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Miscellaneous Human Cell Lines
NCI-H838 [H838]
NCI-H838 [H838] from ATCC
Be the first to write a review!
Citations:
(43)
Supplier Page
Supplier Page from
ATCC for
NCI-H838 [H838]
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Description
NCI-H838 [H838] is a cell line exhibiting epithelial morphology that was isolated from the lungs of a 59-year-old, White male with stage 3B adenocarcinoma. This product has applications in cancer research
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
NCI-H838 [H838]
Company
ATCC
Price
$551.00
Supplier Page
View Company Product Page
Catalog Number
CRL-5844
Type
Cell Biology
Species
Homo sapiens
Tissue
Lung
Cell Line
NCI-H838
Validated Species Reactivity
Human (Hu)
Tissue (standardized)
Lung
Age
59 years
Disease
Adenocarcinoma Non small cell lung cancer Stage 3B
Specifications/Features
Post freeze viability ≥ 50%
Add to Compare List
ATCC
10801 University Boulevard
Manassas
,
Virginia
20110-2209
United States
Phone
: (703) 365-2700
Fax: (703) 365-2701
Company Profile
Website:
http://www.atcc.org
Citations (43)
(1)
Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy
Nat Commun
April 12, 2026
Jana Samarin, Hana Nůsková, Piotr Fabrowski, Mona Malz, Eberhard Amtmann, Minerva J. Taeubert, Daniel Pastor-Flores, Daniel Kazdal, Roman Kurilov, Nicole de Vries,
et al.
CRL-5907
) were cultivated in
RPMI-1640
(Gibco). Other NSCLC cell lines (
ATCC
:
A549
CRM-CCL-185
and NCI-H838
CRL-5844
) were grown in low-glucose and high-glucose
DMEM
(Gibco), respectively. Resistance to cisplatin in H69CPR
(2)
The nuclear receptor NR6A1 plays an oncogenic role through reprogramming glycolysis in tumors
Biological Research
November 11, 2025
Xiaowen Liu, Ye Li, Xinxu Rao, Shun Xie, Zhuoxian Rong, Lifang Yang, Zenghui enghui Mao, Dan Li
cervical cancer
line
HeLa
(
ATCC
®
CRM-CCL-2
) and the intrahepatic
bile duct cancer
cell line TFK1 (
ATCC
®
CRL-5844
) were cultured in
Dulbecco’s modified Eagle’s medium (DMEM
, HyClone, USA) supplemented with 10% heat-inactivated
(3)
Rational Engineering of a Brevinin-2 Peptide: Decoupling Potency from Toxicity Through C-Terminal Truncation and N-Terminal Chiral Substitution
Antibiotics (Basel)
August 1, 2025
Aifang Yao, Zeyu Zhang, Zhengmin Song, Yi Yuan, Xiaoling Chen, Chengbang Ma, Tianbao Chen, Chris Shaw, Mei Zhou, Lei Wang
B2OS and its analogues. The
human
cancer
cell lines,
non-small-cell lung cancer
cell line, H838 (
ATCC
®
CRL-5844
™),
human
prostate
carcinoma
cell line,
PC-3
(
ATCC
®
CRL-1435
™),
human
breast cancer
cell line, MCF-7
(4)
Targeting transcription factors through an IMiD independent zinc finger domain
EMBO Molecular Medicine
May 14, 2025
Bee Hui Liu, Miao Liu, Sridhar Radhakrishnan, Meng-Yuan Dai, Chaitanya Kumar Jaladanki, Chong Gao, Jing Ping Tang, Kalpana Kumari, Mei Lin Go, Kim Anh L Vu,
et al.
SNU387 (
CRL-2237
), THLE2 (
CRL-2706
), THLE3 (
CRL-3583
),
A549
(
CRM-CCL-185
), H1299 (
CRL-5803
), H838 (
CRL-5844
), H552 (
CRL-5810
), H2030 (
CRL-5914
), and H661 (
HTB-183
)) were obtained from
ATCC
and grown according
(5)
Pan-KRAS inhibitors BI-2493 and BI-2865 display potent anti-tumor activity in tumors with KRAS wild-type allele amplification
Molecular Cancer Therapeutics
April 2, 2025
Antonio Tedeschi, Fiorella Schischlik, Francesca Rocchetti, Johannes Popow, Florian Ebner, Daniel Gerlach, Antonia Geyer, Valeria Santoro, Andrew S. Boghossian, Matthew G. Rees,
et al.
00478, RRID: CVCL_5065, MycoAlert September 01, 2022, STR profile September 21, 2022), NCI-H838 (
ATCC
CRL-5844
, RRID: CVCL_159, MycoAlert May 22, 2019, STR profile October 15, 2019), NCI-H661 (
ATCC
HTB-183
, RRID:
(6)
A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
Nat Commun
January 27, 2025
Veronica Rendo, Michael Schubert, Nicholas Khuu, Maria F. Suarez Peredo Rodriguez, Declan Whyte, Xiao Ling, Anouk van den Brink, Kaimeng Huang, Michelle Swift, Yizhou He,
et al.
Wald statistic of each gene in a set. Cell line information and
tissue culture
NCI-H838
(cat. no.
CRL-5844
;
ATCC
; male), NCI-H1650 (cat. no.
CRL-5883
;
ATCC
; male),
SK-LU-1
(cat. no.
HTB-57
;
ATCC
; female),
ZR-75-1
(7)
Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
Mol Cancer Ther
December 21, 2024
Antonio Tedeschi, Fiorella Schischlik, Francesca Rocchetti, Johannes Popow, Florian Ebner, Daniel Gerlach, Antonia Geyer, Valeria Santoro, Andrew S. Boghossian, Matthew G. Rees,
et al.
00478, RRID: CVCL_5065, MycoAlert September 01, 2022, STR profile September 21, 2022), NCI-H838 (
ATCC
CRL-5844
, RRID: CVCL_159, MycoAlert May 22, 2019, STR profile October 15, 2019), NCI-H661 (
ATCC
HTB-183
, RRID:
(8)
Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer
Cell Chemical Biology
December 19, 2024
Sasikumar Kotagiri, Nicholas Blazanin, Yuanxin Xi, Yanyan Han, Md Qudratullah, Xiaobing Liang, Yawen Wang, Poonam Pandey, Hira Mazhar, Truong Nguyen Lam,
et al.
H1793 (Cat#
CRL-5896
, female), H2023 (Cat#
CRL-5912
, male), H1693 (Cat#
CRL-5887
, female), H838 (Cat#
CRL-5844
, male) were obtained from
ATCC
. Routine testing was performed to ensure cells were free of
mycoplasma
(9)
Label-Free Single-Cell Cancer Classification from the Spatial Distribution of Adhesion Contact Kinetics
ACS Sensors
November 22, 2024
Balint Beres, Kinga Dora Kovacs, Nicolett Kanyo, Beatrix Peter, Inna Szekacs, Robert Horvath
solution. LCLC-103H
human
lung
large cell carcinoma
(ACC 384), H838
human
lung adenocarcinoma
(
ATCC
CRL-5844
), and
MDA-MB-231
and MCF-7
breast cancer
cells were cultured in
DMEM
supplemented with 10% FBS (Biowest
(10)
Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome
Microbiology Spectrum
October 3, 2024
Alexander Bontempo, Alexandra Chirino, Alireza Heidari, Alexandra Lugo, Satoru Shindo, Maria R. Pastore, Riccardo Madonia, Sibel A. Antonson, Cristina Godoy, Frank C. Nichols,
et al.
with the approved guidelines. Mammalian
cell cultures
293T
(
ATCC
CRL-3216
), ACE2 + 293, H838 (
ATCC
CRL-5844
), and TZM.bl cells were cultured in
DMEM
complemented with 10% SBF and 2% Penicillin (5,000 U/mL)/Streptomycin
(11)
Discovery and engineering of a novel peptide, Temporin-WY2, with enhanced in vitro and in vivo efficacy against multi-drug resistant bacteria
Scientific Reports
August 13, 2024
Fengting Liao, Zhuming Ye, Jinsheng Cheng, Jianhua Zhu, Xiaoling Chen, Xiaowei Zhou, Tao Wang, Yangyang Jiang, Chengbang Ma, Mei Zhou,
et al.
cancer
cell lines were chosen for this study:
human
non-small cell lung cancer
cell line, NCI-H838 (
ATCC
-
CRL-5844
);
human
glioblastoma
astrocytoma
cell line, U251MG (ECACC-09063001) and
human
breast cancer
cell line
(12)
Chimeric nanobody-decorated liposomes by self-assembly
Nature Nanotechnology
June 1, 2024
Md. Mofizur Rahman, Jing Wang, Guosheng Wang, Zhipeng Su, Yizeng Li, Yundi Chen, Jinguo Meng, Yao Yao, Lefei Wang, Stephan Wilkens,
et al.
(
HTB-30
),
MDA-MB-231
(
HTB-26
),
T24
(
HTB-4
),
HT-29
(
HTB-38
),
LS-174T
(
CL-188
), NCI-N87 (
CRL-5822
), NCI-H838 (
CRL-5844
) and NCI-H2170 cells (
CRL-5928
) were maintained in Dulbecco’s modified Eagle medium supplied with 10%
(13)
Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
Molecular Cell
May 16, 2024
Chao Mao, Guang Lei, Amber Horbath, Min Wang, Zhengze Lu, Yuelong Yan, Xiaoguang Liu, Lavanya Kondiparthi, Xiong Chen, Jun Cheng,
et al.
lines,, HEK293T,
ATCC
,Cat#
CRL-1573
HT-1080,
ATCC
,Cat#
CCL-121
NCI-H292,
ATCC
,Cat#
CRL-1848
HCC827
,
ATCC
,Cat#
CRL-2868
HEY-T30
,
ATCC
,Cat#
CRL-3252
NCI-N87,
ATCC
,Cat#
CRL-5822
PC-3
,
ATCC
,Cat#
CRL-1435
T-47D
,
ATCC
,Cat#
HTB-133
T98G,
ATCC
,Cat#
CRL-1690
DU 145
,
ATCC
,Cat#
HTB-81
NCI-H23,
ATCC
,Cat#
CRL-5800
NCI-H460,
ATCC
,Cat#
HTB-177
NCI-H838,
ATCC
,Cat#
CRL-5844
NCI-H1437,
ATCC
,Cat#
CRL-5872
NCI-H2126,
ATCC
,Cat#
CCL-256
HeLa
,
ATCC
,Cat#
CCL-2
Experimental models
:
(14)
miR-147b mediated suppression of DUSP8 promotes lung cancer progression
Oncogene
April 1, 2024
Turkowski K, Herzberg F, Günther S, Weigert A, Haselbauer T, Fink L, Brunn D, Grimminger F, Seeger W, Sültmann H,
et al
.
fetal bovine serum (FBS; Gibco) and 1%
penicillin-streptomycin (10,000 U/mL
,
Gibco
). H838 cells (
ATCC
CRL-5844
, American Type Culture Collection) and H1650 cells (
ATCC
CRL-5883
, American Type Culture Collection)
(15)
Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection
Bioconjugate Chemistry
October 18, 2023
Chiara Bellini, Emil Vergara, Fruzsina Bencs, Kinga Fodor, Szilvia Bősze, Denis Krivić, Bernadett Bacsa, Sára Eszter Surguta, József Tóvári, Rajko Reljic,
et al.
384),81,82 Calu-1
human
epidermoid carcinoma
(Sigma 93120818),83,84 H838
human
lung adenocarcinoma
(
ATCC
CRL-5844
),85 and Vero-E6
African green monkey
(Chlorocebus sabaeus) kidney
epithelium
cells (ECACC 85020206)
(16)
Antioxidants stimulate BACH1-dependent tumor angiogenesis
The Journal of clinical investigation
October 16, 2023
Wang T, Dong Y, Huang Z, Zhang G, Zhao Y, Yao H, Hu J, Tüksammel E, Cai H, Liang N,
et al
.
endpoint.
Cell culture
and reagents. The following
human
cell lines were used:
A549
(CRL-7909,
ATCC
); H838 (
CRL-5844
,
ATCC
); ZFN-generated
HIF1A
-
knockout
(HIF1α–/–) and control (HIF1α+/+)
A549 cells
(CLLS-1014, MilliporeSigma);
(17)
Discovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue
Computational and Structural Biotechnology Journal
May 6, 2023
Haixin Qin, Weimin Zuo, Lilin Ge, Shirley W.I. Siu, Lei Wang, Xiaoling Chen, Chengbang Ma, Tianbao Chen, Mei Zhou, Zhijian Cao,
et al.
carcinoma
cancer
cells,
PC-3
(
ATCC
®-CRL-1435TM),
human
non-small cell lung cancer
cells, H838(
ATCC
®-
CRL-5844
),
human
glioblastoma
/
astrocytoma
cancer
cells, U251MG (ECACC-09063001),
human
microvascular
endothelial cell
(18)
Protocol for 3D screening of lung cancer spheroids using natural products
SLAS Discovery
March 1, 2023
Virneliz Fernández Vega, Dong Yang, Luis Ortiz Jordán, Fei Ye, Louis Conway, Li Yun Chen, Justin Shumate, Pierre Baillargeon, Louis Scampavia, Glauco Souza,
et al.
Materials h522 (ATCC, Part#
CRL-5810
)h226 (
ATCC
, Part#
CRL-5826
)h1838 (
ATCC
, Part#
CRL-5899
)h838 (
ATCC
, Part#
CRL-5844
)h2030 (
ATCC
Part#
CRL-5914
)h358 (
ATCC
Part#
CRL-5807
)Calu1 (
ATCC
, Part#
HTB-54
)HCC1171 (Korean Cell
(19)
A Novel Strategy for the Design of Aurein 1.2 Analogs with Enhanced Bioactivities by Conjunction of Cell-Penetrating Regions
Antibiotics (Basel)
February 19, 2023
Fengting Liao, Yuping Chen, Anmei Shu, Xiaoling Chen, Tao Wang, Yangyang Jiang, Chengbang Ma, Mei Zhou, Tianbao Chen, Chris Shaw,
et al.
In this section, three
cancer
cell lines:
human
non-small-cell lung cancer
cell line, NCI-H838 (
ATCC
-
CRL-5844
);
human
glioblastoma
astrocytoma
cell line, U251MG (ECACC-09063001) and
human
breast cancer
cell line,
(20)
De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
Cell reports
September 27, 2022
Spears ME, Lee N, Hwang S, Park SJ, Carlisle AE, Li R, Doshi MB, Armando AM, Gao J, Simin K,
et al
.
RRID:CVCL_0317 "
NCI-H838
,
Human
Lung adenocarcinoma
","Laboratory of David Sabatini (MIT, USA)",
ATCC
Cat#
CRL-5844
; RRID:CVCL_1594 "U-251MG,
Human
Astrocytoma
","Laboratory of David Sabatini (MIT, USA)",RRID:CVCL_0021 "
MDA-MB-231
,
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Reviews
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NCI-H838 [H838] from ATCC
Supplier Page
View Company Product Page
$551.00
Product Specs
Company Info
Citations
Reviews
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