BE(2)-C from ATCC

Product Specs
ItemBE(2)-C
CompanyATCC
Price $0.00Supplier Page View Company Product Page
Catalog NumberCRL-2268
TypeCell Biology
SpeciesHomo sapiens
TissueBrain
Cell LineBE(2)-C
Validated Species ReactivityHuman (Hu)
Tissue (standardized)Brain
Cell Typeneuroblast
Age2 years
DiseaseNeuroblastoma

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Elevation of the mechanically-sensitive e protein emerin links nuclear mechanotransduction to tau-induced cytoskeletal remodeling in neuronsNucleusJuly 8, 2026Claira Sohn, Sammy Pardo, Dana Molleur, Satvik R. Paduri, Morgan Lambert, Zachary Uttke, Erich J. Sohn, Morgan G. Thomas, Susan T. Weintraub, Bess Frosttoxicity. Materials and methods BE(2)-C cell culture Human neuroblastoma cells (BE(2)-C; ATCC #CRL-2268) were cultured in a 1:1 mixture of Eagle’s Minimum Essential Medium (EMEM) and F12 medium supplemented

(2) Evaluation of the Individual Effects of Melatonin and Umbilical Cord-Derived Mesenchymal Stem Cell Exosomes on Cell Viability and Apoptosis in BE(2)-C Neuroblastoma Cells In VitroCurr Issues Mol BiolJune 16, 2026Ahmet Şengül, Dilek Kaan, Hatice Güler, Hüseyin YiğitCell Culture of the BE(2)-C Neuroblastoma Cell Line The Human Neuroblastoma BE(2)-C cell line (ATCC #CRL-2268, isolated from the brain of a male patient with neuroblastoma) was grown in a 1:1 mixture of DMEM/F12

(3) The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1Advanced ScienceMay 15, 2026Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, et al.(ACC355, DSMZ, Braunschweig, Germany), SY5Y (RRID:CVCL_0019) (CRL‐2266, ATCC), BE(2)C (RRID:CVCL_0529) (CRL‐2268, ATCC), and IMR‐32 (RRID:CVCL_0346) (CCL‐127, ATCC) were provided by Prof. I. Oehme, Heidelberg, Germany.

(4) Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimersElifeApril 30, 2026Xiaoyu Yu, Yuanjun He, Thedore M Kamenecka, Douglas J Kojetin414.1439. LCMS confirmed the purity was >95%. Cell lines for mammalian cell culture SK-N-BE(2)-C (#CRL-2268) cells were obtained from and authenticated by ATCC, determined to be mycoplasma free, and cultured

(5) Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimersElifeApril 30, 2026Xiaoyu Yu, Yuanjun He, Theodore M Kamenecka, Douglas J Kojetin414.1439. LCMS confirmed the purity was >95%. Cell lines for mammalian cell culture SK-N-BE(2)-C (#CRL-2268) cells were obtained from and authenticated by ATCC, determined to be mycoplasma free, and cultured

(6) LMO1 expression in neuroblastoma cells reprograms tumor-associated macrophages to promote metastasisiScienceMarch 20, 2026Ke-En Tan, Zuag Paj Her, Cheng Zhang, Kok Siong Yeo, Taylor Weiskittel, Cassie Howe, Shyang Hong Tan, Katherine M. Johnson, Gina L. Razidlo, Thomas E. Rubino, et al.was not observed in MYCN-only fish. Cell culture The human neuroblastoma cell line BE2C (ATCC Cat# CRL-2268, RRID: CVCL_0529) and the U937 (ATCC Cat# CRL-1593.2, RRID:CVCL_0007) human monocytes were obtained

(7) NAA20-mediated ACF1 lactylation drives neuroblastoma progression through enhancing GCLM-dependent glutathione synthesisCell Biol ToxicolFebruary 5, 2026Bingqiang Han, Min Xu, Qi Wang, Jianwei Lin, Jun Chu, Yunlan Xu, Dapeng Jianglines,Cell lines KELLY (Human Neuroblastoma),ECACC,"92,110,411" BE(2)C (Human Neuroblastoma),ATCC,CRL-2268 HEK293T,ATCC,CRL-3216 Software and algorithms,Software and algorithms,Software and algorithms R Project

(8) Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1The FEBS JournalJanuary 24, 2026Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, et al.Genomic integrity was periodically assessed through karyotyping. Cell lines The SK‐N‐BE(2)C (Cat#CRL‐2268; ATCC, Manassas, VA, USA; RRID: CVCL‐0529), IMR32 (Cat#CCL‐127; ATCC; RRID: CVCL‐0346), and SH‐SY5Y

(9) Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB SignalingAdvanced ScienceNovember 1, 2025Yanhua Guo, Xiaojing Wang, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Jiaying Qu, Shunchen Zhou, Liduan Zheng, Qiangsong Tong(CRL‐3216), SH‐SY5Y (CRL‐2266), SK‐N‐AS (CRL‐2137), SK‐N‐SH (HTB‐11), SK‐N‐BE(2) (CRL‐2271), BE(2)‐C (CRL‐2268), IMR‐32 (CCL‐127), and SK‐N‐DZ (CRL‐2149). All cell lines were authenticated through short tandem repeat

(10) Elevation of the mechanically-sensitive protein emerin links nuclear mechanotransduction to tau-induced cytoskeletal remodeling in neuronsbioRxivOctober 19, 2025Claira Sohn, Sammy Pardo, Dana Molleur, Satvik R Paduri, Morgan Lambert, Morgan G Thomas, Erich J Sohn, Susan T Weintraub, Bess Frosttau-induced toxicity. MATERIALS AND METHODS Cell culture Human neuroblastoma cells (BE(2)-C; ATCC #CRL-2268) were cultured in a 1:1 mixture of Eagle's minimum essential medium (EMEM) and F12 medium supplemented

(11) The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid MetabolismAdvanced ScienceSeptember 1, 2025Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, et al.cell lines were grown in Dulbecco's Modified Eagle Medium (DMEM, Sigma); the human SK‐N‐BE(2)C (ATCC, CRL‐2268) and LAN‐2 (ECACC, 0 604 1202) were grown in a 1:1 mixture of Minimum essential Medium Eagle (EMEM,

(12) Engineering affinity-matured variants of an anti-polysialic acid monoclonal antibody with superior cytotoxicity-mediating potencyCell Chemical BiologyAugust 21, 2025Weiyao Wang, Mehman Bunyatov, Deana Moffat, Natalia Lopez-Barbosa, Matthew P. DeLisaATCC: SH-SY5Y (cat # CRL-2266; sex = female), SKOV3 (cat # HTB-77; sex = female), SK-N-BE(2)-C (cat # CRL-2268; sex = male), IMR-32 (cat # CCL-127; sex = male), NCI-H69 (cat # HTB-119; sex = male), NCI-H82 (cat

(13) Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomicsNature communicationsAugust 20, 2025Steger M, Nishiguchi G, Wu Q, Schwalb B, Shashikadze B, McGowan K, Actis M, Aggarwal A, Shi Z, Price J, et al.and RH30 cell lines were provided by Dr. Gerald Grosveld at St Jude. The SK-N-BE(2)-C (BE(2)-C) (Cat# CRL-2268), Rh30, Kasumi-1 (Cat# CRL-2724), and Caki-1 (Cat# HTB-46) cell lines were obtained from ATCC. The SIMA

(14) In Vivo Antitumor Activity of Allicin in a Pediatric Neuroblastoma Patient-derived Xenograft (PDX) Mouse ModelIn VivoApril 28, 2025CHAD R. Schultz, MARTIN C.H. Gruhlke, ALAN J. Slusarenko, ANDRÉ S. Bachmann(CB_92110411) from Sigma-Aldrich (St. Louis, MO, USA). The SK-N-BE clone used was SK-N-Be(2)c (ATCC: CRL-2268). The MycoAlert™ PLUS Mycoplasma Detection Kit (Lonza, Basel, Switzerland) was used to monitor cells

(15) Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signaturesMolecular Systems BiologyApril 1, 2025Joshua L Justice, Todd M Greco, Josiah E Hutton, Tavis J Reed, Megan L Mair, Juan Botas, Ileana M Cristeawindows are provided in Table EV1. BE(2)-C cell culture and CRISPR knockout Human BE(2)-C cells (ATCC # CRL-2268) were cultured in F-12 medium mixed 1:1 with MEM and supplemented with 10% FBS. Mycoplasma screening

(16) The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastomaMolecular OncologyFebruary 21, 2025Mujahid Azfar, Weiman Gao, Chris Van den Haute, Lin Xiao, Mawar Karsa, Ruby Pandher, Ayu Karsa, Dayna Spurling, Emma Ronca, Angelika Bongers, et al.RRID:CVCL_0019) were purchased from ATCC, KELLY cells (ACC354, RRID:CVCL_2092) cells from DSMZ, BE(2)‐C cells (CRL‐2268, RRID:CVCL_0529) from ATCC, Tet‐21/N cells (RRID:CVCL_9812) were a gift from Manfred Schwab, German

(17) Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomicsCell Reports MethodsJuly 15, 2024Louis Delhaye, George D. Moschonas, Daria Fijalkowska, Annick Verhee, Delphine De Sutter, Tessa Van de Steene, Margaux De Meyer, Hanna Grzesik, Laura Van Moortel, Karolien De Bosscher, et al.HEK293T,ATCC,CRL-3216 Human: HeLa,ATCC,CCL-2 Human: SK-N-BE(2)-C,Laboratory of Frank Speleman (Ghent University),CRL-2268 Human: SHEP,Laboratory of Frank Speleman (Ghent University),CVCL_0524 ,, Oligonucleotides,Oligonucleotides,Oligonucleotides ,, SDHA_Fwd,This

(18) DFMO inhibition of neuroblastoma tumorigenesisCancer MedicineMay 1, 2024Divya Gandra, David H. Mulama, David M. Foureau, Kimberly Q. McKinney, Elizabeth Kim, Kaitlyn Smith, Jason Haw, Abhinav Nagulapally, Giselle L. Saulnier ShollerCell culture Drug treatments were conducted in vitro using five established human NB cell lines: BE2C (CRL‐2268, purchased from ATCC, Manassas, VA), SMS‐KCNR (from the Children's Hospital of Philadelphia, PA), CHLA‐90

(19) Activating Transcription Factor 5 (ATF5) Promotes Neuroblastoma Metastasis by Inducing Anoikis ResistanceCancer Research CommunicationsDecember 12, 2023Debarshi Banerjee, Shuobo Bobolla, Shunpei Okochi, James M. Angelastro, Angela V. Kadenhe-Chiweshe, Gonzalo Lopez, Andrea Califano, Eileen P. Connolly, Lloyd A. Greene, Darrell J. YamashiroMethods Cell Culture Human neuroblastoma cell lines were purchased from the ATCC: BE(2)-C (ATCC, catalog no. CRL-2268, RRID:CVCL_0529), SK-N-DZ (ATCC, catalog no. CRL-2149, RRID: CVCL_1701), and SH-SY5Y (ATCC, catalog

(20) Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis ResistanceCancer Res CommunDecember 12, 2023Debarshi Banerjee, Shuobo Boboila, Shunpei Okochi, James M. Angelastro, Angela V. Kadenhe-Chiweshe, Gonzalo Lopez, Andrea Califano, Eileen P. Connolly, Lloyd A. Greene, Darrell J. YamashiroMethods Cell Culture Human neuroblastoma cell lines were purchased from the ATCC: BE(2)-C (ATCC, catalog no. CRL-2268, RRID:CVCL_0529), SK-N-DZ (ATCC, catalog no. CRL-2149, RRID: CVCL_1701), and SH-SY5Y (ATCC, catalog

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