Description
Expand your rare cell research with the Genesis Cell Isolation system and Celselect Slides™ – a benchtop solution designed for easy, efficient and gentle sized-based capture of rare cells including circulating tumor cells (CTCs), immune cells, among others found in liquid biopsy samples.
The Genesis Cell Isolation System, used with Celselect Slides™, enables size-based selection and capture of single cells 8–30 µm, such as CTCs, rare cells, cultured cells, or cells in mixed populations. It is compatible and accepts a variety of liquid sample types, including body fluids (liquid biopsy), culture media and other sample types.
The Genesis System delivers samples from an input port into fluidic channels within the Celselect Slides™. Cells move along these channels, which connect to 140,800 individual microchambers for cell capture. Cells and other fluid components that are <8 µm flow through a bottom pore in each microchamber, while cells 8–30 µm are retained within microchambers. The gentle capture process retains cell native biology and is highly efficient, with blood samples showing a 99.9% elimination rate of RBCs, WBCs and other components. Once cells are captured, they may be stained or immunolabeled on-slide and visualized directly using microscopy. Alternatively, captured cells may be recovered in bulk and cultured or used for a variety of downstream applications (e.g. NGS, dPCR, qPCR, flow cytometry, etc.).
Features: - Capture mechanism:
- Efficiently and gently capture of 8-30 µm size rare cells with liquid biopsy samples
- Achieve 99% elimination rate of WBCs/RBCs from liquid biopsy blood samples
- One System Two Applications:
- Recover viable cells for downstream analysis (sequencing, digital PCR, qPCR, etc.) for further in vitro and in vivo analysis
- Capture and quantify cells using microscopy
- Customization: Tunable parameters enable diverse applications and samples