion in the MCSG Suite (Anatrace) using a NT8 drop setter (Formulatrix). Diffracting crystals were obtained in a mother liquor (ML) containing 0.2M

(15) The stem rust effector protein AvrSr50 escapes Sr50 recognition by a substitution in a single surface‐exposed residueNew PhytologistApril 1, 2022Diana Ortiz et al.of 200 nl protein solution equilibrated against 200 nl of reservoir solution, were prepared using a NT8®‐Drop Setter robot (Formulatrix, Bedford, MA, USA). The drops were monitored and imaged using the Rock Imager

(16) The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malariaCell ReportsFebruary 15, 2022Lawrence T. Wang et al.vapor-diffusion in the MCSG Crystallization Suite (Anatrace) and ProPlex (Molecular Dimensions) using a NT8 drop setter (Formulatrix). For apo-L9, crystals grew in ProPlex E5 and diffracting crystals were harvested

(17) A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric AssembliesFrontiers in Molecular BiosciencesFebruary 8, 2022Erin Skeens, Georgios Pantouris, Dilip Shah, Ramu Manjula, Michael J. Ombrello, N. Karl Maluf, Vineet Bhandari, George P. Lisi, Elias J. Lolisof Y99C MIF, Structure Determination, and Characterization of Solvent Channel Using the Formulatrix NT8 robot, 400 nl of 18 mg/ml protein was mixed with 200 nl reservoir solution (2 M ammonium sulfate, 3%

(18) Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based StudiesJournal of Medicinal ChemistryDecember 23, 2021Chamandi S. Dampalla et al.mg/mL (0.28 mM) for crystallization screening. All crystallization experiments were set up using an NT8 drop-setting robot (Formulatrix Inc.) and UVXPO MRC (Molecular Dimensions) sitting drop vapor diffusion

(19) Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysisNucleic Acids ResearchDecember 16, 2021Brittany L Carroll, Karl E Zahn, John P Hanley, Susan S Wallace, Julie A Dragon, Sylvie Doubliécondition F12 (0.2 M NaCl, 0.1 M HEPES pH 7.5, 25% PEG 3350) set in a 96-well sitting drop plate by the NT8 drop setter (Formulatrix). Both hNTHL1Δ63 and hNTHL1Δ63 SeMet crystals were grown in 24-well hanging

(20) Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn2+ ionsCommunications BiologyDecember 1, 2021Vladislav A. Lushpa, Marina V. Goncharuk, Cong Lin, Arthur O. Zalevsky, Irina A. Talyzina, Aleksandra P. Luginina, Daniil D. Vakhrameev, Mikhail B. Shevtsov, Sergey A. Goncharuk, Alexander S. Arseniev, et al.1 : 20. Crystallization was done by a vapor diffusion method with HR2-122 screen (Hampton Research) at NT8 robot (Formulatrix), the protein : precipitant ratio was 1 : 1, and final drop volume was 300 nL. Plates

Be the First to Write a Review!

NT8 v4^® Drop Setter Liquid Handler

NT8 v4^® Drop Setter Liquid Handler from FORMULATRIX

Description

FORMULATRIX

Citations (140)

Reviews

NT8 v4^® Drop Setter Liquid Handler from FORMULATRIX

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map