KG-1a from ATCC

Product Specs
ItemKG-1a
CompanyATCC
Price $431.00Supplier Page View Company Product Page
Catalog NumberCCL-246.1
TypeCell Biology
SpeciesHomo sapiens
TissueMarrow, Bone
Cell LineKG-1a
Validated Species ReactivityHuman (Hu)
Tissue (standardized)Blood
Cell Typepromyeloblast also macrophage cell
Age59 years
DiseaseAcute myelogenous leukemia
ApplicationsThis cell line is a suitable transfection host

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Differential Modulation of JAK/STAT3 Signaling and BCL-2 Family Proteins by Tetracycline Analogues in Leukemia ModelsPharmaceuticsMarch 28, 2026Zienab M. Hassan, Doste R. Mamand, Hoda W. El-Gawly, Nagla A. El-Sherbeeny, Hala M. F. Mohammad, Mohamed K. Elkherbetawy, Oscar P. B. Wiklander, Moustapha HassanSupplementary Materials. 2.2. Cell Culture The leukemia cell lines K562 (ATCC, CCL-243), KG-1a (ATCC, CCL-246.1), and Jurkat (ATCC, TIB-152) were selected to represent major hematological malignancy subtypes across

(2) Protein S -acylation dynamics provide metabolic plasticity to acute myeloid leukemia cellsbioRxivMarch 3, 2026Nithya Balasundaram, Ayşegül Erdem, Azeem Sharda, Veerle W. Daniels, Phillip L. Chea, Fleur Leguay, Youzhong Liu, Mark A. Keibler, Charles Vidoudez, Andrew A. Lane, et al.pull down",PRIDE,PXD074384 Experimental Models: Cell Lines,Experimental Models: Cell Lines,Experimental Models: Cell Lines KG1A,ATCC,CCL-246.1 NOMO1,Leibniz Institute DSMZ,ACC 542 OCI-AML3,Leibniz Institute DSMZ,ACC 582 U937,ATCC,CRL-1593.2 MONOMAC6,Leibniz

(3) An Isoform-Specific RUNX1C–BTG2 Axis Governs AML Quiescence and ChemoresistanceBlood Cancer DiscoverySeptember 3, 2025Cuijuan Han, Zhiping Zhang, Edie I. Crosse, Sogand Sajedi, Bin Lu, Xiyue Wang, Sadik Karma, Mitch Kostich, Sakthi Harini Rajendran, Dylan B. Udy, et al.#CRL-1593.2; RRID: CVCL_0007), HEK293T (ATCC, Cat. #CRL-1573; RRID: CVCL_0063), and KG-1a (ATCC, Cat. #CCL-246.1; RRID: CVCL_1824). AML PDXs Primary bone marrow and blood specimens were collected from patients with

(4) Id1 promotes clonal hematopoiesis in mice with Tet2 loss of functionSci AdvAugust 29, 2025Shweta Singh, Kristbjorn O. Gudmundsson, Tanmoy Sarkar, Brad L. Jakubison, Holly M. Morris, Sandra Burkett, Karim Baktiar, Gary T. Pauly, Dina M. Sigano, Joel P. Schneider, et al.collection, #ACC 104), K562 [American Type Culture Collection (ATCC), #CRL-3343], and KG1a (ATCC, #CCL-246.1) cells were grown as described by the supplier. Bone marrow transplantation For competitive bone marrow transplantation

(5) P-gp quantification for cell resistance studies in leukemia cells using the innovative LightSpot-FL-1 fluorescent conjugateSci RepMay 25, 2025Maxime Dubois, Antoine Goisnard, Céline Bourgne, Elodie Gay, Marie Depresle, Manon Roux, Allison Voisin, Marc Berger, Frédérique Penault-Llorca, Emmanuelle Mounetou, et al.lines culture The human T lymphoblast CCRF-CEM (CCL-119) and the promyeloblasts macrophage KG-1a (CCL-246.1) cell lines were purchased from ATCC and were tested for the absence of mycoplasma contamination (MycoplasmaCheck

(6) Preclinical development of tuspetinib for the treatment of acute myeloid leukemiaCancer Research CommunicationsJanuary 1, 2025Himangshu Sonowal, William G. Rice, Raphael Bejar, Joo-Yun Byun, Seung Hyun Jung, Ranjeet Sinha, Stephen B. Howellon request. Cell lines and growth inhibition assays MV-4-11 (CRL-9591), HS-5 (CRL-3611), and KG1a (CCL-246.1) cells were obtained from ATCC. MOLM-13 (ACC 554) and MOLM-14 (ACC 777) were obtained from DSMZ (Deutsche

(7) Metformin as an Enhancer for the Treatment of Chemoresistant CD34+ Acute Myeloid Leukemia CellsGenes (Basel)May 20, 2024Indre Krastinaite, Sergej Charkavliuk, Ruta Navakauskiene, Veronika Viktorija BorutinskaiteVA, USA) were stored, maintained, and cultivated according to “Handling information” (atcc.org, KG-1a–CCL-246.1). Cultivation was performed using IMDM media with 20% of Fetal Bovine Serum and 1% of Penicillin/Streptomycin

(8) Bioactive Potential of Olive Mill Waste Obtained from Cultivars Grown in the Island of MaltaFoodsApril 10, 2024Frederick Lia, Karen Attardcomprising human promyelocytic leukemia (HL-60) CCL-240, promyeloblast macrophage cell line (KG-1a) CCL-246.1, and ATRA-resistant NB4r2 cells, were cultured in RPMI medium. All cell lines were procured from ATCC.

(9) Dexamethasone potentiates chimeric antigen receptor T cell persistence and function by enhancing IL-7Rα expressionMolecular TherapyFebruary 7, 2024Ashlie M. Munoz, Ryan Urak, Ellie Taus, Hui-Ju Hsieh, Dennis Awuah, Vibhuti Vyas, Laura Lim, Katherine Jin, Shu-Hong Lin, Saul J. Priceman, et al.RPMI 1640 with 10% heat-inactivated fetal bovine serum (FBS) (Hyclone, SH30070.03HI). KG-1a (ATCC, CCL-246.1) and SUP-B15 (ATCC, CRL-1929) cells were cultured in IMDM (Life Technologies, 12440-053) with 10% heat-inactivated

(10) Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemiaiScienceJanuary 19, 2024Jiang X, Huang K, Sun X, Li Y, Hua L, Liu F, Huang R, Du J, Zeng H.CRL-9591 MOLM13,CTCC,Cat# CTCC-007-0236 THP-1,ATCC,Cat# TIB-202 Kasumi-1,ATCC,Cat# CRL-2724 KG-1α,ATCC,Cat# CCL-246.1 293T,ATCC,Cat# CRL-3216 ,, Experimental models: Organisms/strains,Experimental models: Organisms/strains,Experimental models

(11) Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemiaiScienceJune 16, 2023Ennis S, Conforte A, O'Reilly E, Takanlu JS, Cichocka T, Dhami SP, Nicholson P, Krebs P, Ó Broin P, Szegezdi E.cell line derived from the bone marrow of a male AML patient was purchased from ATCC (cat. Number: CCL-246.1). There was no in house authentication carried out. Method details Generation of scRNA-seq dataset Longitudinally-collected

(12) Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T CellsCancersMay 20, 2023Urak R, Gittins B, Soemardy C, Grepo N, Goldberg L, Maker M, Shevchenko G, Davis A, Li S, Scott T, et al.formaldehyde for 20 min at 4 °C. 2.3. Cell Lines Jurkats (ATCC TIB-152), LCL (ATCC CRL-1805), KG-1a (ATCC CCL-246.1), CEM (ATCC CRL-2265), and 8e5 (ATCC CRL-8993) cell lines were obtained from ATCC®. Cells were cultured

(13) Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cellsCell reports. MedicineMarch 21, 2023van der Werf I, Mondala PK, Steel SK, Balaian L, Ladel L, Mason CN, Diep RH, Pham J, Cloos J, Kaspers GJL, et al.lines ,, Kasumi-1,ATCC,Cat# CRL-2724; RRID:CVCL_0589 THP-1,ATCC,Cat# TIB-202; RRID:CVCL_0006 KG1a,ATCC,Cat# CCL-246.1; RRID:CVCL_1824 MOLM-13,DMSZ,Cat# ACC-554; RRID:CVCL_2119 "SI/SI (IL-3, CSF) (SL)",StemCell Technologies

(14) Reversal of malignant ADAR1 splice isoform switching with RebecsinibCell stem cellMarch 2, 2023Crews LA, Ma W, Ladel L, Pham J, Balaian L, Steel SK, Mondala PK, Diep RH, Wu CN, Mason CN, et al.lines,Experimental models: Cell lines human KG-1a cells (AML cells derived from a 59 y/o male),ATCC,CCL-246.1 human K562 cells (blast crisis chronic myeloid leukemia cells isolated from a 53 y/o female),ATCC,CRL-3344 human

(15) METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolismCell stem cellJanuary 5, 2023Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, et al.CVCL_0589 OCI-AML3,"Dr Ling Li (City of Hope, Duarte, CA)",N/A MONOMAC6,DSMZ,ACC-124; RRID: CVCL_1426 KG-1a,ATCC,CCL-246.1 MA9.3ITD,A gift from Dr. James Mulloy,N/A OP9,ATCC,CRL-2749; RRID: CVCL_4398 HEK293T,ATCC,CRL-3216;

(16) scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programsScientific ReportsDecember 1, 2022Kooper V. Hunt, Sean M. Burnard, Ellise A. Roper, Danielle R. Bond, Matthew D. Dun, Nicole M. Verrills, Anoop K. Enjeti, Heather J. Leeused more often and at scale. Methods Cell lines and patient samples KG1a cells (ATCC, catalog #CCL-246.1) were cultured in Iscove’s Modified Dulbecco’s Medium (IMDM) (Sigma-Aldrich, catalog # I3390) with 10%

(17) Targeted Nanoparticles for the Binding of Injured Vascular Endothelium after Percutaneous Coronary InterventionMoleculesNovember 23, 2022Pennapa Mungchan, Kittirat Glab-ampai, Nuttapol Chruewkamlow, Kongtana Trakarnsanga, Chatchawan Srisawat, Kytai T. Nguyen, Wanpen Chaicumpa, Primana Punnakitikashempenicillin-streptomycin (Invitrogen; Waltham, MA, USA). Acute myeloblastic leukemia cell line (KG-1a cells; ATCC® CCL-246.1TM) were cultured in IMDM medium (ATCC, Manassas, VA, USA) supplemented with 20% fetal bovine serum (FBS)

(18) Doxorubicin-Loaded Polymeric Micelles Conjugated with CKR- and EVQ-FLT3 Peptides for Cytotoxicity in Leukemic Stem CellsPharmaceuticsOctober 4, 2022Fah Chueahongthong, Singkome Tima, Sawitree Chiampanichayakul, Pornngarm Dejkriengkraikul, Siriporn Okonogi, Mathurada Sasarom, Soraya Rodwattanagul, Cory Berkland, Songyot AnuchapreedaUSA). 2.2. Cell Lines and Cell Culture Conditions KG-1a (human acute myeloblastic leukemic cell line; ATCC® CCL-246.1™) was purchased from ATCC (Manassas, VA, USA). EoL-1 (human eosinophilic leukemia cell line; RBRC-RCB0641)

(19) Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccineMolecular Therapy - Methods & Clinical DevelopmentJune 9, 2022Min Guan et al.eGFP-ffLuc, and GFP+gp120+ cells were sorted and expanded. Acute myeloid leukemia cell line KG-1a (CCL-246.1) cells were purchased from ATCC and maintained in 10% FCS IMDM medium and used as negative target cells.

(20) Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid LeukemiaCancer discoveryApril 1, 2022Galán-Díez M, Borot F, Ali AM, Zhao J, Gil-Iturbe E, Shan X, Luo N, Liu Y, Huang XP, Bisikirska B, et al.CCL-240, RRID: CVCL_0002), MV4-11 (ATCC, catalog no. CRL-9591, RRID: CVCL_0064), KG-1a (ATCC, catalog no. CCL-246.1, RRID: CVCL_1824), Kasumi-1 (ATCC, catalog no. CRL-2724, RRID: CVCL_0589), and HEK293T (ATCC, catalog

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KG-1a from ATCC

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